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Q2KAA1

- Q2KAA1_RHIEC

UniProt

Q2KAA1 - Q2KAA1_RHIEC

Protein

Alanine racemase

Gene

alr

Organism
Rhizobium etli (strain CFN 42 / ATCC 51251)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 68 (01 Oct 2014)
      Sequence version 1 (07 Mar 2006)
      Previous versions | rss
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    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei92 – 921SubstrateUniRule annotation
    Active sitei214 – 2141Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei273 – 2731Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciRETL347834:GJJ0-1441-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Name:alrImported
    Ordered Locus Names:RHE_CH01432Imported
    OrganismiRhizobium etli (strain CFN 42 / ATCC 51251)Imported
    Taxonomic identifieri347834 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium
    ProteomesiUP000001936: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi347834.RHE_CH01432.

    Structurei

    3D structure databases

    ProteinModelPortaliQ2KAA1.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0787.
    HOGENOMiHOG000031445.
    KOiK01775.
    OMAiITIKSHV.
    OrthoDBiEOG6PP9NJ.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q2KAA1-1 [UniParc]FASTAAdd to Basket

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    MGIEDAGEAL YLAGARDFFV ATVDEGVTLR LYAPEARIFV LSGIWPGTER    50
    RFFDNDLVPV ISSDEQFAFW MAVLADYGDY PCALHVDTGF NRLGLHIDDA 100
    IALADDVSRP ASFAPVLVMS HLACGDDPSH LMNRQQLESF RKVTAAYEGI 150
    DSSLAASAGI FLGEDYHFDL TRPGIALYGG EAVCGVTNPM RPVATTEARI 200
    IQVRTVKAGE TVSYGRALQL HRDSRLAIVS AGYADGYMRS QSSGGVPLRQ 250
    AVPQGGQGFI AGHKVPVAGR ITMDLTIFDV TDLPENAVRA GDYVELFGKN 300
    MALDDVARAA GTIGYEILTS MGLRHERRYV AEE 333
    Length:333
    Mass (Da):36,045
    Last modified:March 7, 2006 - v1
    Checksum:i06264F49BC1F36E3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000133 Genomic DNA. Translation: ABC90235.1.
    RefSeqiYP_468962.1. NC_007761.1.

    Genome annotation databases

    EnsemblBacteriaiABC90235; ABC90235; RHE_CH01432.
    GeneIDi3892671.
    KEGGiret:RHE_CH01432.
    PATRICi23084269. VBIRhiEtl108884_1806.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000133 Genomic DNA. Translation: ABC90235.1 .
    RefSeqi YP_468962.1. NC_007761.1.

    3D structure databases

    ProteinModelPortali Q2KAA1.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 347834.RHE_CH01432.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABC90235 ; ABC90235 ; RHE_CH01432 .
    GeneIDi 3892671.
    KEGGi ret:RHE_CH01432.
    PATRICi 23084269. VBIRhiEtl108884_1806.

    Phylogenomic databases

    eggNOGi COG0787.
    HOGENOMi HOG000031445.
    KOi K01775.
    OMAi ITIKSHV.
    OrthoDBi EOG6PP9NJ.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci RETL347834:GJJ0-1441-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CFN 42 / ATCC 51251Imported.

    Entry informationi

    Entry nameiQ2KAA1_RHIEC
    AccessioniPrimary (citable) accession number: Q2KAA1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 7, 2006
    Last sequence update: March 7, 2006
    Last modified: October 1, 2014
    This is version 68 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3