Q2K4Q9 (ADEC2_RHIEC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Adenine deaminase 2
Short name=Adenase 2
Short name=Adenine aminase 2
EC=3.5.4.2

Gene names

Name:	ade2
Synonyms:	adeC2
Ordered Locus Names:	RHE_CH03420

Organism

Rhizobium etli (strain CFN 42 / ATCC 51251) [Complete proteome] [HAMAP]

Taxonomic identifier

347834 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Rhizobium

Protein attributes

Sequence length	595 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Adenine + H2O = hypoxanthine + NH3. HAMAP MF_01518
Cofactor	Manganese By similarity. HAMAP MF_01518
Sequence similarities	Belongs to the adenine deaminase family.

Ontologies

Keywords
Ligand	Manganese
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	adenine catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	adenine deaminase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 595	595	Adenine deaminase 2 HAMAP MF_01518		PRO_0000292393

Sequences

	Sequence		Length	Mass (Da)
	Q2K4Q9 [UniParc]. Last modified March 7, 2006. Version 1. Checksum: E94689C9F6409813	FASTA	595	62,579
	10 20 30 40 50 60 MNAIARQEPF DLNDPALRAR AVAAARGDAP FDMLITGGRL LDAVTGLIRE ADIGLVGALI 70 80 90 100 110 120 ASVHAPASRT DAVEIIDATG GILTPGLIDM HMHVESSMVT PAEYASAVLP HGVTTVVWDP 130 140 150 160 170 180 HEFGNVQGLD GVRWAIEAAR TLPLRMILLA PSCVPSAPGL ELAGADFDAA VIAEMLRSPA 190 200 210 220 230 240 VGGVAEVMNM RGVIDGDPRM SAIVNSGLAS GKLVCGHARG LTGADLNAFM AAGVTSDHEL 250 260 270 280 290 300 TSGADLAAKL SAGLTIELRG SHDHLLQEFV EVLNGLGHLP ATVTLCTDDV FPDELYQSGG 310 320 330 340 350 360 LDEVARRLVR YGMKPEWALR AATFNAAQRL KRSDLGLVAS GRRADLVLFE DLTELRARLV 370 380 390 400 410 420 ISDGRIVARN GSMEAAVQPL DTAPLINSTK LPPLTESDFR VPAKGARVRI ATIDRPRFTQ 430 440 450 460 470 480 WGEAETEIRD GFVVPPAGSA MIAVAHRHGK AGGTPRIGFL TGWGEWRGAF CTTVSHDSHN 490 500 510 520 530 540 LTVFGGDARD MALAANAVIK AGGGLAVAKD GAIQAILPLP LSGLVTDASL KDTASAFSDI 550 560 570 580 590 RKAMDKIVDW KPPYRVFKAC FGATLACNAG PHQTDRGIAD VTTGKVLESP VLEIF

References

[1]

"The partitioned Rhizobium etli genome: genetic and metabolic redundancy in seven interacting replicons." Gonzalez V., Santamaria R.I., Bustos P., Hernandez-Gonzalez I., Medrano-Soto A., Moreno-Hagelsieb G., Janga S.C., Ramirez M.A., Jimenez-Jacinto V., Collado-Vides J., Davila G. Proc. Natl. Acad. Sci. U.S.A. 103:3834-3839(2006) [PubMed: 16505379] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CFN 42 / ATCC 51251.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000133 Genomic DNA. Translation: ABC92177.1.
RefSeq	YP_470904.1. NC_007761.1.
3D structure databases
ProteinModelPortal	Q2K4Q9.
ModBase	Search...
Protein-protein interaction databases
STRING	Q2K4Q9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3893504.
GenomeReviews	Gene locus RHE_CH03420 in contig CP000133_GR.
KEGG	ret:RHE_CH03420.
PATRIC	23088507. VBIRhiEtl108884_3897.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1001.
HOGENOM	HBG725357.
OMA	IELRGSH.
PhylomeDB	Q2K4Q9.
ProtClustDB	CLSK881699.
Family and domain databases
HAMAP	MF_01518. Adenine_deamin. [Tree]
InterPro	IPR006679. Adenine_deam. IPR006680. Amidohydro_1. IPR011059. Metal-dep_hydrolase_composite. [Graphical view]
KO	K01486.
Pfam	PF01979. Amidohydro_1. 1 hit. [Graphical view]
SUPFAM	SSF51338. Metalo_hydrolase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ADEC2_RHIEC

Accession

Primary (citable) accession number: Q2K4Q9

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 26, 2007
Last sequence update:	March 7, 2006
Last modified:	January 25, 2012
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program