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Q2K5J8 (Q2K5J8_RHIEC) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glycerol kinase 1 HAMAP MF_00186
EC=2.7.1.30 HAMAP MF_00186
Alternative name(s):
ATP:glycerol 3-phosphotransferase 1 HAMAP MF_00186
Glycerokinase 1 HAMAP MF_00186
Gene names
Name:glpKch2 EMBL ABC91888.1
Synonyms:glpK1 HAMAP MF_00186
Ordered Locus Names:RHE_CH03122
OrganismRhizobium etli (strain CFN 42 / ATCC 51251) [Complete proteome] [HAMAP]
Taxonomic identifier347834 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Rhizobium

Protein attributes

Sequence length497 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Key enzyme in the regulation of glycerol uptake and metabolism By similarity. HAMAP MF_00186 SAAS SAAS018483

Catalytic activity

ATP + glycerol = ADP + sn-glycerol 3-phosphate. HAMAP MF_00186 SAAS SAAS018483

Pathway

Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1. HAMAP MF_00186 SAAS SAAS018483

Sequence similarities

Belongs to the FGGY kinase family. HAMAP MF_00186 RuleBase RU003733

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding411 – 4155ATP By similarity HAMAP MF_00186

Sites

Binding site121Substrate By similarity HAMAP MF_00186
Binding site161ATP By similarity HAMAP MF_00186
Binding site821Substrate By similarity HAMAP MF_00186
Binding site1341Substrate By similarity HAMAP MF_00186
Binding site2431Substrate By similarity HAMAP MF_00186
Binding site2651ATP By similarity HAMAP MF_00186
Binding site3081ATP; via carbonyl oxygen By similarity HAMAP MF_00186

Sequences

Sequence LengthMass (Da)Tools
Q2K5J8 [UniParc].

Last modified March 7, 2006. Version 1.
Checksum: 10F0202D0DA6E8EB

FASTA49754,406
        10         20         30         40         50         60 
MSGYVLAIDQ GTTSTRAIVF DGDMHVAGKG QKEFTQIYPR SGWVEHDPEE IWDSVVSTVQ 

        70         80         90        100        110        120 
MAPRDAEVAA KDIAALGITN QRETVVVWER ETGRPIQNAI VWQDRRTASY CDNLKRQDLE 

       130        140        150        160        170        180 
RLFTKKTGLI LDPYFSGTKL SWMLANVKGA RTRAARGDLC FGTIDTFLIW RLTGGKSFVT 

       190        200        210        220        230        240 
DATNASRTLM YNIAENAWDE DLLDILRVPA AMLPEVRDCA ADFGTVDPEI FGAAIPILGV 

       250        260        270        280        290        300 
AGDQQAATIG QACFAPGMLK STYGTGCFAL LNTGADMVRS KNRLLTTIAY RLDGETTYAL 

       310        320        330        340        350        360 
EGSIFIAGAA VQWLRDGVGI IGSAAETNAL AERADPTQEV YLVPAFTGLG APHWDAKARG 

       370        380        390        400        410        420 
AIFGLTRNTG PAELSRAALE AVCFQTRDLL DAMQKDWKNS GDDTVLRVDG GMVASDWTMQ 

       430        440        450        460        470        480 
RLADLLDAPV DRPMILETTA LGAAWLAGSR AGVWPDKEDF STTWKRDRRF EPDMDEKVRA 

       490 
AKLKGWRSAV RRTLSEG

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References

[1]"The partitioned Rhizobium etli genome: genetic and metabolic redundancy in seven interacting replicons."
Gonzalez V., Santamaria R.I., Bustos P., Hernandez-Gonzalez I., Medrano-Soto A., Moreno-Hagelsieb G., Janga S.C., Ramirez M.A., Jimenez-Jacinto V., Collado-Vides J., Davila G.
Proc. Natl. Acad. Sci. U.S.A. 103:3834-3839(2006) [PubMed: 16505379] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000133 Genomic DNA. Translation: ABC91888.1.
RefSeqYP_470615.1. NC_007761.1.

3D structure databases

ProteinModelPortalQ2K5J8.
SMRQ2K5J8. Positions 4-494.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ2K5J8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3893416.
GenomeReviewsGene locus RHE_CH03122 in contig CP000133_GR.
KEGGret:RHE_CH03122.
PATRIC23087885. VBIRhiEtl108884_3593.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0554.
HOGENOMHBG511469.
OMACYQTRDL.
PhylomeDBQ2K5J8.
ProtClustDBCLSK863056.

Family and domain databases

HAMAPMF_00186. Glycerol_kin.
[Tree]
InterProIPR000577. Carb_kinase_FGGY.
IPR018485. Carb_kinase_FGGY_C.
IPR018483. Carb_kinase_FGGY_CS.
IPR018484. Carb_kinase_FGGY_N.
IPR005999. Glycerol_kin.
[Graphical view]
KOK00864.
PANTHERPTHR10196. FGGY_kin. 1 hit.
PTHR10196:SF9. Glycerol_kin. 1 hit.
PfamPF02782. FGGY_C. 1 hit.
PF00370. FGGY_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR01311. Glycerol_kin. 1 hit.
PROSITEPS00445. FGGY_KINASES_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ2K5J8_RHIEC
AccessionPrimary (citable) accession number: Q2K5J8
Entry history
Integrated into UniProtKB/TrEMBL: March 7, 2006
Last sequence update: March 7, 2006
Last modified: December 14, 2011
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info