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Q2KJ39

- RCN3_BOVIN

UniProt

Q2KJ39 - RCN3_BOVIN

Protein

Reticulocalbin-3

Gene

RCN3

Organism
Bos taurus (Bovine)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 57 (01 Oct 2014)
      Sequence version 1 (07 Mar 2006)
      Previous versions | rss
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    Functioni

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Calcium bindingi90 – 101121; possibly ancestralPROSITE-ProRule annotationAdd
    BLAST
    Calcium bindingi126 – 137122PROSITE-ProRule annotationAdd
    BLAST
    Calcium bindingi176 – 187123; possibly ancestralPROSITE-ProRule annotationAdd
    BLAST
    Calcium bindingi213 – 224124PROSITE-ProRule annotationAdd
    BLAST
    Calcium bindingi254 – 265125PROSITE-ProRule annotationAdd
    BLAST
    Calcium bindingi290 – 301126PROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. calcium ion binding Source: InterPro

    Keywords - Ligandi

    Calcium, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Reticulocalbin-3
    Gene namesi
    Name:RCN3
    OrganismiBos taurus (Bovine)
    Taxonomic identifieri9913 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
    ProteomesiUP000009136: Chromosome 18

    Subcellular locationi

    Endoplasmic reticulum lumen PROSITE-ProRule annotation

    GO - Cellular componenti

    1. endoplasmic reticulum lumen Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Endoplasmic reticulum

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2020Sequence AnalysisAdd
    BLAST
    Chaini21 – 328308Reticulocalbin-3PRO_0000240340Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi140 – 1401N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi262 – 2621N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Proteomic databases

    PRIDEiQ2KJ39.

    Interactioni

    Protein-protein interaction databases

    STRINGi9913.ENSBTAP00000031823.

    Structurei

    3D structure databases

    ProteinModelPortaliQ2KJ39.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini75 – 11238EF-hand 1PROSITE-ProRule annotationAdd
    BLAST
    Domaini113 – 14836EF-hand 2PROSITE-ProRule annotationAdd
    BLAST
    Domaini163 – 19836EF-hand 3PROSITE-ProRule annotationAdd
    BLAST
    Domaini200 – 23536EF-hand 4PROSITE-ProRule annotationAdd
    BLAST
    Domaini241 – 27636EF-hand 5PROSITE-ProRule annotationAdd
    BLAST
    Domaini277 – 31236EF-hand 6PROSITE-ProRule annotationAdd
    BLAST

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi325 – 3284Prevents secretion from ERPROSITE-ProRule annotation

    Sequence similaritiesi

    Belongs to the CREC family.Curated
    Contains 6 EF-hand domains.PROSITE-ProRule annotation

    Keywords - Domaini

    Repeat, Signal

    Phylogenomic databases

    eggNOGiNOG286499.
    GeneTreeiENSGT00550000074546.
    HOGENOMiHOG000230934.
    HOVERGENiHBG002834.
    InParanoidiQ2KJ39.
    OMAiSDAPHDD.
    OrthoDBiEOG73Z2TD.
    TreeFamiTF314849.

    Family and domain databases

    Gene3Di1.10.238.10. 2 hits.
    InterProiIPR011992. EF-hand-dom_pair.
    IPR018247. EF_Hand_1_Ca_BS.
    IPR002048. EF_hand_dom.
    [Graphical view]
    PfamiPF13202. EF-hand_5. 1 hit.
    PF13499. EF-hand_7. 1 hit.
    [Graphical view]
    SMARTiSM00054. EFh. 3 hits.
    [Graphical view]
    PROSITEiPS00018. EF_HAND_1. 4 hits.
    PS50222. EF_HAND_2. 5 hits.
    PS00014. ER_TARGET. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q2KJ39-1 [UniParc]FASTAAdd to Basket

    « Hide

    MMWPPSLLLL LLLLRRGAQG KPSPDAGPHG QGRVHHAAPL SEAPHDDAHG    50
    NFQYDHEAFL GREVAKEFDQ LTPEESQARL GRIVDRMDRA GDGDGWVSLA 100
    ELRSWIAHTQ QRHIRDSVSA AWNTYDTDRD GRVGWEELRN ATYGHYEPGE 150
    EFHDVEDAET YKKMLARDER RFRVADQDGD SMATREELTA FLHPEEFPHM 200
    RDIVIAETLE DLDRNKDGYV QVEEYIADLY TAEPGEEEPA WVQTEREQFR 250
    DFRDLNKDGK LNGSEVGHWV LPPAQDQPLV EANHLLHESD TDKDGRLSKA 300
    EILGNWNMFV GSQATNYGED LTRHHDEL 328
    Length:328
    Mass (Da):37,568
    Last modified:March 7, 2006 - v1
    Checksum:i4D5FB9AF2D81FAEA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC105535 mRNA. Translation: AAI05536.1.
    RefSeqiNP_001039725.1. NM_001046260.1.
    UniGeneiBt.48738.

    Genome annotation databases

    EnsembliENSBTAT00000031877; ENSBTAP00000031823; ENSBTAG00000021799.
    GeneIDi522073.
    KEGGibta:522073.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC105535 mRNA. Translation: AAI05536.1 .
    RefSeqi NP_001039725.1. NM_001046260.1.
    UniGenei Bt.48738.

    3D structure databases

    ProteinModelPortali Q2KJ39.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9913.ENSBTAP00000031823.

    Proteomic databases

    PRIDEi Q2KJ39.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSBTAT00000031877 ; ENSBTAP00000031823 ; ENSBTAG00000021799 .
    GeneIDi 522073.
    KEGGi bta:522073.

    Organism-specific databases

    CTDi 57333.

    Phylogenomic databases

    eggNOGi NOG286499.
    GeneTreei ENSGT00550000074546.
    HOGENOMi HOG000230934.
    HOVERGENi HBG002834.
    InParanoidi Q2KJ39.
    OMAi SDAPHDD.
    OrthoDBi EOG73Z2TD.
    TreeFami TF314849.

    Miscellaneous databases

    NextBioi 20873441.

    Family and domain databases

    Gene3Di 1.10.238.10. 2 hits.
    InterProi IPR011992. EF-hand-dom_pair.
    IPR018247. EF_Hand_1_Ca_BS.
    IPR002048. EF_hand_dom.
    [Graphical view ]
    Pfami PF13202. EF-hand_5. 1 hit.
    PF13499. EF-hand_7. 1 hit.
    [Graphical view ]
    SMARTi SM00054. EFh. 3 hits.
    [Graphical view ]
    PROSITEi PS00018. EF_HAND_1. 4 hits.
    PS50222. EF_HAND_2. 5 hits.
    PS00014. ER_TARGET. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. NIH - Mammalian Gene Collection (MGC) project
      Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: Hereford.
      Tissue: Uterus.

    Entry informationi

    Entry nameiRCN3_BOVIN
    AccessioniPrimary (citable) accession number: Q2KJ39
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 27, 2006
    Last sequence update: March 7, 2006
    Last modified: October 1, 2014
    This is version 57 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3