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Q2KDX6

- Q2KDX6_RHIEC

UniProt

Q2KDX6 - Q2KDX6_RHIEC

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Protein
Submitted name:

Probable sugar kinase protein

Gene

RHE_CH00135

Organism
Rhizobium etli (strain CFN 42 / ATCC 51251)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei215 – 2151ADPImported
Binding sitei277 – 2771ADP; via amide nitrogenImported

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi245 – 2506ADPImported

GO - Molecular functioni

  1. kinase activity Source: UniProtKB-KW
  2. nucleotide binding Source: UniProtKB-KW
  3. phosphotransferase activity, alcohol group as acceptor Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

KinaseSAAS annotationImported, Transferase

Keywords - Ligandi

Nucleotide-bindingImported

Enzyme and pathway databases

BioCyciRETL347834:GJJ0-136-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Probable sugar kinase proteinImported
Gene namesi
Ordered Locus Names:RHE_CH00135Imported
OrganismiRhizobium etli (strain CFN 42 / ATCC 51251)Imported
Taxonomic identifieri347834 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium
ProteomesiUP000001936: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi347834.RHE_CH00135.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4E3AX-ray1.63A/B1-330[»]
4JKSX-ray1.51A/B1-330[»]
4JKUX-ray1.51A/B1-330[»]
4K8CX-ray1.51A/B1-330[»]
4K8KX-ray1.50A/B1-330[»]
4K8PX-ray1.50A/B1-330[»]
4K8TX-ray1.70A/B1-330[»]
4K93X-ray1.50A/B1-330[»]
4K9CX-ray1.50A/B1-330[»]
4K9IX-ray1.70A/B1-330[»]
4KADX-ray1.70A/B1-330[»]
4KAHX-ray1.80A/B1-330[»]
4KALX-ray1.50A/B1-330[»]
4KANX-ray1.51A/B1-330[»]
4KBEX-ray1.80A/B1-330[»]
4LBGX-ray1.50A/B1-330[»]
4LBXX-ray1.70A/B1-330[»]
4LC4X-ray1.70A/B1-330[»]
4LCAX-ray1.50A/B1-330[»]
ProteinModelPortaliQ2KDX6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0524.
HOGENOMiHOG000235949.
OMAiFCVERHR.
OrthoDBiEOG6FV82S.

Family and domain databases

Gene3Di3.40.1190.20. 1 hit.
InterProiIPR002173. Carboh/pur_kinase_PfkB_CS.
IPR011611. PfkB_dom.
IPR029056. Ribokinase-like.
[Graphical view]
PfamiPF00294. PfkB. 1 hit.
[Graphical view]
SUPFAMiSSF53613. SSF53613. 1 hit.
PROSITEiPS00584. PFKB_KINASES_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2KDX6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTRFDVLTVG NAIVDIISRC NDQFLIDNQI TKAAMNLIDA ERAELLYSRM
60 70 80 90 100
GPALEASGGS AGNTAAGVAN LGGKAAYFGN VAADQLGDIF THDIRAQGVH
110 120 130 140 150
YQTKPKGAFP PTARSMIFVT EDGERSMNTY LGACVELGPE DVEADVVADA
160 170 180 190 200
KVTYFEGYLW DPPRAKEAIL DCARIAHQHG REMSMTLSDS FCVDRYRGEF
210 220 230 240 250
LDLMRSGKVD IVFANRQEAL SLYQTDDFEE ALNRIAADCK IAAVTMSENG
260 270 280 290 300
AVILKGRERY YVNAIRIREV VDTTGAGDLF ASGFLYGYTQ GRSLEDCGKL
310 320 330
GCLAAGIVIQ QIGPRPMTSL SEAAKQAGLI
Length:330
Mass (Da):35,739
Last modified:March 7, 2006 - v1
Checksum:iF539E20DAB47EB4B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000133 Genomic DNA. Translation: ABC88960.1.
RefSeqiWP_011423529.1. NC_007761.1.
YP_467687.1. NC_007761.1.

