ID   Q2K475_RHIEC            Unreviewed;       489 AA.
AC   Q2K475;
DT   07-MAR-2006, integrated into UniProtKB/TrEMBL.
DT   07-MAR-2006, sequence version 1.
DT   27-MAR-2024, entry version 96.
DE   SubName: Full=Adenylate cyclase protein {ECO:0000313|EMBL:ABC92361.1};
GN   OrderedLocusNames=RHE_CH03606 {ECO:0000313|EMBL:ABC92361.1};
OS   Rhizobium etli (strain CFN 42 / ATCC 51251).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX   NCBI_TaxID=347834 {ECO:0000313|EMBL:ABC92361.1, ECO:0000313|Proteomes:UP000001936};
RN   [1] {ECO:0000313|EMBL:ABC92361.1, ECO:0000313|Proteomes:UP000001936}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CFN 42 / ATCC 51251 {ECO:0000313|Proteomes:UP000001936};
RX   PubMed=16505379; DOI=10.1073/pnas.0508502103;
RA   Gonzalez V., Santamaria R.I., Bustos P., Hernandez-Gonzalez I.,
RA   Medrano-Soto A., Moreno-Hagelsieb G., Janga S.C., Ramirez M.A.,
RA   Jimenez-Jacinto V., Collado-Vides J., Davila G.;
RT   "The partitioned Rhizobium etli genome: genetic and metabolic redundancy in
RT   seven interacting replicons.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:3834-3839(2006).
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DR   EMBL; CP000133; ABC92361.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q2K475; -.
DR   KEGG; ret:RHE_CH03606; -.
DR   eggNOG; COG2114; Bacteria.
DR   HOGENOM; CLU_523442_0_0_5; -.
DR   Proteomes; UP000001936; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR021796; Tll0287-like.
DR   PANTHER; PTHR43081:SF16; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC; 1.
DR   PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR   Pfam; PF11845; DUF3365; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001936};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        165..186
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          244..379
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
SQ   SEQUENCE   489 AA;  54018 MW;  B1F968D988283AA5 CRC64;
     MSSLISSIRS YYSANIVGRV LAAHASGATA GTVVSHNYAN IPGAIPLPAT LSLELGDVIK
     EQQANITYRF VSDLPFKSRA SHELDDFEKR ALGALRANPQ QTLSDLTRVG LTDTLRFITP
     VVMGQACVAC HNTHPESPKT DWKVGDVRGI QEVIIKQPYA SNVFAFKYLL CYFLFVAVIG
     LSFILLQRQQ ARAIHGANRD LEAANEFLAS VSLKISRYLS PQIYKSIFSG QKDVVVHTER
     KRLTIFFSDI KDFTATTERL QPEALTEMLN EYLTEMSNIA LTHGGTVDKF IGDAMLVFFG
     DPETKGPEED AKACLRMAVD MQRRLGELKD RWRRNGTEEP FVVRMGINSG YCNVGNFGSN
     DRMDYTIIGA EANLAARLQS IAQGGEIVIS YETYALVNEI VDAHPLPPIT MKGIQREVVP
     YAVDGLTLGA DHKSRVLSEH LSGLDLHLDM SRLEPADRLR VRTALKEAIA ALDDALPEAA
     RLRQDAGQM
//