Reviewed, UniProtKB/Swiss-Prot Q2KHS5 (MOG2A_XENLA)

Names and origin

Protein names

Recommended name:
    2-acylglycerol O-acyltransferase 2-A
    EC=2.3.1.22
Alternative name(s):
    Monoacylglycerol O-acyltransferase 2-A
    Acyl CoA:monoacylglycerol acyltransferase 2-A
      Short name=MGAT2-A

Gene names

Name:

mogat2-A

Organism

Xenopus laevis (African clawed frog)

Taxonomic identifier

8355 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Amphibia › Batrachia › Anura › Mesobatrachia › Pipoidea › Pipidae › Xenopodinae › Xenopus › Xenopus

Protein attributes

Sequence length	335 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Catalyzes the formation of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA By similarity.
Catalytic activity	Acyl-CoA + 2-acylglycerol = CoA + diacylglycerol.
Pathway	Glycerolipid metabolism; triacylglycerol biosynthesis.
Subcellular location	Endoplasmic reticulum membrane; Multi-pass membrane protein By similarity.
Sequence similarities	Belongs to the diacylglycerol acyltransferase family.

Ontologies

Keywords
Biological process	Glycerol metabolism Lipid metabolism Lipid synthesis
Cellular component	Endoplasmic reticulum Membrane
Domain	Transmembrane
Molecular function	Acyltransferase Transferase
Gene Ontology (GO)
Biological process	glycerol metabolic process Inferred from electronic annotation. Source: UniProtKB-KW lipid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	endoplasmic reticulum Inferred from electronic annotation. Source: UniProtKB-KW integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	2-acylglycerol O-acyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 335	335	2-acylglycerol O-acyltransferase 2-A		PRO_0000249064
Regions
	Transmembrane	24 – 44	21	Potential
	Transmembrane	47 – 67	21	Potential

Sequences

	Sequence		Length	Mass (Da)
	Q2KHS5-1 [UniParc]. Last modified March 7, 2006. Version 1. Checksum: 1AB6A3F2D2EB23A8	FASTA	335	38,254
	10 20 30 40 50 60 MKIQFAPHNV PFERRLQTAA VLQWVFSFLA LAQTCILLFF VLLFTRFWII SVVYGVWWFL 70 80 90 100 110 120 DWDTPSKGGR RGEWLRRHVI WTYMKDYFPI TLVKTADLDP QQNYVVGSHP HGVLVAGAFT 130 140 150 160 170 180 NFCTEATGFH RLFPGITPYL LMLPLWFRAP FFRDYIMSGG LIPSDKDSAS YLLKNKAGGN 190 200 210 220 230 240 AVVIAVGGAP ESLDARPGAF TLLIKNRKGF VRLAILHGAS LVPVFSFGEN ELFDQVDNPR 250 260 270 280 290 300 GSWLRKIQEK LQKMMGVALP LFHARGVFQY SFGLIPYRKP IATIVGKPIR VEENPNPSSE 310 320 330 EVDKLHKIYM EELSKLFEEH KTKYNVPADK HLTFV

References

[1]	NIH - Xenopus Gene Collection (XGC) project Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Embryo.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BC112915 mRNA. Translation: AAI12916.1.
RefSeq	NP_001089961.1.
UniGene	Xl.53818
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	735031.
KEGG	xla:735031.
Organism-specific databases
Xenbase	XB-FEAT-5764956. mogat1.
Phylogenomic databases
HOVERGEN	Q2KHS5.
Enzyme and pathway databases
BRENDA	2.3.1.22. 648.
Family and domain databases
InterPro	IPR007130. DAGAT. [Graphical view]
PANTHER	PTHR12317. DAGAT. 1 hit.
Pfam	PF03982. DAGAT. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MOG2A_XENLA

Accession

Primary (citable) accession number: Q2KHS5

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 5, 2006
Last sequence update:	March 7, 2006
Last modified:	October 13, 2009
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

Xenopus annotation project