Genome annotation databases

EnsemblBacteriaiABC88960; ABC88960; RHE_CH00135.
GeneIDi3893107.
KEGGiret:RHE_CH00135.
PATRICi23081562. VBIRhiEtl108884_0467.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000133 Genomic DNA. Translation: ABC88960.1 .
RefSeqi WP_011423529.1. NC_007761.1.
YP_467687.1. NC_007761.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4E3A X-ray 1.63 A/B 1-330 [» ]
4JKS X-ray 1.51 A/B 1-330 [» ]
4JKU X-ray 1.51 A/B 1-330 [» ]
4K8C X-ray 1.51 A/B 1-330 [» ]
4K8K X-ray 1.50 A/B 1-330 [» ]
4K8P X-ray 1.50 A/B 1-330 [» ]
4K8T X-ray 1.70 A/B 1-330 [» ]
4K93 X-ray 1.50 A/B 1-330 [» ]
4K9C X-ray 1.50 A/B 1-330 [» ]
4K9I X-ray 1.70 A/B 1-330 [» ]
4KAD X-ray 1.70 A/B 1-330 [» ]
4KAH X-ray 1.80 A/B 1-330 [» ]
4KAL X-ray 1.50 A/B 1-330 [» ]
4KAN X-ray 1.51 A/B 1-330 [» ]
4KBE X-ray 1.80 A/B 1-330 [» ]
4LBG X-ray 1.50 A/B 1-330 [» ]
4LBX X-ray 1.70 A/B 1-330 [» ]
4LC4 X-ray 1.70 A/B 1-330 [» ]
4LCA X-ray 1.50 A/B 1-330 [» ]
ProteinModelPortali Q2KDX6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 347834.RHE_CH00135.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABC88960 ; ABC88960 ; RHE_CH00135 .
GeneIDi 3893107.
KEGGi ret:RHE_CH00135.
PATRICi 23081562. VBIRhiEtl108884_0467.

Phylogenomic databases

eggNOGi COG0524.
HOGENOMi HOG000235949.
OMAi FCVERHR.
OrthoDBi EOG6FV82S.

Enzyme and pathway databases

BioCyci RETL347834:GJJ0-136-MONOMER.

