ID   TPIS2_RHIEC             Reviewed;         267 AA.
AC   Q2JZQ2;
DT   16-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   07-MAR-2006, sequence version 1.
DT   16-JUN-2009, entry version 24.
DE   RecName: Full=Triosephosphate isomerase 2;
DE            Short=TIM 2;
DE            EC=5.3.1.1;
DE   AltName: Full=Triose-phosphate isomerase 2;
GN   Name=tpiA2; Synonyms=tpiAf; OrderedLocusNames=RHE_PF00040;
OS   Rhizobium etli (strain CFN 42 / ATCC 51251).
OG   Plasmid p42f.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX   NCBI_TaxID=347834;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16505379; DOI=10.1073/pnas.0508502103;
RA   Gonzalez V., Santamaria R.I., Bustos P., Hernandez-Gonzalez I.,
RA   Medrano-Soto A., Moreno-Hagelsieb G., Janga S.C., Ramirez M.A.,
RA   Jimenez-Jacinto V., Collado-Vides J., Davila G.;
RT   "The partitioned Rhizobium etli genome: genetic and metabolic
RT   redundancy in seven interacting replicons.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:3834-3839(2006).
CC   -!- CATALYTIC ACTIVITY: D-glyceraldehyde 3-phosphate = glycerone
CC       phosphate.
CC   -!- PATHWAY: Carbohydrate biosynthesis; gluconeogenesis.
CC   -!- PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-
CC       phosphate from glycerone phosphate: step 1/1.
CC   -!- SUBUNIT: Homodimer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (Probable).
CC   -!- SIMILARITY: Belongs to the triosephosphate isomerase family.
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DR   EMBL; CP000138; ABC93934.1; -; Genomic_DNA.
DR   RefSeq; YP_472661.1; -.
DR   GeneID; 3896224; -.
DR   GenomeReviews; CP000138_GR; RHE_PF00040.
DR   KEGG; ret:RHE_PF00040; -.
DR   HOGENOM; Q2JZQ2; -.
DR   OMA; Q2JZQ2; EHFGETD.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004807; F:triose-phosphate isomerase activity; IEA:HAMAP.
DR   GO; GO:0006094; P:gluconeogenesis; IEA:HAMAP.
DR   GO; GO:0006096; P:glycolysis; IEA:HAMAP.
DR   GO; GO:0006098; P:pentose-phosphate shunt; IEA:HAMAP.
DR   HAMAP; MF_00147; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR000652; Triosephosphate_isomerase.
DR   Gene3D; G3DSA:3.20.20.70; Aldolase_TIM; 1.
DR   PANTHER; PTHR21139; Triophos_ismrse; 1.
DR   Pfam; PF00121; TIM; 1.
DR   ProDom; PD001005; Triophos_ismrse; 1.
DR   TIGRFAMs; TIGR00419; tim; 1.
DR   PROSITE; PS00171; TIM_1; 1.
DR   PROSITE; PS51440; TIM_2; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Gluconeogenesis; Glycolysis; Isomerase;
KW   Pentose shunt; Plasmid.
FT   CHAIN         1    267       Triosephosphate isomerase 2.
FT                                /FTId=PRO_0000236166.
FT   ACT_SITE     95     95       Electrophile (By similarity).
FT   ACT_SITE    168    168       Proton acceptor (By similarity).
FT   BINDING      10     10       Substrate (By similarity).
SQ   SEQUENCE   267 AA;  29175 MW;  3A6085823E800D93 CRC64;
     MVVWVGTSFK MNKTLEEALA FARRLADADL ERDPRVQRFV IPSFTAVREV KRVLTESSVK
     VGAQNMHWED AGAWTGEISP LMLKDCRLDL VELGHSERRE HFGETDETVG LKAAAAIRHG
     LTPLICIGET LQERNEGRAD AVLRRQVEAA LRGVDTEAGE APILLAYEPV WAIGVNGIPA
     TADYASERHR GIAEVAKSIL GRPVPVLYGG SVNPGNCEEL IGQPDIDGLF IGRSAWSVEG
     YLDILARVSA AIDRSSPRQT ASERKLP
//