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Q2KJH6 (SERPH_BOVIN) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Serpin H1
Alternative name(s):
Collagen-binding protein
Short name=Colligin
Gene names
Name:SERPINH1
OrganismBos taurus (Bovine) [Reference proteome]
Taxonomic identifier9913 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos

Protein attributes

Sequence length418 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen By similarity.

Subcellular location

Endoplasmic reticulum lumen By similarity.

Sequence similarities

Belongs to the serpin family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1818 Potential
Chain19 – 418400Serpin H1
PRO_0000253604

Regions

Motif415 – 4184Prevents secretion from ER Potential
Compositional bias25 – 295Poly-Ala

Sites

Site377 – 3782Reactive bond homolog By similarity

Amino acid modifications

Modified residue941N6-succinyllysine By similarity
Modified residue2071N6-acetyllysine By similarity
Modified residue2961N6-succinyllysine By similarity
Modified residue3191N6-acetyllysine By similarity
Glycosylation1201N-linked (GlcNAc...) Potential
Glycosylation1251N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q2KJH6 [UniParc].

Last modified March 7, 2006. Version 1.
Checksum: DE81C53C711EF152

FASTA41846,507
        10         20         30         40         50         60 
MRALLLISTI CLLARALAAE VKKPAAAAAP GTAEKLSPKA ATLAERSAGL AFSLYQAMAK 

        70         80         90        100        110        120 
DQAVENILLS PVVVASSLGL VSLGGKAATA SQAKAVLSAE QLRDDEVHAG LGELLRSLSN 

       130        140        150        160        170        180 
STARNVTWKL GSRLYGPSSV SFAEDFVRSS KQHYNCEHSK INFRDKRSAL QSINEWAAQT 

       190        200        210        220        230        240 
TDGKLPEVTK DVERTDGALL VNAMFFKPHW DERFHHKMVD NRGFMVTRSY TVGVTMMHRT 

       250        260        270        280        290        300 
GLYNYYDDEK EKLQMVEMPL AHKLSSLIII MPHHVEPLER LEKLLTKEQL KVWMGKMQKK 

       310        320        330        340        350        360 
AVAISLPKGV VEVTHDLQKH LAGLGLTEAI DKNKADLSRM SGKKDLYLAS VFHATAFEWD 

       370        380        390        400        410 
TDGNPFDQDI YGREELRSPK LFYADHPFIF LVRDTQSGSL LFIGRLVRPK GDKMRDEL 

« Hide

References

[1]NIH - Mammalian Gene Collection (MGC) project
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: Crossbred X Angus.
Tissue: Ileum.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC105338 mRNA. Translation: AAI05339.1.
RefSeqNP_001039528.1. NM_001046063.1.
XP_005216304.1. XM_005216247.1.
XP_005216305.1. XM_005216248.1.
UniGeneBt.21385.

3D structure databases

ProteinModelPortalQ2KJH6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING9913.ENSBTAP00000039506.

Protein family/group databases

MEROPSI04.036.

Proteomic databases

PaxDbQ2KJH6.
PRIDEQ2KJH6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSBTAT00000039717; ENSBTAP00000039506; ENSBTAG00000001027.
GeneID510850.
KEGGbta:510850.

Organism-specific databases

CTD871.

Phylogenomic databases

eggNOGCOG4826.
GeneTreeENSGT00750000117718.
HOGENOMHOG000238519.
HOVERGENHBG104930.
InParanoidQ2KJH6.
KOK09501.
OMAGVPMMHR.
OrthoDBEOG7GBFX4.
TreeFamTF343094.

Family and domain databases

InterProIPR023795. Serpin_CS.
IPR023796. Serpin_dom.
IPR000215. Serpin_fam.
[Graphical view]
PANTHERPTHR11461. PTHR11461. 1 hit.
PfamPF00079. Serpin. 1 hit.
[Graphical view]
SMARTSM00093. SERPIN. 1 hit.
[Graphical view]
SUPFAMSSF56574. SSF56574. 1 hit.
PROSITEPS00014. ER_TARGET. 1 hit.
PS00284. SERPIN. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio20869650.

Entry information

Entry nameSERPH_BOVIN
AccessionPrimary (citable) accession number: Q2KJH6
Entry history
Integrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: March 7, 2006
Last modified: May 14, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families