Family and domain databases

Gene3Di 3.40.1190.20. 1 hit.
InterProi IPR002173. Carboh/pur_kinase_PfkB_CS.
IPR011611. PfkB_dom.
IPR029056. Ribokinase-like.
[Graphical view ]
Pfami PF00294. PfkB. 1 hit.
[Graphical view ]
SUPFAMi SSF53613. SSF53613. 1 hit.
PROSITEi PS00584. PFKB_KINASES_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CFN 42 / ATCC 51251Imported.
  2. "CRYSTAL STRUCTURE OF probable sugar kinase protein from Rhizobium etli CFN 42."
    Malashkevich V.N., Bhosle R., Toro R., Hillerich B., Gizzi A., Garforth S., Kar A., Chan M.K., Lafluer J., Patel H., Matikainen B., Chamala S., Lim S., Celikgil A., Villegas G., Evans B., Zenchek W., Love J.
    , Fiser A., Khafizov K., Seidel R., Bonanno J.B., Almo S.C.
    Submitted (MAR-2012) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.63 ANGSTROMS).
  3. "Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with DMSO, NYSGRC Target 14306."
    Malashkevich V.N., Bhosle R., Toro R., Hillerich B., Gizzi A., Garforth S., Kar A., Chan M.K., Lafluer J., Patel H., Matikainen B., Chamala S., Lim S., Celikgil A., Villegas G., Evans B., Love J., Fiser A.
    , Khafizov K., Seidel R., Bonanno J.B., Almo S.C.
    Submitted (MAR-2013) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.51 ANGSTROMS).
  4. "Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with quinaldic acid, NYSGRC Target 14306."
    Malashkevich V.N., Bhosle R., Toro R., Hillerich B., Gizzi A., Garforth S., Kar A., Chan M.K., Lafluer J., Patel H., Matikainen B., Chamala S., Lim S., Celikgil A., Villegas G., Evans B., Love J., Fiser A.
    , Khafizov K., Seidel R., Bonanno J.B., Almo S.C.
    Submitted (MAR-2013) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.51 ANGSTROMS).
  5. "Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with 1-(4-methoxyphenyl)-1-cyclopropane and 2-aminoperimidine."
    Malashkevich V.N., Bhosle R., Toro R., Hillerich B., Gizzi A., Garforth S., Kar A., Chan M.K., Lafluer J., Patel H., Matikainen B., Chamala S., Lim S., Celikgil A., Villegas G., Evans B., Love J., Fiser A.
    , Khafizov K., Seidel R., Bonanno J.B., Almo S.C.
    Submitted (APR-2013) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.50 ANGSTROMS).
  6. "Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with 2-(2,5-dimethyl-1,3-thiazol-4-yl)acetic acid."
    Malashkevich V.N., Bhosle R., Toro R., Hillerich B., Gizzi A., Garforth S., Kar A., Chan M.K., Lafluer J., Patel H., Matikainen B., Chamala S., Lim S., Celikgil A., Villegas G., Evans B., Love J., Fiser A.
    , Khafizov K., Seidel R., Bonanno J.B., Almo S.C.
    Submitted (APR-2013) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.51 ANGSTROMS).
  7. "Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with 2-ethylbenzyl alcohol."
    Malashkevich V.N., Bhosle R., Toro R., Hillerich B., Gizzi A., Garforth S., Kar A., Chan M.K., Lafluer J., Patel H., Matikainen B., Chamala S., Lim S., Celikgil A., Villegas G., Evans B., Love J., Fiser A.
    , Khafizov K., Seidel R., Bonanno J.B., Almo S.C.
    Submitted (APR-2013) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.50 ANGSTROMS).
  8. "Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with 4-bromo-1H-pyrazole."
    Malashkevich V.N., Bhosle R., Toro R., Hillerich B., Gizzi A., Garforth S., Kar A., Chan M.K., Lafluer J., Patel H., Matikainen B., Chamala S., Lim S., Celikgil A., Villegas G., Evans B., Love J., Fiser A.
    , Khafizov K., Seidel R., Bonanno J.B., Almo S.C.
    Submitted (APR-2013) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS).
  9. "Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with ADP."
    Malashkevich V.N., Bhosle R., Toro R., Hillerich B., Gizzi A., Garforth S., Kar A., Chan M.K., Lafluer J., Patel H., Matikainen B., Chamala S., Lim S., Celikgil A., Villegas G., Evans B., Love J., Fiser A.
    , Khafizov K., Seidel R., Bonanno J.B., Almo S.C.
    Submitted (APR-2013) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.51 ANGSTROMS) IN COMPLEX WITH ADP.
  10. "Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with benzoguanamine."
    Malashkevich V.N., Bhosle R., Toro R., Hillerich B., Gizzi A., Garforth S., Kar A., Chan M.K., Lafluer J., Patel H., Matikainen B., Chamala S., Lim S., Celikgil A., Villegas G., Evans B., Love J., Fiser A.
    , Khafizov K., Seidel R., Bonanno J.B., Almo S.C.
    Submitted (APR-2013) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS).
  11. "Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with ethyl 3,4-diaminobenzoate."
    Malashkevich V.N., Bhosle R., Toro R., Hillerich B., Gizzi A., Garforth S., Kar A., Chan M.K., Lafluer J., Patel H., Matikainen B., Chamala S., Lim S., Celikgil A., Villegas G., Evans B., Love J., Fiser A.
