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Protein

Macrophage-expressed gene 1 protein

Gene

MPEG1

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Macrophage-expressed gene 1 protein
Short name:
Macrophage gene 1 protein
Short name:
Mpg-1
Gene namesi
Name:MPEG1
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Unplaced

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini25 – 655631ExtracellularSequence analysisAdd
BLAST
Transmembranei656 – 67621HelicalSequence analysisAdd
BLAST
Topological domaini677 – 71741CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2424Sequence analysisAdd
BLAST
Chaini25 – 717693Macrophage-expressed gene 1 proteinPRO_0000324142Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi185 – 1851N-linked (GlcNAc...)Sequence analysis
Glycosylationi255 – 2551N-linked (GlcNAc...)Sequence analysis
Glycosylationi269 – 2691N-linked (GlcNAc...)Sequence analysis
Glycosylationi375 – 3751N-linked (GlcNAc...)Sequence analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

PRIDEiQ2KJC3.

Structurei

3D structure databases

ProteinModelPortaliQ2KJC3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini30 – 345316MACPFPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 MACPF domain.PROSITE-ProRule annotation

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

HOVERGENiHBG057416.
InParanoidiQ2KJC3.

Family and domain databases

InterProiIPR020864. MACPF.
[Graphical view]
PfamiPF01823. MACPF. 1 hit.
[Graphical view]
SMARTiSM00457. MACPF. 1 hit.
[Graphical view]
PROSITEiPS51412. MACPF_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q2KJC3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNSFRGAFLI WAVATWAETD TSWGATDEPG FQNCKNALKL PVLPVLPGGG
60 70 80 90 100
WDNLRNVDTG RVMELAYSHC RTTEDGQYIV PDEIFTIPQK QSNLEMNSKI
110 120 130 140 150
LESWVNYQSS TSNSINMELS LFSKVNGKFS LEFQRIKTLQ VKDQAVTTQV
160 170 180 190 200
QVRNLVYTVK INPDAELSLG FKKALMDISE QLENNQTRMA TYLAELLVLN
210 220 230 240 250
YGTHVITSVD AGAALIQEDH IRSSFLQDSQ SSRSAVTASA GITFLNIVNF
260 270 280 290 300
KFEENYTSQN TFTKSYLSNR TNSRVQSFGG LPFYPGITLQ AWQQGVSNHL
310 320 330 340 350
VAMDRAGLPL YFFINPERLP DLPGPLVRKL SKTVEAAVRR YYAVNTYPGC
360 370 380 390 400
TDLSSPNFNF QANTDDGSCE GKMTNFSFGG VYQECTQFSG NEVVQLCQNL
410 420 430 440 450
EQKNPLTGSV SCPSGYSPVQ LLTQTHEEGY NHLECSRKCT LYIFCKTVCE
460 470 480 490 500
DVFRVARAEF RAFWCAASGQ VSENSGLLFG GLFSGKSINP LTNAQSCPAG
510 520 530 540 550
YFQLKLFENL KVCASLDYEL GYRFSIPFGG FFSCAAGNPL VDSATSKDLG
560 570 580 590 600
APSLRKCPGG FSQHLALISD GCQVSYCVKA GLFTGGSLPP VRLPPYTRPP
610 620 630 640 650
LMSQVATNTV LVTNHETASS WIKDPQTHQW RLGEPLELRR AMRVVHGDGE
660 670 680 690 700
GLSGGAAAGL TLGVTIALAG VVALAIYGAR KSRKKGYQAL QDEKQSLAAG
710
AAVNGDALDQ EQAQNPA
Length:717
Mass (Da):78,413
Last modified:March 18, 2008 - v2
Checksum:i9AF152AC3C6F2B87
GO

Sequence cautioni

The sequence AAI05416.1 differs from that shown. Reason: Frameshift at position 697. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC105415 mRNA. Translation: AAI05416.1. Frameshift.
RefSeqiNP_001039929.1. NM_001046464.1.
UniGeneiBt.42012.

Genome annotation databases

GeneIDi539997.
KEGGibta:539997.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC105415 mRNA. Translation: AAI05416.1. Frameshift.
RefSeqiNP_001039929.1. NM_001046464.1.
UniGeneiBt.42012.

3D structure databases

ProteinModelPortaliQ2KJC3.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ2KJC3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi539997.
KEGGibta:539997.

Organism-specific databases

CTDi219972.

Phylogenomic databases

HOVERGENiHBG057416.
InParanoidiQ2KJC3.

Family and domain databases

InterProiIPR020864. MACPF.
[Graphical view]
PfamiPF01823. MACPF. 1 hit.
[Graphical view]
SMARTiSM00457. MACPF. 1 hit.
[Graphical view]
PROSITEiPS51412. MACPF_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. NIH - Mammalian Gene Collection (MGC) project
    Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Hereford.
    Tissue: Hypothalamus.

Entry informationi

Entry nameiMPEG1_BOVIN
AccessioniPrimary (citable) accession number: Q2KJC3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: March 18, 2008
Last modified: June 8, 2016
This is version 40 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.