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Protein

DnaJ homolog subfamily C member 17

Gene

DNAJC17

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May negatively affect PAX8-induced thyroglobulin/TG transcription.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone, RNA-binding
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
DnaJ homolog subfamily C member 17
Gene namesi
Name:DNAJC17
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 10

Organism-specific databases

VGNCiVGNC:53574 DNAJC17

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002471171 – 304DnaJ homolog subfamily C member 17Add BLAST304

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei112PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ2KI83
PRIDEiQ2KI83

Expressioni

Gene expression databases

BgeeiENSBTAG00000013480

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000017926

Structurei

3D structure databases

ProteinModelPortaliQ2KI83
SMRiQ2KI83
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 76JPROSITE-ProRule annotationAdd BLAST66
Domaini178 – 249RRMPROSITE-ProRule annotationAdd BLAST72

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi113 – 117Poly-Glu5

Phylogenomic databases

eggNOGiKOG0691 Eukaryota
COG2214 LUCA
GeneTreeiENSGT00550000074688
HOGENOMiHOG000239711
HOVERGENiHBG062744
InParanoidiQ2KI83
KOiK09537
OMAiDSAQHRI
OrthoDBiEOG091G0L2J
TreeFamiTF321770

Family and domain databases

CDDicd06257 DnaJ, 1 hit
cd12429 RRM_DNAJC17, 1 hit
Gene3Di1.10.287.110, 1 hit
3.30.70.330, 1 hit
InterProiView protein in InterPro
IPR001623 DnaJ_domain
IPR034254 DNAJC17_RRM
IPR036869 J_dom_sf
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
PfamiView protein in Pfam
PF00226 DnaJ, 1 hit
PF00076 RRM_1, 1 hit
PRINTSiPR00625 JDOMAIN
SMARTiView protein in SMART
SM00271 DnaJ, 1 hit
SUPFAMiSSF46565 SSF46565, 1 hit
SSF54928 SSF54928, 1 hit
PROSITEiView protein in PROSITE
PS50076 DNAJ_2, 1 hit
PS50102 RRM, 1 hit

Sequencei

Sequence statusi: Complete.

Q2KI83-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVTKELLQM DLYALLGIEE KAEDKEVKKA YRQKALSCHP DKNPDNPRAA
60 70 80 90 100
ELFHQLSQAL EVLTDAAARA AYDKVRKAKK QAAERTQKLD ERRKKVKLDL
110 120 130 140 150
EARERQAQAL GSEEEEESGS ARTLEQEIER LREEGSRQLE EQQRLIREQI
160 170 180 190 200
RQEQEQRLTG MAKNPENKET PKLKLKWKSK KEAESQGGYS RDVLLQLFQK
210 220 230 240 250
YGEVLNLVLS SKKAGTAVVE FATVKAAELA VQNEVGLVDN PLKISWLEGR
260 270 280 290 300
PQSAMGHNHP GLSRGSVVSE RDYESLVMMR MRQAAERQQL IAQMQQEDQA

GQPT
Length:304
Mass (Da):34,572
Last modified:March 7, 2006 - v1
Checksum:i883BA9173B418790
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC112733 mRNA Translation: AAI12734.1
RefSeqiNP_001039741.1, NM_001046276.2
UniGeneiBt.46449

Genome annotation databases

EnsembliENSBTAT00000017926; ENSBTAP00000017926; ENSBTAG00000013480
GeneIDi524795
KEGGibta:524795

Similar proteinsi

Entry informationi

Entry nameiDJC17_BOVIN
AccessioniPrimary (citable) accession number: Q2KI83
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 25, 2006
Last sequence update: March 7, 2006
Last modified: May 23, 2018
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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