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Protein

Xylose isomerase

Gene

xylA

Organism
Rhizobium etli (strain CFN 42 / ATCC 51251)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei100UniRule annotation1
Active sitei103UniRule annotation1
Metal bindingi231Magnesium 1UniRule annotation1
Metal bindingi267Magnesium 1UniRule annotation1
Metal bindingi267Magnesium 2UniRule annotation1
Metal bindingi270Magnesium 2UniRule annotation1
Metal bindingi295Magnesium 1UniRule annotation1
Metal bindingi306Magnesium 2UniRule annotation1
Metal bindingi308Magnesium 2UniRule annotation1
Metal bindingi338Magnesium 1UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processCarbohydrate metabolism, Xylose metabolism
LigandMagnesium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:RHE_CH03648
OrganismiRhizobium etli (strain CFN 42 / ATCC 51251)
Taxonomic identifieri347834 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium
Proteomesi
  • UP000001936 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000264501 – 436Xylose isomeraseAdd BLAST436

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi347834.RHE_CH03648

Structurei

3D structure databases

ProteinModelPortaliQ2K433
SMRiQ2K433
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C93 Bacteria
COG2115 LUCA
KOiK01805
OMAiHTFQHEL

Family and domain databases

HAMAPiMF_00455 Xylose_isom_A, 1 hit
InterProiView protein in InterPro
IPR036237 Xyl_isomerase-like_sf
IPR013452 Xylose_isom_bac
IPR001998 Xylose_isomerase
PANTHERiPTHR32176:SF0 PTHR32176:SF0, 1 hit
PRINTSiPR00688 XYLOSISMRASE
SUPFAMiSSF51658 SSF51658, 1 hit
TIGRFAMsiTIGR02630 xylose_isom_A, 1 hit
PROSITEiView protein in PROSITE
PS51415 XYLOSE_ISOMERASE, 1 hit

Sequencei

Sequence statusi: Complete.

Q2K433-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTGFFGDIQ KIKYEGPDST NPLAFRYYQP DEIVLGKRME DHLRFAVAYW
60 70 80 90 100
HTFTWPGGDP FGGQTFLRPW FEDTMKAAKL KADVAFEFFS LLGAPYYCFH
110 120 130 140 150
DADVRPEGKN FAENTKNLNE IVDYFAEKQA ATGTKLLWGT ANLFSNRRYM
160 170 180 190 200
SGAATNPDPD VFAFAAATVK TCIDATQKLG GENYVLWGGR EGYETLLNTD
210 220 230 240 250
LKRELDQLGR FLNLVVEYKH KIGFKGTILI EPKPQEPTKH QYDYDVATVY
260 270 280 290 300
GFLKKHGLEN EVKVNIEQGH AILAGHSFEH ELALANALGI FGSIDMNRND
310 320 330 340 350
YQSGWDTDQF PNNVPEMALA YYHVLAGGGF KTGGTNFDSK LRRQSLDPAD
360 370 380 390 400
LLIGHIGGMD CCARGLKAAA KMIEDKALSQ PLADRYAGWE SVEAQKLFRG
410 420 430
EYSLDEIANW VESKDVNPQP KSGKQELLEN VVNRYV
Length:436
Mass (Da):48,973
Last modified:March 7, 2006 - v1
Checksum:i588569750004D207
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000133 Genomic DNA Translation: ABC92403.1
RefSeqiWP_011426861.1, NC_007761.1

Genome annotation databases

EnsemblBacteriaiABC92403; ABC92403; RHE_CH03648
GeneIDi24297892
KEGGiret:RHE_CH03648

Similar proteinsi

Entry informationi

Entry nameiXYLA_RHIEC
AccessioniPrimary (citable) accession number: Q2K433
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: March 7, 2006
Last modified: April 25, 2018
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health