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Q2KDX6

- Q2KDX6_RHIEC

UniProt

Q2KDX6 - Q2KDX6_RHIEC

Protein
Submitted name:

Probable sugar kinase protein

Gene

RHE_CH00135

Organism
Rhizobium etli (strain CFN 42 / ATCC 51251)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 56 (01 Oct 2014)
      Sequence version 1 (07 Mar 2006)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei215 – 2151ADPImported
    Binding sitei277 – 2771ADP; via amide nitrogenImported

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi245 – 2506ADPImported

    GO - Molecular functioni

    1. kinase activity Source: UniProtKB-KW
    2. metal ion binding Source: UniProtKB-KW
    3. nucleotide binding Source: UniProtKB-KW
    4. phosphotransferase activity, alcohol group as acceptor Source: InterPro

    Keywords - Molecular functioni

    KinaseSAAS annotationImported, Transferase

    Keywords - Ligandi

    Nucleotide-bindingImported

    Enzyme and pathway databases

    BioCyciRETL347834:GJJ0-136-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Probable sugar kinase proteinImported
    Gene namesi
    Ordered Locus Names:RHE_CH00135Imported
    OrganismiRhizobium etli (strain CFN 42 / ATCC 51251)Imported
    Taxonomic identifieri347834 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium
    ProteomesiUP000001936: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi347834.RHE_CH00135.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    4E3AX-ray1.63A/B1-330[»]
    4JKSX-ray1.51A/B1-330[»]
    4JKUX-ray1.51A/B1-330[»]
    4K8CX-ray1.51A/B1-330[»]
    4K8KX-ray1.50A/B1-330[»]
    4K8PX-ray1.50A/B1-330[»]
    4K8TX-ray1.70A/B1-330[»]
    4K93X-ray1.50A/B1-330[»]
    4K9CX-ray1.50A/B1-330[»]
    4K9IX-ray1.70A/B1-330[»]
    4KADX-ray1.70A/B1-330[»]
    4KAHX-ray1.80A/B1-330[»]
    4KALX-ray1.50A/B1-330[»]
    4KANX-ray1.51A/B1-330[»]
    4KBEX-ray1.80A/B1-330[»]
    4LBGX-ray1.50A/B1-330[»]
    4LBXX-ray1.70A/B1-330[»]
    4LC4X-ray1.70A/B1-330[»]
    4LCAX-ray1.50A/B1-330[»]
    ProteinModelPortaliQ2KDX6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiCOG0524.
    HOGENOMiHOG000235949.
    OMAiFCVERHR.
    OrthoDBiEOG6FV82S.

    Family and domain databases

    Gene3Di3.40.1190.20. 1 hit.
    InterProiIPR002173. Carboh/pur_kinase_PfkB_CS.
    IPR011611. PfkB_dom.
    IPR029056. Ribokinase-like.
    [Graphical view]
    PfamiPF00294. PfkB. 1 hit.
    [Graphical view]
    SUPFAMiSSF53613. SSF53613. 1 hit.
    PROSITEiPS00584. PFKB_KINASES_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q2KDX6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTRFDVLTVG NAIVDIISRC NDQFLIDNQI TKAAMNLIDA ERAELLYSRM    50
    GPALEASGGS AGNTAAGVAN LGGKAAYFGN VAADQLGDIF THDIRAQGVH 100
    YQTKPKGAFP PTARSMIFVT EDGERSMNTY LGACVELGPE DVEADVVADA 150
    KVTYFEGYLW DPPRAKEAIL DCARIAHQHG REMSMTLSDS FCVDRYRGEF 200
    LDLMRSGKVD IVFANRQEAL SLYQTDDFEE ALNRIAADCK IAAVTMSENG 250
    AVILKGRERY YVNAIRIREV VDTTGAGDLF ASGFLYGYTQ GRSLEDCGKL 300
    GCLAAGIVIQ QIGPRPMTSL SEAAKQAGLI 330
    Length:330
    Mass (Da):35,739
    Last modified:March 7, 2006 - v1
    Checksum:iF539E20DAB47EB4B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000133 Genomic DNA. Translation: ABC88960.1.
    RefSeqiYP_467687.1. NC_007761.1.

