ID   Q2K6F4_RHIEC            Unreviewed;       304 AA.
AC   Q2K6F4;
DT   07-MAR-2006, integrated into UniProtKB/TrEMBL.
DT   07-MAR-2006, sequence version 1.
DT   27-MAR-2024, entry version 98.
DE   SubName: Full=Adenylate cyclase protein {ECO:0000313|EMBL:ABC91582.1};
GN   Name=cyaJ {ECO:0000313|EMBL:ABC91582.1};
GN   OrderedLocusNames=RHE_CH02814 {ECO:0000313|EMBL:ABC91582.1};
OS   Rhizobium etli (strain CFN 42 / ATCC 51251).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX   NCBI_TaxID=347834 {ECO:0000313|EMBL:ABC91582.1, ECO:0000313|Proteomes:UP000001936};
RN   [1] {ECO:0000313|EMBL:ABC91582.1, ECO:0000313|Proteomes:UP000001936}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CFN 42 / ATCC 51251 {ECO:0000313|Proteomes:UP000001936};
RX   PubMed=16505379; DOI=10.1073/pnas.0508502103;
RA   Gonzalez V., Santamaria R.I., Bustos P., Hernandez-Gonzalez I.,
RA   Medrano-Soto A., Moreno-Hagelsieb G., Janga S.C., Ramirez M.A.,
RA   Jimenez-Jacinto V., Collado-Vides J., Davila G.;
RT   "The partitioned Rhizobium etli genome: genetic and metabolic redundancy in
RT   seven interacting replicons.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:3834-3839(2006).
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DR   EMBL; CP000133; ABC91582.1; -; Genomic_DNA.
DR   RefSeq; WP_011426059.1; NC_007761.1.
DR   AlphaFoldDB; Q2K6F4; -.
DR   KEGG; ret:RHE_CH02814; -.
DR   eggNOG; COG2114; Bacteria.
DR   HOGENOM; CLU_924011_0_0_5; -.
DR   OrthoDB; 9807521at2; -.
DR   Proteomes; UP000001936; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR   PANTHER; PTHR43081:SF1; PH-SENSITIVE ADENYLATE CYCLASE RV1264; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001936};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        210..227
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        233..250
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        262..279
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        285..302
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          10..124
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
SQ   SEQUENCE   304 AA;  32798 MW;  34969D7015903FC5 CRC64;
     MSETRRKLTT IFCADVQDYT RLMGADEEGT LATLKRCRDA MAHLIESHGG RVVNTWGDGL
     IAEFPSVVEA VRAAVDTQNE LAGFNAGRPS NGRMLFRIGI NLGDVIVEGD DIYGDGVNIA
     ARLQTSASPG GIVISSTVYD QVRNKVAVGF EFLGPLTVKN VDEGVPSYAV KIGDGGDEAQ
     PAERPASVRP QPAAQVMAEA RPAAGYGRRL FSVLGVIAAV VVGINLLTWH AVFWARFPLL
     ALIVIAALAW NRDQARFDRR MVTLAITALG IIGINALTWN GTFWAVWPIL GIATMIGLRW
     AIRR
//