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Q2KJ39

- RCN3_BOVIN

UniProt

Q2KJ39 - RCN3_BOVIN

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Protein

Reticulocalbin-3

Gene
RCN3
Organism
Bos taurus (Bovine)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Calcium bindingi90 – 101121; possibly ancestral Reviewed predictionAdd
BLAST
Calcium bindingi126 – 137122 Reviewed predictionAdd
BLAST
Calcium bindingi176 – 187123; possibly ancestral Reviewed predictionAdd
BLAST
Calcium bindingi213 – 224124 Reviewed predictionAdd
BLAST
Calcium bindingi254 – 265125 Reviewed predictionAdd
BLAST
Calcium bindingi290 – 301126 Reviewed predictionAdd
BLAST

GO - Molecular functioni

  1. calcium ion binding Source: InterPro
Complete GO annotation...

Keywords - Ligandi

Calcium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Reticulocalbin-3
Gene namesi
Name:RCN3
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
ProteomesiUP000009136: Chromosome 18

Subcellular locationi

Endoplasmic reticulum lumen Reviewed prediction

GO - Cellular componenti

  1. endoplasmic reticulum lumen Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2020 Reviewed predictionAdd
BLAST
Chaini21 – 328308Reticulocalbin-3PRO_0000240340Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi140 – 1401N-linked (GlcNAc...) Reviewed prediction
Glycosylationi262 – 2621N-linked (GlcNAc...) Reviewed prediction

Keywords - PTMi

Glycoprotein

Proteomic databases

PRIDEiQ2KJ39.

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000031823.

Structurei

3D structure databases

ProteinModelPortaliQ2KJ39.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini75 – 11238EF-hand 1Add
BLAST
Domaini113 – 14836EF-hand 2Add
BLAST
Domaini163 – 19836EF-hand 3Add
BLAST
Domaini200 – 23536EF-hand 4Add
BLAST
Domaini241 – 27636EF-hand 5Add
BLAST
Domaini277 – 31236EF-hand 6Add
BLAST

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi325 – 3284Prevents secretion from ER Reviewed prediction

Sequence similaritiesi

Belongs to the CREC family.
Contains 6 EF-hand domains.

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

eggNOGiNOG286499.
GeneTreeiENSGT00550000074546.
HOGENOMiHOG000230934.
HOVERGENiHBG002834.
InParanoidiQ2KJ39.
OMAiSDAPHDD.
OrthoDBiEOG73Z2TD.
TreeFamiTF314849.

Family and domain databases

Gene3Di1.10.238.10. 2 hits.
InterProiIPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
[Graphical view]
PfamiPF13202. EF-hand_5. 1 hit.
PF13499. EF-hand_7. 1 hit.
[Graphical view]
SMARTiSM00054. EFh. 3 hits.
[Graphical view]
PROSITEiPS00018. EF_HAND_1. 4 hits.
PS50222. EF_HAND_2. 5 hits.
PS00014. ER_TARGET. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q2KJ39-1 [UniParc]FASTAAdd to Basket

« Hide

MMWPPSLLLL LLLLRRGAQG KPSPDAGPHG QGRVHHAAPL SEAPHDDAHG    50
NFQYDHEAFL GREVAKEFDQ LTPEESQARL GRIVDRMDRA GDGDGWVSLA 100
ELRSWIAHTQ QRHIRDSVSA AWNTYDTDRD GRVGWEELRN ATYGHYEPGE 150
EFHDVEDAET YKKMLARDER RFRVADQDGD SMATREELTA FLHPEEFPHM 200
RDIVIAETLE DLDRNKDGYV QVEEYIADLY TAEPGEEEPA WVQTEREQFR 250
DFRDLNKDGK LNGSEVGHWV LPPAQDQPLV EANHLLHESD TDKDGRLSKA 300
EILGNWNMFV GSQATNYGED LTRHHDEL 328
Length:328
Mass (Da):37,568
Last modified:March 7, 2006 - v1
Checksum:i4D5FB9AF2D81FAEA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC105535 mRNA. Translation: AAI05536.1.
RefSeqiNP_001039725.1. NM_001046260.1.
UniGeneiBt.48738.

Genome annotation databases

EnsembliENSBTAT00000031877; ENSBTAP00000031823; ENSBTAG00000021799.
GeneIDi522073.
KEGGibta:522073.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC105535 mRNA. Translation: AAI05536.1 .
RefSeqi NP_001039725.1. NM_001046260.1.
UniGenei Bt.48738.

3D structure databases

ProteinModelPortali Q2KJ39.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 9913.ENSBTAP00000031823.

Proteomic databases

PRIDEi Q2KJ39.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSBTAT00000031877 ; ENSBTAP00000031823 ; ENSBTAG00000021799 .
GeneIDi 522073.
KEGGi bta:522073.

Organism-specific databases

CTDi 57333.

Phylogenomic databases

eggNOGi NOG286499.
GeneTreei ENSGT00550000074546.
HOGENOMi HOG000230934.
HOVERGENi HBG002834.
InParanoidi Q2KJ39.
OMAi SDAPHDD.
OrthoDBi EOG73Z2TD.
TreeFami TF314849.

Miscellaneous databases

NextBioi 20873441.

Family and domain databases

Gene3Di 1.10.238.10. 2 hits.
InterProi IPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
[Graphical view ]
Pfami PF13202. EF-hand_5. 1 hit.
PF13499. EF-hand_7. 1 hit.
[Graphical view ]
SMARTi SM00054. EFh. 3 hits.
[Graphical view ]
PROSITEi PS00018. EF_HAND_1. 4 hits.
PS50222. EF_HAND_2. 5 hits.
PS00014. ER_TARGET. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. NIH - Mammalian Gene Collection (MGC) project
    Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Hereford.
    Tissue: Uterus.

Entry informationi

Entry nameiRCN3_BOVIN
AccessioniPrimary (citable) accession number: Q2KJ39
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: March 7, 2006
Last modified: February 19, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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