Q2KDT9 (GLK_RHIEC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glucokinase
EC=2.7.1.2

Alternative name(s):
Glucose kinase

Gene names

Name:	glk
Ordered Locus Names:	RHE_CH00172

Organism

Rhizobium etli (strain CFN 42 / ATCC 51251) [Complete proteome] [HAMAP]

Taxonomic identifier

347834 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Rhizobium › Rhizobium etli

Protein attributes

Sequence length	341 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + D-glucose = ADP + D-glucose 6-phosphate. HAMAP-Rule MF_00524
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the bacterial glucokinase family.

Ontologies

Keywords
Biological process	Glycolysis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	glycolysis Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: HAMAP glucokinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 341	341	Glucokinase HAMAP-Rule MF_00524		PRO_0000268782
Regions
	Nucleotide binding	18 – 23	6	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	Q2KDT9 [UniParc]. Last modified March 7, 2006. Version 1. Checksum: 2311A70EE3F78920	FASTA	341	36,427
	10 20 30 40 50 60 MPKSNHSTAP LPFPILIGDI GGTNARFSIL TDAYAEPKQF PNVRTADFAT IDEAIQKGVL 70 80 90 100 110 120 DKTAVQPRSA ILAVAGPIND DEIPLTNCAW VVRPKTMIEG LGIEDVLVVN DFEAQALAIA 130 140 150 160 170 180 ALSDENRERI GSATGDMVAS RVVLGPGTGL GVGGLVHAQH TWIPVPGEGG HIDLGPRSKR 190 200 210 220 230 240 DYEIFPHIET IEGRVSAEQI LCGRGLVNLY NAICVVDGIQ PTMKDPADIT SHALDGSDKV 250 260 270 280 290 300 AVETVSLFAT YLGRVAGDMA MVFMARGGVY LSGGISQKII PALKKPEFRQ AFEDKAPHSA 310 320 330 340 LLRTIPTYVV THPLAALAGL SSYARMPANF GVSTEGRRWR R

References

[1]

"The partitioned Rhizobium etli genome: genetic and metabolic redundancy in seven interacting replicons." Gonzalez V., Santamaria R.I., Bustos P., Hernandez-Gonzalez I., Medrano-Soto A., Moreno-Hagelsieb G., Janga S.C., Ramirez M.A., Jimenez-Jacinto V., Collado-Vides J., Davila G. Proc. Natl. Acad. Sci. U.S.A. 103:3834-3839(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CFN 42 / ATCC 51251.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000133 Genomic DNA. Translation: ABC88997.1.
RefSeq	YP_467724.1. NC_007761.1.
3D structure databases
ProteinModelPortal	Q2KDT9.
ModBase	Search...
Protein-protein interaction databases
STRING	347834.RHE_CH00172.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABC88997; ABC88997; RHE_CH00172.
GeneID	3890910.
KEGG	ret:RHE_CH00172.
PATRIC	23081634. VBIRhiEtl108884_0503.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0837.
HOGENOM	HOG000274469.
KO	K00845.
OMA	DITSHAL.
ProtClustDB	PRK00292.
Enzyme and pathway databases
BioCyc	RETL347834:GJJ0-173-MONOMER.
Family and domain databases
HAMAP	MF_00524. Glucokinase.
InterPro	IPR003836. Glucokinase. [Graphical view]
Pfam	PF02685. Glucokinase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00749. glk. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLK_RHIEC

Accession

Primary (citable) accession number: Q2KDT9

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 12, 2006
Last sequence update:	March 7, 2006
Last modified:	May 1, 2013
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program