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Q2K433 (XYLA_RHIEC) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Xylose isomerase

EC=5.3.1.5
Gene names
Name:xylA
Ordered Locus Names:RHE_CH03648
OrganismRhizobium etli (strain CFN 42 / ATCC 51251) [Complete proteome] [HAMAP]
Taxonomic identifier347834 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium

Protein attributes

Sequence length436 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-xylopyranose = D-xylulose. HAMAP-Rule MF_00455

Cofactor

Binds 2 magnesium ions per subunit By similarity. HAMAP-Rule MF_00455

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00455

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00455.

Sequence similarities

Belongs to the xylose isomerase family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Pentose shunt
Xylose metabolism
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processD-xylose metabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

pentose-phosphate shunt

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionmagnesium ion binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

xylose isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 436436Xylose isomerase HAMAP-Rule MF_00455
PRO_1000026450

Sites

Active site1001 By similarity
Active site1031 By similarity
Metal binding2311Magnesium 1 By similarity
Metal binding2671Magnesium 1 By similarity
Metal binding2671Magnesium 2 By similarity
Metal binding2701Magnesium 2 By similarity
Metal binding2951Magnesium 1 By similarity
Metal binding3061Magnesium 2 By similarity
Metal binding3081Magnesium 2 By similarity
Metal binding3381Magnesium 1 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q2K433 [UniParc].

Last modified March 7, 2006. Version 1.
Checksum: 588569750004D207

FASTA43648,973
        10         20         30         40         50         60 
MSTGFFGDIQ KIKYEGPDST NPLAFRYYQP DEIVLGKRME DHLRFAVAYW HTFTWPGGDP 

        70         80         90        100        110        120 
FGGQTFLRPW FEDTMKAAKL KADVAFEFFS LLGAPYYCFH DADVRPEGKN FAENTKNLNE 

       130        140        150        160        170        180 
IVDYFAEKQA ATGTKLLWGT ANLFSNRRYM SGAATNPDPD VFAFAAATVK TCIDATQKLG 

       190        200        210        220        230        240 
GENYVLWGGR EGYETLLNTD LKRELDQLGR FLNLVVEYKH KIGFKGTILI EPKPQEPTKH 

       250        260        270        280        290        300 
QYDYDVATVY GFLKKHGLEN EVKVNIEQGH AILAGHSFEH ELALANALGI FGSIDMNRND 

       310        320        330        340        350        360 
YQSGWDTDQF PNNVPEMALA YYHVLAGGGF KTGGTNFDSK LRRQSLDPAD LLIGHIGGMD 

       370        380        390        400        410        420 
CCARGLKAAA KMIEDKALSQ PLADRYAGWE SVEAQKLFRG EYSLDEIANW VESKDVNPQP 

       430 
KSGKQELLEN VVNRYV 

« Hide

References

[1]"The partitioned Rhizobium etli genome: genetic and metabolic redundancy in seven interacting replicons."
Gonzalez V., Santamaria R.I., Bustos P., Hernandez-Gonzalez I., Medrano-Soto A., Moreno-Hagelsieb G., Janga S.C., Ramirez M.A., Jimenez-Jacinto V., Collado-Vides J., Davila G.
Proc. Natl. Acad. Sci. U.S.A. 103:3834-3839(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CFN 42 / ATCC 51251.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000133 Genomic DNA. Translation: ABC92403.1.
RefSeqYP_471130.1. NC_007761.1.

3D structure databases

ProteinModelPortalQ2K433.
SMRQ2K433. Positions 4-436.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING347834.RHE_CH03648.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABC92403; ABC92403; RHE_CH03648.
GeneID3891887.
KEGGret:RHE_CH03648.
PATRIC23088995. VBIRhiEtl108884_4139.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2115.
KOK01805.
OMAKADSAFE.
OrthoDBEOG62NX4R.

Enzyme and pathway databases

BioCycRETL347834:GJJ0-3665-MONOMER.

Family and domain databases

Gene3D3.20.20.150. 1 hit.
HAMAPMF_00455. Xylose_isom_A.
InterProIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSPR00688. XYLOSISMRASE.
SUPFAMSSF51658. SSF51658. 1 hit.
TIGRFAMsTIGR02630. xylose_isom_A. 1 hit.
PROSITEPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameXYLA_RHIEC
AccessionPrimary (citable) accession number: Q2K433
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: March 7, 2006
Last modified: May 14, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families