Q2KCH9 (CHER_RHIEC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable chemotaxis protein methyltransferase
EC=2.1.1.80

Gene names

Name:	cheRch1
Ordered Locus Names:	RHE_CH00641

Organism

Rhizobium etli (strain CFN 42 / ATCC 51251) [Complete proteome] [HAMAP]

Taxonomic identifier

347834 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Rhizobium

Protein attributes

Sequence length	268 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Function	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP Potential.
Catalytic activity	S-adenosyl-L-methionine + protein L-glutamate = S-adenosyl-L-homocysteine + protein L-glutamate methyl ester.
Sequence similarities	Contains 1 cheR-type methyltransferase domain.

Ontologies

Keywords
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	protein-glutamate O-methyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 268	268	Probable chemotaxis protein methyltransferase		PRO_0000239042
Regions
	Domain	1 – 262	262	CheR-type methyltransferase
	Region	188 – 189	2	S-adenosyl-L-methionine binding By similarity
	Region	205 – 206	2	S-adenosyl-L-methionine binding By similarity
Sites
	Binding site	60	1	S-adenosyl-L-methionine By similarity
	Binding site	62	1	S-adenosyl-L-methionine By similarity
	Binding site	66	1	S-adenosyl-L-methionine By similarity
	Binding site	104	1	S-adenosyl-L-methionine By similarity
	Binding site	130	1	S-adenosyl-L-methionine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q2KCH9 [UniParc]. Last modified March 7, 2006. Version 1. Checksum: 170047C8E82BC516	FASTA	268	30,638
	10 20 30 40 50 60 MIYSDAGIFL NETKASLVYS RLSKHIRNLG LSGFREYCEL VASPAGAAAR REMLSHLTTN 70 80 90 100 110 120 FTRFFRENHH FEHLRDHVLP ELLQRARSGG RVRIWSAASS DGQEPYSIAL TVLSLMPNVA 130 140 150 160 170 180 DYDFKILATD IDPKILAIAR AGAYDESALE TVSPAMRKQW FSEVEVQGRR KFQVDDRVKR 190 200 210 220 230 240 LITYNELNLM AQWPFKGKFD VIFCRNVVIY FDEPTQMKIW QRFAGLLPEG GHLYIGHSER 250 260 VSGEAKHVFD NIGITTYRYT TKGLGRKA

References

[1]

"The partitioned Rhizobium etli genome: genetic and metabolic redundancy in seven interacting replicons." Gonzalez V., Santamaria R.I., Bustos P., Hernandez-Gonzalez I., Medrano-Soto A., Moreno-Hagelsieb G., Janga S.C., Ramirez M.A., Jimenez-Jacinto V., Collado-Vides J., Davila G. Proc. Natl. Acad. Sci. U.S.A. 103:3834-3839(2006) [PubMed: 16505379] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CFN 42 / ATCC 51251.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000133 Genomic DNA. Translation: ABC89457.1.
RefSeq	YP_468184.1. NC_007761.1.
3D structure databases
ProteinModelPortal	Q2KCH9.
ModBase	Search...
Protein-protein interaction databases
STRING	Q2KCH9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3892464.
GenomeReviews	Gene locus RHE_CH00641 in contig CP000133_GR.
KEGG	ret:RHE_CH00641.
PATRIC	23082599. VBIRhiEtl108884_0978.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1352.
HOGENOM	HBG661948.
OMA	NELNLMA.
PhylomeDB	Q2KCH9.
ProtClustDB	CLSK881448.
Family and domain databases
InterPro	IPR022642. CheR_C. IPR000780. CheR_MeTrfase. IPR022641. CheR_N. [Graphical view]
Gene3D	G3DSA:1.10.155.10. CheR_N. 1 hit.
KO	K00575.
Pfam	PF01739. CheR. 1 hit. PF03705. CheR_N. 1 hit. [Graphical view]
PRINTS	PR00996. CHERMTFRASE.
SMART	SM00138. MeTrc. 1 hit. [Graphical view]
SUPFAM	SSF47757. CheR_mtfrase. 1 hit.
PROSITE	PS50123. CHER. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CHER_RHIEC

Accession

Primary (citable) accession number: Q2KCH9

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2006
Last sequence update:	March 7, 2006
Last modified:	January 25, 2012
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program