Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q2K813

- GCSP_RHIEC

UniProt

Q2K813 - GCSP_RHIEC

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Glycine dehydrogenase (decarboxylating)

Gene

gcvP

Organism
Rhizobium etli (strain CFN 42 / ATCC 51251)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO2 is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.UniRule annotation

Catalytic activityi

Glycine + [glycine-cleavage complex H protein]-N(6)-lipoyl-L-lysine = [glycine-cleavage complex H protein]-S-aminomethyl-N(6)-dihydrolipoyl-L-lysine + CO2.UniRule annotation

Cofactori

Pyridoxal phosphate.UniRule annotation

GO - Molecular functioni

  1. glycine dehydrogenase (decarboxylating) activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glycine decarboxylation via glycine cleavage system Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

Pyridoxal phosphate

Enzyme and pathway databases

BioCyciRETL347834:GJJ0-2254-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycine dehydrogenase (decarboxylating)UniRule annotation (EC:1.4.4.2UniRule annotation)
Alternative name(s):
Glycine cleavage system P-proteinUniRule annotation
Glycine decarboxylaseUniRule annotation
Glycine dehydrogenase (aminomethyl-transferring)UniRule annotation
Gene namesi
Name:gcvPUniRule annotation
Ordered Locus Names:RHE_CH02243
OrganismiRhizobium etli (strain CFN 42 / ATCC 51251)
Taxonomic identifieri347834 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium
ProteomesiUP000001936: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 954954Glycine dehydrogenase (decarboxylating)PRO_1000045599Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei704 – 7041N6-(pyridoxal phosphate)lysineUniRule annotation

Proteomic databases

PRIDEiQ2K813.

Interactioni

Subunit structurei

The glycine cleavage system is composed of four proteins: P, T, L and H.UniRule annotation

Protein-protein interaction databases

STRINGi347834.RHE_CH02243.

Structurei

3D structure databases

ProteinModelPortaliQ2K813.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GcvP family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1003.
KOiK00281.
OMAiTAYLTHP.
OrthoDBiEOG6HMXDX.

Family and domain databases

Gene3Di3.40.640.10. 2 hits.
HAMAPiMF_00711. GcvP.
InterProiIPR020580. GDC-P_N.
IPR020581. GDC_P.
IPR003437. GDC_P_homo.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11773. PTHR11773. 1 hit.
PfamiPF02347. GDC-P. 2 hits.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 3 hits.
TIGRFAMsiTIGR00461. gcvP. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2K813-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTTPTEFQFT DYQPYDFANR RHIGPSPAEM AEMLKVIGYN SLEGLIDATL
60 70 80 90 100
PPAIRQKAPL VWGAPMTERE ALDKLRETAN KNKVLVSLIG QGYYGTITPP
110 120 130 140 150
VIQRNILENP AWYTAYTPYQ PEISQGRLEA LLNYQTMVCD LTGLDIANAS
160 170 180 190 200
LLDEATAAAE GMAMAERVAK SKAKAFFVDA DCHPQTIALI RTRAEPLGWS
210 220 230 240 250
VIVGNPFTDL DPVDVFGAIF QYPGTHGHVH DFTGLIARLH QAGAISVVAA
260 270 280 290 300
DILALTLLKS PGEMGADIAV GSSQRFGVPV GYGGPHAAFM AVRDAIKRAM
310 320 330 340 350
PGRLVGVSVD ARGNRAYRLS LQTREQHIRR EKATSNICTA QVLLAVMASM
360 370 380 390 400
YAVFHGPDGI KAIAQQVHQK AVLMAKGLEK LGYKVEPESF FDTITVDVGH
410 420 430 440 450
MQGLILRAAV AEGVNLRKVG ETKIGMSLDE RTRPATLEAV WRAFGGNFTI
460 470 480 490 500
ADFEPSYRLP KALLRTSEYL SHPIFHMNRA ESEMTRYIRR LSDRDLALDR
510 520 530 540 550
AMIPLGSCTM KLNATAEMLP ITWPEFSDIH PFVPADQALG YREMLDDLTE
560 570 580 590 600
KLCAVTGYDA FSMQPNSGAQ GEYAGLLTIR NYHIANGEGH RDVCLIPTSA
610 620 630 640 650
HGTNPASAQM VGMKVVVVKV RENGDIDMED FRAKAEEHAA NLSCCMITYP
660 670 680 690 700
STHGVFEETV KEICELVHKH GGQVYLDGAN MNAMVGLSRP GDIGSDVSHL
710 720 730 740 750
NLHKTFCIPH GGGGPGMGPI GVKAHLAPHL PGHPETDGRP GAVSAAPFGS
760 770 780 790 800
ASILPISWSY CLMMGGEGLT QATKVAILNA NYIATRLKGA YNVLYKSKTG
810 820 830 840 850
RVAHECIIDT RPLVDSSGVT VDDVAKRLID CGFHAPTMSW PVAGTLMIEP
860 870 880 890 900
TESETKAELD RFCEAMLAIR EEARAIEDGR MDKTNNPLKN APHTVEDLVG
910 920 930 940 950
EWDRPYSREQ ACFPPGAFRV DKYWSPVNRV DNVYGDRNLI CTCPPVESYA

EAAE
Length:954
Mass (Da):104,034
Last modified:March 7, 2006 - v1
Checksum:i50338D5932DA1EC8
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000133 Genomic DNA. Translation: ABC91023.1.
RefSeqiWP_011425504.1. NC_007761.1.
YP_469750.1. NC_007761.1.

Genome annotation databases

EnsemblBacteriaiABC91023; ABC91023; RHE_CH02243.
GeneIDi3890670.
KEGGiret:RHE_CH02243.
PATRICi23086012. VBIRhiEtl108884_2659.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000133 Genomic DNA. Translation: ABC91023.1 .
RefSeqi WP_011425504.1. NC_007761.1.
YP_469750.1. NC_007761.1.

3D structure databases

ProteinModelPortali Q2K813.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 347834.RHE_CH02243.

Proteomic databases

PRIDEi Q2K813.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABC91023 ; ABC91023 ; RHE_CH02243 .
GeneIDi 3890670.
KEGGi ret:RHE_CH02243.
PATRICi 23086012. VBIRhiEtl108884_2659.

Phylogenomic databases

eggNOGi COG1003.
KOi K00281.
OMAi TAYLTHP.
OrthoDBi EOG6HMXDX.

Enzyme and pathway databases

BioCyci RETL347834:GJJ0-2254-MONOMER.

Family and domain databases

Gene3Di 3.40.640.10. 2 hits.
HAMAPi MF_00711. GcvP.
InterProi IPR020580. GDC-P_N.
IPR020581. GDC_P.
IPR003437. GDC_P_homo.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view ]
PANTHERi PTHR11773. PTHR11773. 1 hit.
Pfami PF02347. GDC-P. 2 hits.
[Graphical view ]
SUPFAMi SSF53383. SSF53383. 3 hits.
TIGRFAMsi TIGR00461. gcvP. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CFN 42 / ATCC 51251.

Entry informationi

Entry nameiGCSP_RHIEC
AccessioniPrimary (citable) accession number: Q2K813
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: March 7, 2006
Last modified: October 1, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3