Reviewed, UniProtKB/Swiss-Prot Q2K5M6 (ADEC1_RHIEC)

Names and origin

Protein names

Recommended name:
    Adenine deaminase 1
      Short name=Adenase 1
      Short name=Adenine aminase 1
    EC=3.5.4.2

Gene names

Name:	ade1
Synonyms:	adeC1
Ordered Locus Names:	RHE_CH03094

Organism

Rhizobium etli (strain CFN 42 / ATCC 51251) [Complete proteome] [HAMAP]

Taxonomic identifier

347834 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Rhizobium

Protein attributes

Sequence length	565 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Adenine + H2O = hypoxanthine + NH3. HAMAP MF_01518
Cofactor	Manganese By similarity.
Sequence similarities	Belongs to the adenine deaminase family.

Ontologies

Keywords
Ligand	Manganese
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	adenine catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	adenine deaminase activity Inferred from electronic annotation. Source: HAMAP manganese ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 565	565	Adenine deaminase 1 HAMAP MF_01518		PRO_0000292392

Sequences

	Sequence		Length	Mass (Da)
	Q2K5M6-1 [UniParc]. Last modified March 7, 2006. Version 1. Checksum: 10640A1EDCDECEC0	FASTA	565	60,708
	10 20 30 40 50 60 MTTKLERLID QGVGRIPADI VLKGGSFFDL VTGEIVRSDI AIGADRIVGT SGDYRGETEI 70 80 90 100 110 120 DISGRTVVPG FIDTHLHIES SLVTPHEFDR CVLPYGVTTA ICDPHEIANV LGTEGIEFFL 130 140 150 160 170 180 ESALETIMDI RVQLSSCVPA THLETAGADL PIERLLPFRD HPKVIGLAEF MNFPGVIHKD 190 200 210 220 230 240 SVCMAKLDAF QGGHIDGHAP LLSGNDLNGY LSAGIRTEHE CTSAAEALEK IRKGMHILVR 250 260 270 280 290 300 EGSVSKDLAA LIPIITERLS PYLALCTDDR NPLDIAEQGH LDHMIRTAMA SGVEPLAIYR 310 320 330 340 350 360 AASISAARAF GLRDRGLVAP GWRADLVVLD SLQSCRAEMV FSAGRRVSDA LFATRKPVAP 370 380 390 400 410 420 IGLDSVKARP VNAAHFGVPV AEGETSVIGV MPGKIITEHR RYRLPAKGNE TTVDLTNDII 430 440 450 460 470 480 KVAVIERHGK NGNHANGFVQ GFGLKKGAIA STVGHDSHNI CVVGVNEDDM AYAANRLGEI 490 500 510 520 530 540 KGGFVVVEDG KITGEIALPV AGLMSIEPYE TVRDTLHHLR QAALALGATL HEPFLQLAFL 550 560 PLPVIPHLKI SDRGMVDVDK FALIG

References

[1]

"The partitioned Rhizobium etli genome: genetic and metabolic redundancy in seven interacting replicons." Gonzalez V., Santamaria R.I., Bustos P., Hernandez-Gonzalez I., Medrano-Soto A., Moreno-Hagelsieb G., Janga S.C., Ramirez M.A., Jimenez-Jacinto V., Collado-Vides J., Davila G. Proc. Natl. Acad. Sci. U.S.A. 103:3834-3839(2006) [PubMed: 16505379] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000133 Genomic DNA. Translation: ABC91860.1.
RefSeq	YP_470587.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3892960.
GenomeReviews	Gene locus RHE_CH03094 in contig CP000133_GR.
KEGG	ret:RHE_CH03094.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q2K5M6.
OMA	Q2K5M6. PGKIITE.
Family and domain databases
HAMAP	MF_01518. [Tree]
InterPro	IPR006679. Adenine_deam. IPR006680. Amidohydro_1. [Graphical view]
Pfam	PF01979. Amidohydro_1. 1 hit. [Graphical view]
TIGRFAMs	TIGR01178. ade. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ADEC1_RHIEC

Accession

Primary (citable) accession number: Q2K5M6

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 26, 2007
Last sequence update:	March 7, 2006
Last modified:	June 16, 2009
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)