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Protein

40S ribosomal protein S27

Gene

RPS27

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Component of the small ribosomal subunit (By similarity). Required for proper rRNA processing and maturation of 18S rRNAs (By similarity).By similarity

Cofactori

Zn2+CuratedNote: Binds 1 zinc ion per subunit.Curated

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri38 – 60C4-typeSequence analysisAdd BLAST23

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein
LigandMetal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-BTA-141444. Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal.
R-BTA-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-BTA-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-BTA-2467813. Separation of Sister Chromatids.
R-BTA-2500257. Resolution of Sister Chromatid Cohesion.
R-BTA-5663220. RHO GTPases Activate Formins.
R-BTA-6791226. Major pathway of rRNA processing in the nucleolus and cytosol.
R-BTA-68877. Mitotic Prometaphase.
R-BTA-72649. Translation initiation complex formation.
R-BTA-72689. Formation of a pool of free 40S subunits.
R-BTA-72695. Formation of the ternary complex, and subsequently, the 43S complex.
R-BTA-72702. Ribosomal scanning and start codon recognition.
R-BTA-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-BTA-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-BTA-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S27
Gene namesi
Name:RPS27
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002403001 – 8440S ribosomal protein S27Add BLAST84

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei11PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ2KHT7.
PeptideAtlasiQ2KHT7.
PRIDEiQ2KHT7.

Expressioni

Gene expression databases

BgeeiENSBTAG00000013866.

Interactioni

Subunit structurei

Component of the small ribosomal subunit.By similarity

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000018414.

Structurei

3D structure databases

ProteinModelPortaliQ2KHT7.
SMRiQ2KHT7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri38 – 60C4-typeSequence analysisAdd BLAST23

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiKOG1779. Eukaryota.
COG2051. LUCA.
GeneTreeiENSGT00390000013514.
HOVERGENiHBG000252.
InParanoidiQ2KHT7.
KOiK02978.
OMAiCDNCSTV.
OrthoDBiEOG091G157G.
TreeFamiTF300265.

Family and domain databases

Gene3Di2.20.25.100. 1 hit.
HAMAPiMF_00371. Ribosomal_S27e. 1 hit.
InterProiView protein in InterPro
IPR000592. Ribosomal_S27e.
IPR023407. Ribosomal_S27e_Zn-bd_dom_sf.
IPR011332. Ribosomal_zn-bd.
PANTHERiPTHR11594. PTHR11594. 1 hit.
PfamiView protein in Pfam
PF01667. Ribosomal_S27e. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD004466. Ribosomal_S27e. 1 hit.
SUPFAMiSSF57829. SSF57829. 1 hit.
PROSITEiView protein in PROSITE
PS01168. RIBOSOMAL_S27E. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2KHT7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPLAKDLLHP SPEEEKRKHK KKRLVQSPNS YFMDVKCPGC YKITTVFSHA
60 70 80
QTVVLCVGCS TVLCQPTGGK ARLTEGCSFR RKQH
Length:84
Mass (Da):9,461
Last modified:January 23, 2007 - v3
Checksum:i242C4466AC8A8900
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti80R → G in ABC84249 (Ref. 1) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ347615 mRNA. Translation: ABC84249.1.
BC112887 mRNA. Translation: AAI12888.1.
RefSeqiNP_001091604.1. NM_001098135.2.
UniGeneiBt.2191.
Bt.65582.

Genome annotation databases

EnsembliENSBTAT00000018414; ENSBTAP00000018414; ENSBTAG00000013866.
GeneIDi615638.
KEGGibta:615638.

Similar proteinsi

Entry informationi

Entry nameiRS27_BOVIN
AccessioniPrimary (citable) accession number: Q2KHT7
Secondary accession number(s): A1XEE0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 13, 2006
Last sequence update: January 23, 2007
Last modified: November 22, 2017
This is version 101 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families