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Protein

Serine/threonine-protein phosphatase

Gene

PPP6C

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotation

Keywords - Ligandi

ManganeseSAAS annotation

Enzyme and pathway databases

ReactomeiR-BTA-204005. COPII (Coat Protein 2) Mediated Vesicle Transport.

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphataseUniRule annotation (EC:3.1.3.16UniRule annotation)
Gene namesi
Name:PPP6CImported
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 11

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000010568.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini110 – 1156SER_THR_PHOSPHATASEInterPro annotation

Sequence similaritiesi

Belongs to the PPP phosphatase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0373. Eukaryota.
ENOG410XNR9. LUCA.
GeneTreeiENSGT00550000074961.
HOGENOMiHOG000172696.
HOVERGENiHBG000216.
KOiK15498.
OMAiYKYHFPE.
OrthoDBiEOG74N5H2.
TreeFamiTF105563.

Family and domain databases

Gene3Di3.60.21.10. 1 hit.
InterProiIPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSiPR00114. STPHPHTASE.
SMARTiSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMiSSF56300. SSF56300. 1 hit.
PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2KIC7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPLDLDKYV EIARLCKYLP ENDLKRLCDY VCDLLLEESN VQPVSTPVTV
60 70 80 90 100
CGDIHGQFYD LCELFRTGGQ VPDTNYIFMG DFVDRGYYSL ETFTYLLALK
110 120 130 140 150
AKWPDRITLL RGNHESRQIT QVYGFYDECQ TKYGNANAWR YCTKVFDMLT
160 170 180 190 200
VAALIDEQIL CVHGGLSPDI KTLDQIRTIE RNQEIPHKGA FCDLVWSDPE
210 220 230 240 250
DVDTWAISPR GAGWLFGAKV TNEFVHINNL KLICRAHQLV HEGYKFMFDE
260 270 280 290 300
KLVTVWSAPN YCYRCGNIAS IMVFKDVNTR EPKLFRAVPD SERVIPPRTT

TPYFL
Length:305
Mass (Da):35,144
Last modified:January 15, 2008 - v2
Checksum:i55E95DB6CEA7CFF4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02032114 Genomic DNA. No translation available.
DAAA02032115 Genomic DNA. No translation available.
BC112686 mRNA. Translation: AAI12687.2.
RefSeqiNP_001124222.1. NM_001130750.1.
UniGeneiBt.17425.

Genome annotation databases

EnsembliENSBTAT00000010568; ENSBTAP00000010568; ENSBTAG00000008033.
GeneIDi511058.
KEGGibta:511058.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02032114 Genomic DNA. No translation available.
DAAA02032115 Genomic DNA. No translation available.
BC112686 mRNA. Translation: AAI12687.2.
RefSeqiNP_001124222.1. NM_001130750.1.
UniGeneiBt.17425.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000010568.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000010568; ENSBTAP00000010568; ENSBTAG00000008033.
GeneIDi511058.
KEGGibta:511058.

Organism-specific databases

CTDi5537.

Phylogenomic databases

eggNOGiKOG0373. Eukaryota.
ENOG410XNR9. LUCA.
GeneTreeiENSGT00550000074961.
HOGENOMiHOG000172696.
HOVERGENiHBG000216.
KOiK15498.
OMAiYKYHFPE.
OrthoDBiEOG74N5H2.
TreeFamiTF105563.

Enzyme and pathway databases

ReactomeiR-BTA-204005. COPII (Coat Protein 2) Mediated Vesicle Transport.

Family and domain databases

Gene3Di3.60.21.10. 1 hit.
InterProiIPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSiPR00114. STPHPHTASE.
SMARTiSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMiSSF56300. SSF56300. 1 hit.
PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: HerefordImported.
    Tissue: HypothalamusImported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HerefordImported.
  3. Ensembl
    Submitted (MAR-2016) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: HerefordImported.

Entry informationi

Entry nameiQ2KIC7_BOVIN
AccessioniPrimary (citable) accession number: Q2KIC7
Secondary accession number(s): F1N6Z5
Entry historyi
Integrated into UniProtKB/TrEMBL: March 7, 2006
Last sequence update: January 15, 2008
Last modified: July 6, 2016
This is version 91 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.