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Q2KJI1

- CKS2_BOVIN

UniProt

Q2KJI1 - CKS2_BOVIN

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Protein

Cyclin-dependent kinases regulatory subunit 2

Gene
CKS2
Organism
Bos taurus (Bovine)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function By similarity.

GO - Molecular functioni

  1. cyclin-dependent protein serine/threonine kinase regulator activity Source: InterPro

GO - Biological processi

  1. meiosis I Source: Ensembl
Complete GO annotation...

Keywords - Biological processi

Cell cycle, Cell division

Names & Taxonomyi

Protein namesi
Recommended name:
Cyclin-dependent kinases regulatory subunit 2
Short name:
CKS-2
Gene namesi
Name:CKS2
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
ProteomesiUP000009136: Chromosome 8

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed By similarity
Chaini2 – 7978Cyclin-dependent kinases regulatory subunit 2PRO_0000260447Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylalanine By similarity
Modified residuei4 – 41N6-acetyllysine By similarity

Keywords - PTMi

Acetylation

Proteomic databases

PRIDEiQ2KJI1.

Interactioni

Subunit structurei

Forms a homohexamer that can probably bind six kinase subunits By similarity.

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000002522.

Structurei

3D structure databases

ProteinModelPortaliQ2KJI1.
SMRiQ2KJI1. Positions 2-79.

Family & Domainsi

Sequence similaritiesi

Belongs to the CKS family.

Phylogenomic databases

eggNOGiNOG272189.
GeneTreeiENSGT00390000011006.
HOVERGENiHBG003626.
InParanoidiQ2KJI1.
KOiK02219.
OMAiFDDKFEY.
OrthoDBiEOG735413.
TreeFamiTF101142.

Family and domain databases

Gene3Di3.30.170.10. 1 hit.
InterProiIPR000789. Cyclin-dep_kinase_reg-sub.
[Graphical view]
PfamiPF01111. CKS. 1 hit.
[Graphical view]
PRINTSiPR00296. CYCLINKINASE.
SMARTiSM01084. CKS. 1 hit.
[Graphical view]
SUPFAMiSSF55637. SSF55637. 1 hit.
PROSITEiPS00944. CKS_1. 1 hit.
PS00945. CKS_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q2KJI1-1 [UniParc]FASTAAdd to Basket

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MAHKQIYYSD KYFDEHYEYR HVMLPRELSK QVPKTHLMSE EEWRRLGVQQ   50
SLGWVHYMIH EPEPHILLFR RPLPKDQQK 79
Length:79
Mass (Da):9,860
Last modified:March 7, 2006 - v1
Checksum:i811B5927691EEC5C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC105331 mRNA. Translation: AAI05332.1.
RefSeqiNP_001106790.1. NM_001113319.2.
UniGeneiBt.13573.

Genome annotation databases

EnsembliENSBTAT00000002522; ENSBTAP00000002522; ENSBTAG00000001938.
GeneIDi767985.
KEGGibta:767985.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC105331 mRNA. Translation: AAI05332.1 .
RefSeqi NP_001106790.1. NM_001113319.2.
UniGenei Bt.13573.

3D structure databases

ProteinModelPortali Q2KJI1.
SMRi Q2KJI1. Positions 2-79.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 9913.ENSBTAP00000002522.

Proteomic databases

PRIDEi Q2KJI1.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSBTAT00000002522 ; ENSBTAP00000002522 ; ENSBTAG00000001938 .
GeneIDi 767985.
KEGGi bta:767985.

Organism-specific databases

CTDi 1164.

Phylogenomic databases

eggNOGi NOG272189.
GeneTreei ENSGT00390000011006.
HOVERGENi HBG003626.
InParanoidi Q2KJI1.
KOi K02219.
OMAi FDDKFEY.
OrthoDBi EOG735413.
TreeFami TF101142.

Miscellaneous databases

NextBioi 20918340.

Family and domain databases

Gene3Di 3.30.170.10. 1 hit.
InterProi IPR000789. Cyclin-dep_kinase_reg-sub.
[Graphical view ]
Pfami PF01111. CKS. 1 hit.
[Graphical view ]
PRINTSi PR00296. CYCLINKINASE.
SMARTi SM01084. CKS. 1 hit.
[Graphical view ]
SUPFAMi SSF55637. SSF55637. 1 hit.
PROSITEi PS00944. CKS_1. 1 hit.
PS00945. CKS_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. NIH - Mammalian Gene Collection (MGC) project
    Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Crossbred X Angus.
    Tissue: Ileum.

Entry informationi

Entry nameiCKS2_BOVIN
AccessioniPrimary (citable) accession number: Q2KJI1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: March 7, 2006
Last modified: May 14, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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