Q2K0S7 (RBSA3_RHIEC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribose import ATP-binding protein RbsA 3
EC=3.6.3.17

Gene names

Name:	rbsA3
Ordered Locus Names:	RHE_PE00288

Encoded on

Plasmid p42e

Organism

Rhizobium etli (strain CFN 42 / ATCC 51251) [Complete proteome] [HAMAP]

Taxonomic identifier

347834 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Rhizobium › Rhizobium etli

Protein attributes

Sequence length	511 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of the ABC transporter complex RbsABCD involved in ribose import. Responsible for energy coupling to the transport system By similarity.
Catalytic activity	ATP + H2O + monosaccharide(Out) = ADP + phosphate + monosaccharide(In).
Subunit structure	The complex is composed of two ATP-binding proteins (RbsA), two transmembrane proteins (RbsC and RbsD) and a solute-binding protein (RbsB) Potential.
Subcellular location	Cell inner membrane; Peripheral membrane protein By similarity.
Sequence similarities	Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. [View classification] Contains 2 ABC transporter domains.

Ontologies

Keywords
Biological process	Sugar transport Transport
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Repeat
Ligand	ATP-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome Plasmid
Gene Ontology (GO)
Biological_process	ATP catabolic process Inferred from electronic annotation. Source: GOC
Cellular_component	plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW monosaccharide-transporting ATPase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 511	511	Ribose import ATP-binding protein RbsA 3		PRO_0000261082
Regions
	Domain	21 – 257	237	ABC transporter 1
	Domain	256 – 511	256	ABC transporter 2
	Nucleotide binding	53 – 60	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	Q2K0S7 [UniParc]. Last modified March 7, 2006. Version 1. Checksum: B732D4031EA34674	FASTA	511	55,448
	10 20 30 40 50 60 MNAAFQQPVT DSKTGDAPAI LEMRGISQIF PGVKALDNVS IALHPGTVTA LIGENGAGKS 70 80 90 100 110 120 TLVKILTGIY RPNEGEILVD GQPTSFASAQ AAIDAGVTAI HQETVLFDEL TVAENIFLGH 130 140 150 160 170 180 APRTRLRTID WQTMNSRSKT LLTALESNID PTIRLKDLSI AQRHLVAIAR ALSIEARIVI 190 200 210 220 230 240 MDEPTAALSR KEIDDLFRIV RGLKDQGKAI LFISHKFDEL YEIADDFVVF RDGRAVGQGR 250 260 270 280 290 300 LKETPQDEIV RMMVGRDVEN VFPKIDVAIG GPVLEVEKYC HRTEFRDVSL TLRRGEILGI 310 320 330 340 350 360 YGLIGAGRSE LAQSLFGVTK PLSGRLTLEG REISINSPHD AIKAGIVYVP EERGRHGLAL 370 380 390 400 410 420 PMPIYQNMTL PSLARTSRKG FLKAAEEFAL ARKYAERLDL RAAALSVPVG TLSGGNQQKV 430 440 450 460 470 480 VIGKWLATMP KVIILDEPTK GIDIGSKAAV HGFISELAAE GLSIIMISSE LPEIIGMSDR 490 500 510 VLVMKEGLSV GLFERDQLSP EALVRAATGN A

References

[1]

"The partitioned Rhizobium etli genome: genetic and metabolic redundancy in seven interacting replicons." Gonzalez V., Santamaria R.I., Bustos P., Hernandez-Gonzalez I., Medrano-Soto A., Moreno-Hagelsieb G., Janga S.C., Ramirez M.A., Jimenez-Jacinto V., Collado-Vides J., Davila G. Proc. Natl. Acad. Sci. U.S.A. 103:3834-3839(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CFN 42 / ATCC 51251.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000137 Genomic DNA. Translation: ABC93723.1.
RefSeq	YP_472450.1. NC_007765.1.
3D structure databases
ProteinModelPortal	Q2K0S7.
ModBase	Search...
Protein-protein interaction databases
STRING	347834.RHE_PE00288.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABC93723; ABC93723; RHE_PE00288.
GeneID	3895757.
KEGG	ret:RHE_PE00288.
PATRIC	23091846. VBIRhiEtl108884_5552.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1129.
KO	K10562.
OMA	ESNIDPT.
ProtClustDB	CLSK864371.
Enzyme and pathway databases
BioCyc	RETL347834:GJJ0-5005-MONOMER.
Family and domain databases
InterPro	IPR003593. AAA+_ATPase. IPR003439. ABC_transporter-like. IPR017871. ABC_transporter_CS. IPR015861. ABC_transpr_RbsA. [Graphical view]
Pfam	PF00005. ABC_tran. 2 hits. [Graphical view]
SMART	SM00382. AAA. 2 hits. [Graphical view]
PROSITE	PS00211. ABC_TRANSPORTER_1. 1 hit. PS50893. ABC_TRANSPORTER_2. 2 hits. PS51254. RBSA. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RBSA3_RHIEC

Accession

Primary (citable) accession number: Q2K0S7

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 28, 2006
Last sequence update:	March 7, 2006
Last modified:	May 1, 2013
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program