    Genome annotation databases

    EnsemblBacteriaiABC88960; ABC88960; RHE_CH00135.
    GeneIDi3893107.
    KEGGiret:RHE_CH00135.
    PATRICi23081562. VBIRhiEtl108884_0467.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000133 Genomic DNA. Translation: ABC88960.1 .
    RefSeqi YP_467687.1. NC_007761.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    4E3A X-ray 1.63 A/B 1-330 [» ]
    4JKS X-ray 1.51 A/B 1-330 [» ]
    4JKU X-ray 1.51 A/B 1-330 [» ]
    4K8C X-ray 1.51 A/B 1-330 [» ]
    4K8K X-ray 1.50 A/B 1-330 [» ]
    4K8P X-ray 1.50 A/B 1-330 [» ]
    4K8T X-ray 1.70 A/B 1-330 [» ]
    4K93 X-ray 1.50 A/B 1-330 [» ]
    4K9C X-ray 1.50 A/B 1-330 [» ]
    4K9I X-ray 1.70 A/B 1-330 [» ]
    4KAD X-ray 1.70 A/B 1-330 [» ]
    4KAH X-ray 1.80 A/B 1-330 [» ]
    4KAL X-ray 1.50 A/B 1-330 [» ]
    4KAN X-ray 1.51 A/B 1-330 [» ]
    4KBE X-ray 1.80 A/B 1-330 [» ]
    4LBG X-ray 1.50 A/B 1-330 [» ]
    4LBX X-ray 1.70 A/B 1-330 [» ]
    4LC4 X-ray 1.70 A/B 1-330 [» ]
    4LCA X-ray 1.50 A/B 1-330 [» ]
    ProteinModelPortali Q2KDX6.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 347834.RHE_CH00135.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABC88960 ; ABC88960 ; RHE_CH00135 .
    GeneIDi 3893107.
    KEGGi ret:RHE_CH00135.
    PATRICi 23081562. VBIRhiEtl108884_0467.

    Phylogenomic databases

    eggNOGi COG0524.
    HOGENOMi HOG000235949.
    OMAi FCVERHR.
    OrthoDBi EOG6FV82S.

    Enzyme and pathway databases

    BioCyci RETL347834:GJJ0-136-MONOMER.

