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Protein

C4-dicarboxylate transport protein

Gene

dctA

Organism
Rhizobium etli (strain CFN 42 / ATCC 51251)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Symport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
C4-dicarboxylate transport proteinUniRule annotation
Gene namesi
Name:dctAUniRule annotation
Ordered Locus Names:RHE_CH02971
OrganismiRhizobium etli (strain CFN 42 / ATCC 51251)
Taxonomic identifieri347834 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium
Proteomesi
  • UP000001936 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei17 – 37HelicalUniRule annotationAdd BLAST21
Transmembranei57 – 77HelicalUniRule annotationAdd BLAST21
Transmembranei92 – 112HelicalUniRule annotationAdd BLAST21
Transmembranei139 – 159HelicalUniRule annotationAdd BLAST21
Transmembranei161 – 181HelicalUniRule annotationAdd BLAST21
Transmembranei201 – 221HelicalUniRule annotationAdd BLAST21
Transmembranei234 – 254HelicalUniRule annotationAdd BLAST21
Transmembranei320 – 340HelicalUniRule annotationAdd BLAST21
Transmembranei368 – 388HelicalUniRule annotationAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000674601 – 443C4-dicarboxylate transport proteinAdd BLAST443

Interactioni

Protein-protein interaction databases

STRINGi347834.RHE_CH02971.

Structurei

3D structure databases

ProteinModelPortaliQ2K5Z8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105CK2. Bacteria.
COG1301. LUCA.
HOGENOMiHOG000208775.
KOiK11103.
OMAiIKMERLG.

Family and domain databases

Gene3Di1.10.3860.10. 1 hit.
HAMAPiMF_01300. C4_dicarb_transport. 1 hit.
InterProiIPR023954. C4_dicarb_transport.
IPR001991. Na-dicarboxylate_symporter.
IPR018107. Na-dicarboxylate_symporter_CS.
[Graphical view]
PANTHERiPTHR11958. PTHR11958. 1 hit.
PfamiPF00375. SDF. 1 hit.
[Graphical view]
PRINTSiPR00173. EDTRNSPORT.
SUPFAMiSSF118215. SSF118215. 1 hit.
PROSITEiPS00713. NA_DICARBOXYL_SYMP_1. 1 hit.
PS00714. NA_DICARBOXYL_SYMP_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2K5Z8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIAAPLDAVA DSKGKKPFYS HLYVQVLAAI AAGILLGHFY PELGTQLKPL
60 70 80 90 100
GDAFIKLVKM VIAPVIFLTV ATGIAGMSDL KKVGRVAGKA MLYFLTFSTL
110 120 130 140 150
ALVIGMIVAN VVQPGAGMNI DPASLDPKAV ATFADKAHEQ SIVGFLTNII
160 170 180 190 200
PTTIVGAFAD GDILQVLFFS VLFGIALAMV GEKGEQVVTF LNALTAPIFK
210 220 230 240 250
LVGILMKAAP IGAFGAMAFT IGKYGIGSIA NLAMLIGTFY ITSLLFVLVV
260 270 280 290 300
LGAVARYNGF SILALLRYIK EELLLVLGTS SSEAALPGLM NKMEKAGCKR
310 320 330 340 350
SVVGLVIPTG YSFNLDGTNI YMTLAALFIA QATGIQLSWG DQILLLLVAM
360 370 380 390 400
LSSKGAAGIT GAGFITLAAT LSVVPSVPVA GMALILGIDR FMSECRALTN
410 420 430 440
LVGNAVATIV VARWENELDT GQLARALGGE SEDTSTAGLQ PAE
Length:443
Mass (Da):46,111
Last modified:March 7, 2006 - v1
Checksum:i32ACFE55A8B61C8D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000133 Genomic DNA. Translation: ABC91738.1.
RefSeqiWP_011426214.1. NC_007761.1.

Genome annotation databases

EnsemblBacteriaiABC91738; ABC91738; RHE_CH02971.
GeneIDi24298655.
KEGGiret:RHE_CH02971.
PATRICi23087559. VBIRhiEtl108884_3430.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000133 Genomic DNA. Translation: ABC91738.1.
RefSeqiWP_011426214.1. NC_007761.1.

3D structure databases

ProteinModelPortaliQ2K5Z8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi347834.RHE_CH02971.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABC91738; ABC91738; RHE_CH02971.
GeneIDi24298655.
KEGGiret:RHE_CH02971.
PATRICi23087559. VBIRhiEtl108884_3430.

Phylogenomic databases

eggNOGiENOG4105CK2. Bacteria.
COG1301. LUCA.
HOGENOMiHOG000208775.
KOiK11103.
OMAiIKMERLG.

Family and domain databases

Gene3Di1.10.3860.10. 1 hit.
HAMAPiMF_01300. C4_dicarb_transport. 1 hit.
InterProiIPR023954. C4_dicarb_transport.
IPR001991. Na-dicarboxylate_symporter.
IPR018107. Na-dicarboxylate_symporter_CS.
[Graphical view]
PANTHERiPTHR11958. PTHR11958. 1 hit.
PfamiPF00375. SDF. 1 hit.
[Graphical view]
PRINTSiPR00173. EDTRNSPORT.
SUPFAMiSSF118215. SSF118215. 1 hit.
PROSITEiPS00713. NA_DICARBOXYL_SYMP_1. 1 hit.
PS00714. NA_DICARBOXYL_SYMP_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiDCTA_RHIEC
AccessioniPrimary (citable) accession number: Q2K5Z8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: March 7, 2006
Last modified: November 2, 2016
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.