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Protein

Ribonuclease P protein subunit p29

Gene

POP4

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. May function with RPP38 to coordinate the nucleolar targeting and/or assembly of RNase P (By similarity).By similarity

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
Biological processtRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein subunit p29 (EC:3.1.26.5)
Gene namesi
Name:POP4
Synonyms:RPP29
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002366801 – 220Ribonuclease P protein subunit p29Add BLAST220

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei10PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ2KIB9.

Interactioni

Subunit structurei

Component of nuclear RNase P and RNase MRP ribonucleoproteins. RNase P consists of an RNA moiety and at least 8 protein subunits; POP1, RPP14, RPP20/POP7, RPP25, RPP29/POP4, RPP30, RPP38 and RPP40. RNase MRP consists of an RNA moiety and at least 9 protein subunits; POP1, RPP14, RPP20/POP7, RPP25, RPP29/POP4, RPP30, RPP38, RPP40, POP5 and RPP21. Interacts with RPP25 and POP5 (By similarity).By similarity

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000002876.

Structurei

3D structure databases

ProteinModelPortaliQ2KIB9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG4046. Eukaryota.
ENOG4111FUV. LUCA.
HOGENOMiHOG000007746.
HOVERGENiHBG002676.
InParanoidiQ2KIB9.
KOiK03538.

Family and domain databases

Gene3Di2.30.30.210. 1 hit.
InterProiView protein in InterPro
IPR002730. RNase_P/MRP_p29.
IPR016848. RNase_P/MRP_p29-subunit.
IPR036980. RNase_P/MRP_p29_sf.
IPR023534. Rof/RNase_P-like.
PfamiView protein in Pfam
PF01868. UPF0086. 1 hit.
PIRSFiPIRSF027081. RNase_P/MRP_p29_subunit. 1 hit.
SMARTiView protein in SMART
SM00538. POP4. 1 hit.
SUPFAMiSSF101744. SSF101744. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2KIB9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSVVYHAFS QKEAKELDVQ HSGAQRAEAF VRAFLKRSMP RMSQQALEDH
60 70 80 90 100
LQRKAVVLEY FTHRKQKEKR KKSKGLSAKQ RRELRLFDIK PEQQRYSLFL
110 120 130 140 150
PLHELWKQYI RDLCNGLKPD TQPQMIQAKL LKADLHGAIV SVTKSKCPSY
160 170 180 190 200
VGVTGILLQE TKHVFKIITK EDRLKVIPKL NCVFTVEIDG FISYIYGSKF
210 220
QLRSSERSAK KFKAKGTIDL
Length:220
Mass (Da):25,524
Last modified:March 7, 2006 - v1
Checksum:i0F9F42C93BD1D627
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC112695 mRNA. Translation: AAI12696.1.
RefSeqiNP_001106753.1. NM_001113282.2.
UniGeneiBt.21490.

Genome annotation databases

GeneIDi614870.
KEGGibta:614870.

Similar proteinsi

Entry informationi

Entry nameiRPP29_BOVIN
AccessioniPrimary (citable) accession number: Q2KIB9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: March 7, 2006
Last modified: October 25, 2017
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families