    Family and domain databases

    Gene3Di 3.40.1190.20. 1 hit.
    InterProi IPR002173. Carboh/pur_kinase_PfkB_CS.
    IPR011611. PfkB_dom.
    IPR029056. Ribokinase-like.
    [Graphical view ]
    Pfami PF00294. PfkB. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53613. SSF53613. 1 hit.
    PROSITEi PS00584. PFKB_KINASES_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CFN 42 / ATCC 51251Imported.
    2. "CRYSTAL STRUCTURE OF probable sugar kinase protein from Rhizobium etli CFN 42."
      Malashkevich V.N., Bhosle R., Toro R., Hillerich B., Gizzi A., Garforth S., Kar A., Chan M.K., Lafluer J., Patel H., Matikainen B., Chamala S., Lim S., Celikgil A., Villegas G., Evans B., Zenchek W., Love J.
      , Fiser A., Khafizov K., Seidel R., Bonanno J.B., Almo S.C.
      Submitted (MAR-2012) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (1.63 ANGSTROMS).
    3. "Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with DMSO, NYSGRC Target 14306."
      Malashkevich V.N., Bhosle R., Toro R., Hillerich B., Gizzi A., Garforth S., Kar A., Chan M.K., Lafluer J., Patel H., Matikainen B., Chamala S., Lim S., Celikgil A., Villegas G., Evans B., Love J., Fiser A.
      , Khafizov K., Seidel R., Bonanno J.B., Almo S.C.
      Submitted (MAR-2013) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (1.51 ANGSTROMS).
    4. "Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with quinaldic acid, NYSGRC Target 14306."
      Malashkevich V.N., Bhosle R., Toro R., Hillerich B., Gizzi A., Garforth S., Kar A., Chan M.K., Lafluer J., Patel H., Matikainen B., Chamala S., Lim S., Celikgil A., Villegas G., Evans B., Love J., Fiser A.
      , Khafizov K., Seidel R., Bonanno J.B., Almo S.C.
      Submitted (MAR-2013) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (1.51 ANGSTROMS).
    5. "Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with 1-(4-methoxyphenyl)-1-cyclopropane and 2-aminoperimidine."
      Malashkevich V.N., Bhosle R., Toro R., Hillerich B., Gizzi A., Garforth S., Kar A., Chan M.K., Lafluer J., Patel H., Matikainen B., Chamala S., Lim S., Celikgil A., Villegas G., Evans B., Love J., Fiser A.
      , Khafizov K., Seidel R., Bonanno J.B., Almo S.C.
      Submitted (APR-2013) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (1.50 ANGSTROMS).
    6. "Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with 2-(2,5-dimethyl-1,3-thiazol-4-yl)acetic acid."
      Malashkevich V.N., Bhosle R., Toro R., Hillerich B., Gizzi A., Garforth S., Kar A., Chan M.K., Lafluer J., Patel H., Matikainen B., Chamala S., Lim S., Celikgil A., Villegas G., Evans B., Love J., Fiser A.
      , Khafizov K., Seidel R., Bonanno J.B., Almo S.C.
      Submitted (APR-2013) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (1.51 ANGSTROMS).
    7. "Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with 2-ethylbenzyl alcohol."
      Malashkevich V.N., Bhosle R., Toro R., Hillerich B., Gizzi A., Garforth S., Kar A., Chan M.K., Lafluer J., Patel H., Matikainen B., Chamala S., Lim S., Celikgil A., Villegas G., Evans B., Love J., Fiser A.
      , Khafizov K., Seidel R., Bonanno J.B., Almo S.C.
      Submitted (APR-2013) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (1.50 ANGSTROMS).
    8. "Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with 4-bromo-1H-pyrazole."
      Malashkevich V.N., Bhosle R., Toro R., Hillerich B., Gizzi A., Garforth S., Kar A., Chan M.K., Lafluer J., Patel H., Matikainen B., Chamala S., Lim S., Celikgil A., Villegas G., Evans B., Love J., Fiser A.
      , Khafizov K., Seidel R., Bonanno J.B., Almo S.C.
      Submitted (APR-2013) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS).
    9. "Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with ADP."
      Malashkevich V.N., Bhosle R., Toro R., Hillerich B., Gizzi A., Garforth S., Kar A., Chan M.K., Lafluer J., Patel H., Matikainen B., Chamala S., Lim S., Celikgil A., Villegas G., Evans B., Love J., Fiser A.
      , Khafizov K., Seidel R., Bonanno J.B., Almo S.C.
      Submitted (APR-2013) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (1.51 ANGSTROMS) IN COMPLEX WITH ADP.
    10. "Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with benzoguanamine."
      Malashkevich V.N., Bhosle R., Toro R., Hillerich B., Gizzi A., Garforth S., Kar A., Chan M.K., Lafluer J., Patel H., Matikainen B., Chamala S., Lim S., Celikgil A., Villegas G., Evans B., Love J., Fiser A.
      , Khafizov K., Seidel R., Bonanno J.B., Almo S.C.
      Submitted (APR-2013) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS).
    11. "Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with ethyl 3,4-diaminobenzoate."
      Malashkevich V.N., Bhosle R., Toro R., Hillerich B., Gizzi A., Garforth S., Kar A., Chan M.K., Lafluer J., Patel H., Matikainen B., Chamala S., Lim S., Celikgil A., Villegas G., Evans B., Love J., Fiser A.
