Reviewed,
UniProtKB/Swiss-Prot Q2KNB9 (HXK2_ORYSJ)
Last modified
January 19, 2010.
Version 24.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Hexokinase-2 EC=2.7.1.1 Alternative name(s): Hexokinase-3 | ||||||||
| Gene names |
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| Organism | Oryza sativa subsp. japonica (Rice) | ||||||||
| Taxonomic identifier | 39947 [NCBI] | ||||||||
| Taxonomic lineage | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza |
Protein attributes
| Sequence length | 494 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at transcript level. |
General annotation (Comments)
| Function | Fructose and glucose phosphorylating enzyme. Ref.1 |
| Catalytic activity | ATP + D-hexose = ADP + D-hexose 6-phosphate. |
| Tissue specificity | Expressed in roots, leaves, flowers, immature seeds, endosperm and seed coat. Ref.1 |
| Developmental stage | Expressed during flower development until 15 days after flowering. Ref.1 |
| Induction | By glucose or fructose treatment in leaves. Ref.1 |
| Sequence similarities | Belongs to the hexokinase family. |
| Sequence caution | The sequence AAT47078.1 differs from that shown. Reason: Erroneous gene model prediction. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Glycolysis |
| Ligand | ATP-binding Nucleotide-binding |
| Molecular function | Kinase Transferase |
| Gene Ontology (GO) | |
| Biological process | glycolysis Inferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | ATP binding Inferred from electronic annotation. Source: UniProtKB-KW hexokinase activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "Structure, expression, and functional analysis of the hexokinase gene family in rice (Oryza sativa L.)." Cho J.-I., Ryoo N., Ko S., Lee S.-K., Lee J., Jung K.-H., Lee Y.-H., Bhoo S.H., Winderickx J., An G., Hahn T.-R., Jeon J.-S. Planta 224:598-611(2006) [PubMed: 16552590] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE, INDUCTION, NOMENCLATURE. Strain: cv. Jinmi. |
| [2] | "The hexokinase gene family in rice." Wang Y.D., Cheng W., Wang X.S., Zhou X.J. Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Zhonghua 15. Tissue: Flower. |
| [3] | "A fine physical map of the rice chromosome 5." Cheng C.-H., Chung M.C., Liu S.-M., Chen S.-K., Kao F.Y., Lin S.-J., Hsiao S.-H., Tseng I.C., Hsing Y.-I.C., Wu H.-P., Chen C.-S., Shaw J.-F., Wu J., Matsumoto T., Sasaki T., Chen H.-C., Chow T.-Y. Mol. Genet. Genomics 274:337-345(2005) [PubMed: 16261349] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | DQ116384 mRNA. Translation: AAZ93619.1. AY884166 mRNA. Translation: AAX68419.1. AC121365 Genomic DNA. Translation: AAT47078.1. Sequence problems. |
3D structure databases | |
| SMR | Q2KNB9. Positions 40-487. |
| ModBase | Search... |
Organism-specific databases | |
| Gramene | Q2KNB9. |
Enzyme and pathway databases | |
| BRENDA | 2.7.1.1. 1975. |
Family and domain databases | |
| InterPro | IPR001312. Hexokinase. [Graphical view] |
| PANTHER | PTHR19443. Hexokinase. 1 hit. |
| Pfam | PF00349. Hexokinase_1. 1 hit. PF03727. Hexokinase_2. 1 hit. [Graphical view] |
| PRINTS | PR00475. HEXOKINASE. |
| PROSITE | PS00378. HEXOKINASES. False negative. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | HXK2_ORYSJ | ||||||||
| Accession | Primary (citable) accession number: Q2KNB9 Secondary accession number(s): Q6I5H8 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | PPAP (Plant Proteome Annotation Project) | ||||||||
Relevant documents
| Oryza sativa (rice) Index of Oryza sativa entries and their corresponding gene designations |
| SIMILARITY comments Index of protein domains and families |

Clusters with


