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Q2JXK8 (Q2JXK8_SYNJA) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Inorganic pyrophosphatase HAMAP MF_00209
EC=3.6.1.1 HAMAP MF_00209
Alternative name(s):
Pyrophosphate phospho-hydrolase HAMAP MF_00209
Gene names
Name:ppa HAMAP MF_00209
Ordered Locus Names:CYA_0251
OrganismSynechococcus sp. (strain JA-3-3Ab) (Cyanobacteria bacterium Yellowstone A-Prime) [Complete proteome] [HAMAP]
Taxonomic identifier321327 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Chroococcales › Synechococcus

Protein attributes

Sequence length173 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Diphosphate + H2O = 2 phosphate. HAMAP MF_00209

Cofactor

Binds 4 magnesium ions per subunit. Other metal ions can support activity, but at a lower rate. Two magnesium ions are required for the activation of the enzyme and are present before substrate binds, two additional magnesium ions form complexes with substrate and product By similarity. HAMAP MF_00209

Subcellular location

Cytoplasm By similarity HAMAP MF_00209.

Sequence similarities

Belongs to the PPase family. HAMAP MF_00209

Ontologies

Keywords
   Cellular componentCytoplasm HAMAP MF_00209
   LigandMagnesium HAMAP MF_00209
Metal-binding HAMAP MF_00209
   Molecular functionHydrolase HAMAP MF_00209 EMBL ABC98474.1
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processphosphate-containing compound metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functioninorganic diphosphatase activity

Inferred from electronic annotation. Source: HAMAP

magnesium ion binding

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding651Magnesium 1 By similarity HAMAP MF_00209
Metal binding701Magnesium 1 By similarity HAMAP MF_00209
Metal binding701Magnesium 2 By similarity HAMAP MF_00209
Metal binding1021Magnesium 1 By similarity HAMAP MF_00209

Sequences

Sequence LengthMass (Da)Tools
Q2JXK8 [UniParc].

Last modified March 7, 2006. Version 1.
Checksum: 3D87C32B8531E990

FASTA17319,181
        10         20         30         40         50         60 
MIDLSRIPAQ PKPGLLNLLI EIPGGSKNKY EFDKDMGVMA LDRVLYSSVQ YPYDYGFVPN 

        70         80         90        100        110        120 
TLAGDGDPLD GLVIMDQPTF PGCVIAVRPL GMLQMIDAGE PDEKLLCVPA KDPRYASVTR 

       130        140        150        160        170 
LEDIAQHRLD EIAEFFATYK RLEKKETQIL GWKGLAETEA VIASSIATYQ QSK

« Hide

References

[1]"Population level functional diversity in a microbial community revealed by comparative genomic and metagenomic analyses."
Bhaya D., Grossman A.R., Steunou A.-S., Khuri N., Cohan F.M., Hamamura N., Melendrez M.C., Bateson M.M., Ward D.M., Heidelberg J.F.
ISME J. 1:703-713(2007) [PubMed: 18059494] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: JA-3-3Ab.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000239 Genomic DNA. Translation: ABC98474.1.
RefSeqYP_473737.1. NC_007775.1.

3D structure databases

ProteinModelPortalQ2JXK8.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ2JXK8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3897628.
GenomeReviewsGene locus CYA_0251 in contig CP000239_GR.
KEGGcya:CYA_0251.
PATRIC23808773. VBISynSp90045_0253.
TIGRCYA_0251.

Phylogenomic databases

eggNOGCOG0221.
HOGENOMHBG529150.
OMAPNDFNVI.
PhylomeDBQ2JXK8.
ProtClustDBCLSK895996.

Enzyme and pathway databases

BioCycSSP321327:CYA_0251-MONOMER.

Family and domain databases

HAMAPMF_00209. Inorganic_PPase.
[Tree]
InterProIPR008162. Pyrophosphatase.
[Graphical view]
Gene3DG3DSA:3.90.80.10. Pyrophosphatase. 1 hit.
KOK01507.
PANTHERPTHR10286. Pyrophosphatase. 1 hit.
PfamPF00719. Pyrophosphatase. 1 hit.
[Graphical view]
SUPFAMSSF50324. Pyrophosphatase. 1 hit.
PROSITEPS00387. PPASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ2JXK8_SYNJA
AccessionPrimary (citable) accession number: Q2JXK8
Entry history
Integrated into UniProtKB/TrEMBL: March 7, 2006
Last sequence update: March 7, 2006
Last modified: January 25, 2012
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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