Q2K237 (Q2K237_RHIEC) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrA 1 HAMAP MF_01401
Short name=Protein-methionine-S-oxide reductase 1 HAMAP MF_01401
EC=1.8.4.11 HAMAP MF_01401

Alternative name(s):
Peptide-methionine (S)-S-oxide reductase 1 HAMAP MF_01401

Gene names

Name:	msrAb EMBL ABC93152.1
Synonyms:	msrA1 HAMAP MF_01401
Ordered Locus Names:	RHE_PB00110

Encoded on

Plasmid p42b EMBL ABC93152.1

Organism

Rhizobium etli (strain CFN 42 / ATCC 51251) [Complete proteome] [HAMAP]

Taxonomic identifier

347834 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Rhizobium

Protein attributes

Sequence length	169 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP MF_01401
Catalytic activity	L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569 Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569
Sequence similarities	Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401

Ontologies

Keywords
Molecular function	Oxidoreductase HAMAP MF_01401 SAAS SAAS002569 EMBL ABC93152.1
Technical term	Complete proteome Plasmid EMBL ABC93152.1
Gene Ontology (GO)
Biological process	protein modification process Inferred from electronic annotation. Source: HAMAP
Molecular function	peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	12	1	By similarity HAMAP MF_01401

Sequences

	Sequence		Length	Mass (Da)
	Q2K237 [UniParc]. Last modified March 7, 2006. Version 1. Checksum: 4319422E8EBEE8E4	FASTA	169	19,120
	10 20 30 40 50 60 MTEERAVLAG GCFWGMQDLI RRLNGVISTR VGYTGGDVPN ATYRNHGTHA EAIEIIFDPA 70 80 90 100 110 120 KTSYRDILEF FFQIHDPTTR NRQGNDVGMS YRSAIFYTSP EQERVARDTI ADVDASGLWP 130 140 150 160 GKVVTEVVPA GDFWEAEPEH QDYLERIPNG YTCHFVRPGW KLPARQKIA

References

[1]

"The partitioned Rhizobium etli genome: genetic and metabolic redundancy in seven interacting replicons." Gonzalez V., Santamaria R.I., Bustos P., Hernandez-Gonzalez I., Medrano-Soto A., Moreno-Hagelsieb G., Janga S.C., Ramirez M.A., Jimenez-Jacinto V., Collado-Vides J., Davila G. Proc. Natl. Acad. Sci. U.S.A. 103:3834-3839(2006) [PubMed: 16505379] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000135 Genomic DNA. Translation: ABC93152.1.
RefSeq	YP_471879.1. NC_007763.1.
3D structure databases
ProteinModelPortal	Q2K237.
SMR	Q2K237. Positions 2-165.
ModBase	Search...
Protein-protein interaction databases
STRING	Q2K237.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3895100.
GenomeReviews	Gene locus RHE_PB00110 in contig CP000135_GR.
KEGG	ret:RHE_PB00110.
PATRIC	23090624. VBIRhiEtl108884_4943.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0225.
HOGENOM	HBG748152.
OMA	LNAYCAG.
PhylomeDB	Q2K237.
ProtClustDB	PRK14054.
Family and domain databases
HAMAP	MF_01401. MsrA. [Tree]
InterPro	IPR002569. Peptide_Met_Sox_Rdtase_MsrA. [Graphical view]
Gene3D	G3DSA:3.30.1060.10. MsrA. 1 hit.
KO	K07304.
Pfam	PF01625. PMSR. 1 hit. [Graphical view]
SUPFAM	SSF55068. MsrA. 1 hit.
TIGRFAMs	TIGR00401. MsrA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q2K237_RHIEC

Accession

Primary (citable) accession number: Q2K237

Entry history

Integrated into UniProtKB/TrEMBL:	March 7, 2006
Last sequence update:	March 7, 2006
Last modified:	December 14, 2011
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)