    , Khafizov K., Seidel R., Bonanno J.B., Almo S.C.
    Submitted (APR-2013) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.70 ANGSTROMS).
  12. "CRYSTAL STRUCTURE OF probable sugar kinase protein from Rhizobium etli CFN 42 complexed with N-(HYDROXYMETHYL)BENZAMIDE and 4-METHYL-3,4-DIHYDRO-2H-1,4-BENZOXAZINE-7-CARBOXYLIC ACID."
    Malashkevich V.N., Bhosle R., Toro R., Hillerich B., Gizzi A., Garforth S., Kar A., Chan M.K., Lafluer J., Patel H., Matikainen B., Chamala S., Lim S., Celikgil A., Villegas G., Evans B., Love J., Fiser A.
    , Khafizov K., Seidel R., Bonanno J.B., Almo S.C.
    Submitted (APR-2013) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.50 ANGSTROMS).
  13. "CRYSTAL STRUCTURE OF probable sugar kinase protein from Rhizobium etli CFN 42 complexed with N-(HYDROXYMETHYL)BENZAMIDE."
    Malashkevich V.N., Bhosle R., Toro R., Hillerich B., Gizzi A., Garforth S., Kar A., Chan M.K., Lafluer J., Patel H., Matikainen B., Chamala S., Lim S., Celikgil A., Villegas G., Evans B., Love J., Fiser A.
    , Khafizov K., Seidel R., Bonanno J.B., Almo S.C.
    Submitted (APR-2013) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.50 ANGSTROMS).
  14. "Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with N1-(2.3-dihydro-1H-inden-5-yl)acetam."
    Malashkevich V.N., Bhosle R., Toro R., Hillerich B., Gizzi A., Garforth S., Kar A., Chan M.K., Lafluer J., Patel H., Matikainen B., Chamala S., Lim S., Celikgil A., Villegas G., Evans B., Love J., Fiser A.
    , Khafizov K., Seidel R., Bonanno J.B., Almo S.C.
    Submitted (APR-2013) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.70 ANGSTROMS).
  15. "CRYSTAL STRUCTURE OF probable sugar kinase protein from Rhizobium etli CFN 42 complexed with Norharmane."
    Malashkevich V.N., Bhosle R., Toro R., Hillerich B., Gizzi A., Garforth S., Kar A., Chan M.K., Lafluer J., Patel H., Matikainen B., Chamala S., Lim S., Celikgil A., Villegas G., Evans B., Love J., Fiser A.
    , Khafizov K., Seidel R., Bonanno J.B., Almo S.C.
    Submitted (APR-2013) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.70 ANGSTROMS).
  16. "Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with quinoline-3-carboxylic acid."
    Malashkevich V.N., Bhosle R., Toro R., Seidel R., Almo S.C.
    Submitted (APR-2013) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.50 ANGSTROMS).
  17. "Crystal structure of probable sugar kinase protein from Rhizobium Etli CFN 42 complexed with adenosine."
    Malashkevich V.N., Bhosle R., Toro R., Hillerich B., Gizzi A., Garforth S., Kar A., Chan M.K., Lafluer J., Patel H., Matikainen B., Chamala S., Lim S., Celikgil A., Villegas G., Evans B., Love J., Fiser A.
    , Khafizov K., Seidel R., Bonanno J.B., Almo S.C.
    Submitted (JUN-2013) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.50 ANGSTROMS).
  18. "Crystal structure of probable sugar kinase protein from Rhizobium Etli CFN 42 complexed with cytidine."
    Malashkevich V.N., Bhosle R., Toro R., Hillerich B., Gizzi A., Garforth S., Kar A., Chan M.K., Lafluer J., Patel H., Matikainen B., Chamala S., Lim S., Celikgil A., Villegas G., Evans B., Love J., Fiser A.
    , Khafizov K., Seidel R., Bonanno J.B., Almo S.C.
    Submitted (JUN-2013) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.70 ANGSTROMS).
  19. "Crystal structure of probable sugar kinase protein from Rhizobium Etli CFN 42 complexed with guanosine."
    Malashkevich v.n., Bhosle R., Toro R., Hillerich B., Gizzi A., Garforth S., Kar A., Chan M.K., Lafluer J., Patel H., Matikainen B., Chamala S., Lim S., Celikgil A., Villegas G., Evans B., Love J., Fiser A.
    , Khafizov K., Seidel R., Bonanno J.B., Almo S.C.
    Submitted (JUN-2013) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.70 ANGSTROMS).
  20. "Crystal structure of probable sugar kinase protein from Rhizobium Etli CFN 42 complexed with thymidine."
    Malashkevich V.N., Bhosle R., Toro R., Hillerich B., Gizzi A., Garforth S., Kar A., Chan M.K., Lafluer J., Patel H., Matikainen B., Chamala S., Lim S., Celikgil A., Villegas G., Evans B., Love J., Fiser A.
    , Khafizov K., Seidel R., Bonanno J.B., Almo S.C.
    Submitted (JUN-2013) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.50 ANGSTROMS).

Entry informationi

Entry nameiQ2KDX6_RHIEC
AccessioniPrimary (citable) accession number: Q2KDX6
Entry historyi
Integrated into UniProtKB/TrEMBL: March 7, 2006
Last sequence update: March 7, 2006
Last modified: November 26, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome, Reference proteomeImported

External Data

Dasty 3