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Protein

Xylose isomerase

Gene

xylA

Organism
Rhizobium etli (strain CFN 42 / ATCC 51251)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei100UniRule annotation1
Active sitei103UniRule annotation1
Metal bindingi231Magnesium 1UniRule annotation1
Metal bindingi267Magnesium 1UniRule annotation1
Metal bindingi267Magnesium 2UniRule annotation1
Metal bindingi270Magnesium 2UniRule annotation1
Metal bindingi295Magnesium 1UniRule annotation1
Metal bindingi306Magnesium 2UniRule annotation1
Metal bindingi308Magnesium 2UniRule annotation1
Metal bindingi338Magnesium 1UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Carbohydrate metabolism, Pentose shunt, Xylose metabolism

Keywords - Ligandi

Magnesium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:RHE_CH03648
OrganismiRhizobium etli (strain CFN 42 / ATCC 51251)
Taxonomic identifieri347834 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium
Proteomesi
  • UP000001936 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000264501 – 436Xylose isomeraseAdd BLAST436

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi347834.RHE_CH03648.

Structurei

3D structure databases

ProteinModelPortaliQ2K433.
SMRiQ2K433.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C93. Bacteria.
COG2115. LUCA.
KOiK01805.
OMAiHTFQHEL.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A. 1 hit.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2K433-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTGFFGDIQ KIKYEGPDST NPLAFRYYQP DEIVLGKRME DHLRFAVAYW
60 70 80 90 100
HTFTWPGGDP FGGQTFLRPW FEDTMKAAKL KADVAFEFFS LLGAPYYCFH
110 120 130 140 150
DADVRPEGKN FAENTKNLNE IVDYFAEKQA ATGTKLLWGT ANLFSNRRYM
160 170 180 190 200
SGAATNPDPD VFAFAAATVK TCIDATQKLG GENYVLWGGR EGYETLLNTD
210 220 230 240 250
LKRELDQLGR FLNLVVEYKH KIGFKGTILI EPKPQEPTKH QYDYDVATVY
260 270 280 290 300
GFLKKHGLEN EVKVNIEQGH AILAGHSFEH ELALANALGI FGSIDMNRND
310 320 330 340 350
YQSGWDTDQF PNNVPEMALA YYHVLAGGGF KTGGTNFDSK LRRQSLDPAD
360 370 380 390 400
LLIGHIGGMD CCARGLKAAA KMIEDKALSQ PLADRYAGWE SVEAQKLFRG
410 420 430
EYSLDEIANW VESKDVNPQP KSGKQELLEN VVNRYV
Length:436
Mass (Da):48,973
Last modified:March 7, 2006 - v1
Checksum:i588569750004D207
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000133 Genomic DNA. Translation: ABC92403.1.
RefSeqiWP_011426861.1. NC_007761.1.

Genome annotation databases

EnsemblBacteriaiABC92403; ABC92403; RHE_CH03648.
GeneIDi24297892.
KEGGiret:RHE_CH03648.
PATRICi23088995. VBIRhiEtl108884_4139.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000133 Genomic DNA. Translation: ABC92403.1.
RefSeqiWP_011426861.1. NC_007761.1.

3D structure databases

ProteinModelPortaliQ2K433.
SMRiQ2K433.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi347834.RHE_CH03648.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABC92403; ABC92403; RHE_CH03648.
GeneIDi24297892.
KEGGiret:RHE_CH03648.
PATRICi23088995. VBIRhiEtl108884_4139.

Phylogenomic databases

eggNOGiENOG4105C93. Bacteria.
COG2115. LUCA.
KOiK01805.
OMAiHTFQHEL.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A. 1 hit.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiXYLA_RHIEC
AccessioniPrimary (citable) accession number: Q2K433
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: March 7, 2006
Last modified: November 2, 2016
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.