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Q2KJI1

- CKS2_BOVIN

UniProt

Q2KJI1 - CKS2_BOVIN

Protein

Cyclin-dependent kinases regulatory subunit 2

Gene

CKS2

Organism
Bos taurus (Bovine)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
  1. Functioni

    Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.By similarity

    GO - Molecular functioni

    1. cyclin-dependent protein serine/threonine kinase regulator activity Source: InterPro

    GO - Biological processi

    1. meiosis I Source: Ensembl

    Keywords - Biological processi

    Cell cycle, Cell division

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cyclin-dependent kinases regulatory subunit 2
    Short name:
    CKS-2
    Gene namesi
    Name:CKS2
    OrganismiBos taurus (Bovine)
    Taxonomic identifieri9913 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
    ProteomesiUP000009136: Chromosome 8

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11RemovedBy similarity
    Chaini2 – 7978Cyclin-dependent kinases regulatory subunit 2PRO_0000260447Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei2 – 21N-acetylalanineBy similarity
    Modified residuei4 – 41N6-acetyllysineBy similarity

    Keywords - PTMi

    Acetylation

    Proteomic databases

    PRIDEiQ2KJI1.

    Interactioni

    Subunit structurei

    Forms a homohexamer that can probably bind six kinase subunits.By similarity

    Protein-protein interaction databases

    STRINGi9913.ENSBTAP00000002522.

    Structurei

    3D structure databases

    ProteinModelPortaliQ2KJI1.
    SMRiQ2KJI1. Positions 2-79.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the CKS family.Curated

    Phylogenomic databases

    eggNOGiNOG272189.
    GeneTreeiENSGT00390000011006.
    HOVERGENiHBG003626.
    InParanoidiQ2KJI1.
    KOiK02219.
    OMAiFDDKFEY.
    OrthoDBiEOG735413.
    TreeFamiTF101142.

    Family and domain databases

    Gene3Di3.30.170.10. 1 hit.
    InterProiIPR000789. Cyclin-dep_kinase_reg-sub.
    [Graphical view]
    PfamiPF01111. CKS. 1 hit.
    [Graphical view]
    PRINTSiPR00296. CYCLINKINASE.
    SMARTiSM01084. CKS. 1 hit.
    [Graphical view]
    SUPFAMiSSF55637. SSF55637. 1 hit.
    PROSITEiPS00944. CKS_1. 1 hit.
    PS00945. CKS_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q2KJI1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAHKQIYYSD KYFDEHYEYR HVMLPRELSK QVPKTHLMSE EEWRRLGVQQ   50
    SLGWVHYMIH EPEPHILLFR RPLPKDQQK 79
    Length:79
    Mass (Da):9,860
    Last modified:March 7, 2006 - v1
    Checksum:i811B5927691EEC5C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC105331 mRNA. Translation: AAI05332.1.
    RefSeqiNP_001106790.1. NM_001113319.2.
    UniGeneiBt.13573.

    Genome annotation databases

    EnsembliENSBTAT00000002522; ENSBTAP00000002522; ENSBTAG00000001938.
    GeneIDi767985.
    KEGGibta:767985.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC105331 mRNA. Translation: AAI05332.1 .
    RefSeqi NP_001106790.1. NM_001113319.2.
    UniGenei Bt.13573.

    3D structure databases

    ProteinModelPortali Q2KJI1.
    SMRi Q2KJI1. Positions 2-79.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9913.ENSBTAP00000002522.

    Proteomic databases

    PRIDEi Q2KJI1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSBTAT00000002522 ; ENSBTAP00000002522 ; ENSBTAG00000001938 .
    GeneIDi 767985.
    KEGGi bta:767985.

    Organism-specific databases

    CTDi 1164.

    Phylogenomic databases

    eggNOGi NOG272189.
    GeneTreei ENSGT00390000011006.
    HOVERGENi HBG003626.
    InParanoidi Q2KJI1.
    KOi K02219.
    OMAi FDDKFEY.
    OrthoDBi EOG735413.
    TreeFami TF101142.

    Miscellaneous databases

    NextBioi 20918340.

    Family and domain databases

    Gene3Di 3.30.170.10. 1 hit.
    InterProi IPR000789. Cyclin-dep_kinase_reg-sub.
    [Graphical view ]
    Pfami PF01111. CKS. 1 hit.
    [Graphical view ]
    PRINTSi PR00296. CYCLINKINASE.
    SMARTi SM01084. CKS. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55637. SSF55637. 1 hit.
    PROSITEi PS00944. CKS_1. 1 hit.
    PS00945. CKS_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. NIH - Mammalian Gene Collection (MGC) project
      Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: Crossbred X Angus.
      Tissue: Ileum.

    Entry informationi

    Entry nameiCKS2_BOVIN
    AccessioniPrimary (citable) accession number: Q2KJI1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 28, 2006
    Last sequence update: March 7, 2006
    Last modified: October 1, 2014
    This is version 63 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3