      , Khafizov K., Seidel R., Bonanno J.B., Almo S.C.
      Submitted (APR-2013) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (1.70 ANGSTROMS).
    12. "CRYSTAL STRUCTURE OF probable sugar kinase protein from Rhizobium etli CFN 42 complexed with N-(HYDROXYMETHYL)BENZAMIDE and 4-METHYL-3,4-DIHYDRO-2H-1,4-BENZOXAZINE-7-CARBOXYLIC ACID."
      Malashkevich V.N., Bhosle R., Toro R., Hillerich B., Gizzi A., Garforth S., Kar A., Chan M.K., Lafluer J., Patel H., Matikainen B., Chamala S., Lim S., Celikgil A., Villegas G., Evans B., Love J., Fiser A.
      , Khafizov K., Seidel R., Bonanno J.B., Almo S.C.
      Submitted (APR-2013) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (1.50 ANGSTROMS).
    13. "CRYSTAL STRUCTURE OF probable sugar kinase protein from Rhizobium etli CFN 42 complexed with N-(HYDROXYMETHYL)BENZAMIDE."
      Malashkevich V.N., Bhosle R., Toro R., Hillerich B., Gizzi A., Garforth S., Kar A., Chan M.K., Lafluer J., Patel H., Matikainen B., Chamala S., Lim S., Celikgil A., Villegas G., Evans B., Love J., Fiser A.
      , Khafizov K., Seidel R., Bonanno J.B., Almo S.C.
      Submitted (APR-2013) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (1.50 ANGSTROMS).
    14. "Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with N1-(2.3-dihydro-1H-inden-5-yl)acetam."
      Malashkevich V.N., Bhosle R., Toro R., Hillerich B., Gizzi A., Garforth S., Kar A., Chan M.K., Lafluer J., Patel H., Matikainen B., Chamala S., Lim S., Celikgil A., Villegas G., Evans B., Love J., Fiser A.
      , Khafizov K., Seidel R., Bonanno J.B., Almo S.C.
      Submitted (APR-2013) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (1.70 ANGSTROMS).
    15. "CRYSTAL STRUCTURE OF probable sugar kinase protein from Rhizobium etli CFN 42 complexed with Norharmane."
      Malashkevich V.N., Bhosle R., Toro R., Hillerich B., Gizzi A., Garforth S., Kar A., Chan M.K., Lafluer J., Patel H., Matikainen B., Chamala S., Lim S., Celikgil A., Villegas G., Evans B., Love J., Fiser A.
      , Khafizov K., Seidel R., Bonanno J.B., Almo S.C.
      Submitted (APR-2013) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (1.70 ANGSTROMS).
    16. "Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with quinoline-3-carboxylic acid."
      Malashkevich V.N., Bhosle R., Toro R., Seidel R., Almo S.C.
      Submitted (APR-2013) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (1.50 ANGSTROMS).
    17. "Crystal structure of probable sugar kinase protein from Rhizobium Etli CFN 42 complexed with adenosine."
      Malashkevich V.N., Bhosle R., Toro R., Hillerich B., Gizzi A., Garforth S., Kar A., Chan M.K., Lafluer J., Patel H., Matikainen B., Chamala S., Lim S., Celikgil A., Villegas G., Evans B., Love J., Fiser A.
      , Khafizov K., Seidel R., Bonanno J.B., Almo S.C.
      Submitted (JUN-2013) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (1.50 ANGSTROMS).
    18. "Crystal structure of probable sugar kinase protein from Rhizobium Etli CFN 42 complexed with cytidine."
      Malashkevich V.N., Bhosle R., Toro R., Hillerich B., Gizzi A., Garforth S., Kar A., Chan M.K., Lafluer J., Patel H., Matikainen B., Chamala S., Lim S., Celikgil A., Villegas G., Evans B., Love J., Fiser A.
      , Khafizov K., Seidel R., Bonanno J.B., Almo S.C.
      Submitted (JUN-2013) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (1.70 ANGSTROMS).
    19. "Crystal structure of probable sugar kinase protein from Rhizobium Etli CFN 42 complexed with guanosine."
      Malashkevich v.n., Bhosle R., Toro R., Hillerich B., Gizzi A., Garforth S., Kar A., Chan M.K., Lafluer J., Patel H., Matikainen B., Chamala S., Lim S., Celikgil A., Villegas G., Evans B., Love J., Fiser A.
      , Khafizov K., Seidel R., Bonanno J.B., Almo S.C.
      Submitted (JUN-2013) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (1.70 ANGSTROMS).
    20. "Crystal structure of probable sugar kinase protein from Rhizobium Etli CFN 42 complexed with thymidine."
      Malashkevich V.N., Bhosle R., Toro R., Hillerich B., Gizzi A., Garforth S., Kar A., Chan M.K., Lafluer J., Patel H., Matikainen B., Chamala S., Lim S., Celikgil A., Villegas G., Evans B., Love J., Fiser A.
      , Khafizov K., Seidel R., Bonanno J.B., Almo S.C.
      Submitted (JUN-2013) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (1.50 ANGSTROMS).

    Entry informationi

    Entry nameiQ2KDX6_RHIEC
    AccessioniPrimary (citable) accession number: Q2KDX6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 7, 2006
    Last sequence update: March 7, 2006
    Last modified: October 1, 2014
    This is version 56 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported, Complete proteome, Reference proteomeImported

    External Data

    Dasty 3