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Q2KJ39

- RCN3_BOVIN

UniProt

Q2KJ39 - RCN3_BOVIN

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Protein

Reticulocalbin-3

Gene

RCN3

Organism
Bos taurus (Bovine)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Calcium bindingi90 – 101121; possibly ancestralPROSITE-ProRule annotationAdd
BLAST
Calcium bindingi126 – 137122PROSITE-ProRule annotationAdd
BLAST
Calcium bindingi176 – 187123; possibly ancestralPROSITE-ProRule annotationAdd
BLAST
Calcium bindingi213 – 224124PROSITE-ProRule annotationAdd
BLAST
Calcium bindingi254 – 265125PROSITE-ProRule annotationAdd
BLAST
Calcium bindingi290 – 301126PROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

  1. calcium ion binding Source: InterPro
Complete GO annotation...

Keywords - Ligandi

Calcium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Reticulocalbin-3
Gene namesi
Name:RCN3
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
ProteomesiUP000009136: Chromosome 18

Subcellular locationi

Endoplasmic reticulum lumen PROSITE-ProRule annotation

GO - Cellular componenti

  1. endoplasmic reticulum Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2020Sequence AnalysisAdd
BLAST
Chaini21 – 328308Reticulocalbin-3PRO_0000240340Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi140 – 1401N-linked (GlcNAc...)Sequence Analysis
Glycosylationi262 – 2621N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

PRIDEiQ2KJ39.

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000031823.

Structurei

3D structure databases

ProteinModelPortaliQ2KJ39.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini75 – 11238EF-hand 1PROSITE-ProRule annotationAdd
BLAST
Domaini113 – 14836EF-hand 2PROSITE-ProRule annotationAdd
BLAST
Domaini163 – 19836EF-hand 3PROSITE-ProRule annotationAdd
BLAST
Domaini200 – 23536EF-hand 4PROSITE-ProRule annotationAdd
BLAST
Domaini241 – 27636EF-hand 5PROSITE-ProRule annotationAdd
BLAST
Domaini277 – 31236EF-hand 6PROSITE-ProRule annotationAdd
BLAST

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi325 – 3284Prevents secretion from ERPROSITE-ProRule annotation

Sequence similaritiesi

Belongs to the CREC family.Curated
Contains 6 EF-hand domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

eggNOGiNOG286499.
GeneTreeiENSGT00550000074546.
HOGENOMiHOG000230934.
HOVERGENiHBG002834.
InParanoidiQ2KJ39.
OMAiSDAPHDD.
OrthoDBiEOG73Z2TD.
TreeFamiTF314849.

Family and domain databases

Gene3Di1.10.238.10. 2 hits.
InterProiIPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
[Graphical view]
PfamiPF13202. EF-hand_5. 1 hit.
PF13499. EF-hand_7. 1 hit.
[Graphical view]
SMARTiSM00054. EFh. 3 hits.
[Graphical view]
PROSITEiPS00018. EF_HAND_1. 4 hits.
PS50222. EF_HAND_2. 5 hits.
PS00014. ER_TARGET. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q2KJ39-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MMWPPSLLLL LLLLRRGAQG KPSPDAGPHG QGRVHHAAPL SEAPHDDAHG
60 70 80 90 100
NFQYDHEAFL GREVAKEFDQ LTPEESQARL GRIVDRMDRA GDGDGWVSLA
110 120 130 140 150
ELRSWIAHTQ QRHIRDSVSA AWNTYDTDRD GRVGWEELRN ATYGHYEPGE
160 170 180 190 200
EFHDVEDAET YKKMLARDER RFRVADQDGD SMATREELTA FLHPEEFPHM
210 220 230 240 250
RDIVIAETLE DLDRNKDGYV QVEEYIADLY TAEPGEEEPA WVQTEREQFR
260 270 280 290 300
DFRDLNKDGK LNGSEVGHWV LPPAQDQPLV EANHLLHESD TDKDGRLSKA
310 320
EILGNWNMFV GSQATNYGED LTRHHDEL
Length:328
Mass (Da):37,568
Last modified:March 7, 2006 - v1
Checksum:i4D5FB9AF2D81FAEA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC105535 mRNA. Translation: AAI05536.1.
RefSeqiNP_001039725.1. NM_001046260.1.
UniGeneiBt.48738.

Genome annotation databases

EnsembliENSBTAT00000031877; ENSBTAP00000031823; ENSBTAG00000021799.
GeneIDi522073.
KEGGibta:522073.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC105535 mRNA. Translation: AAI05536.1 .
RefSeqi NP_001039725.1. NM_001046260.1.
UniGenei Bt.48738.

3D structure databases

ProteinModelPortali Q2KJ39.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 9913.ENSBTAP00000031823.

Proteomic databases

PRIDEi Q2KJ39.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSBTAT00000031877 ; ENSBTAP00000031823 ; ENSBTAG00000021799 .
GeneIDi 522073.
KEGGi bta:522073.

Organism-specific databases

CTDi 57333.

Phylogenomic databases

eggNOGi NOG286499.
GeneTreei ENSGT00550000074546.
HOGENOMi HOG000230934.
HOVERGENi HBG002834.
InParanoidi Q2KJ39.
OMAi SDAPHDD.
OrthoDBi EOG73Z2TD.
TreeFami TF314849.

Miscellaneous databases

NextBioi 20873441.

Family and domain databases

Gene3Di 1.10.238.10. 2 hits.
InterProi IPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
[Graphical view ]
Pfami PF13202. EF-hand_5. 1 hit.
PF13499. EF-hand_7. 1 hit.
[Graphical view ]
SMARTi SM00054. EFh. 3 hits.
[Graphical view ]
PROSITEi PS00018. EF_HAND_1. 4 hits.
PS50222. EF_HAND_2. 5 hits.
PS00014. ER_TARGET. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. NIH - Mammalian Gene Collection (MGC) project
    Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Hereford.
    Tissue: Uterus.

Entry informationi

Entry nameiRCN3_BOVIN
AccessioniPrimary (citable) accession number: Q2KJ39
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: March 7, 2006
Last modified: October 29, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3