Reviewed, UniProtKB/Swiss-Prot Q2JWJ9 (COMB_SYNJA)

Names and origin

Protein names

Recommended name:
    Probable 2-phosphosulfolactate phosphatase
    EC=3.1.3.71

Gene names

Name:	comB
Ordered Locus Names:	CYA_0651

Organism

Synechococcus sp. (strain JA-3-3Ab) (Cyanobacteria bacterium Yellowstone A-Prime) [Complete proteome] [HAMAP]

Taxonomic identifier

321327 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechococcus

Protein attributes

Sequence length	242 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	(2R)-2-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate. HAMAP MF_00490
Cofactor	Magnesium By similarity.
Sequence similarities	Belongs to the comB family.

Ontologies

Keywords
Ligand	Magnesium
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	coenzyme M biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	2-phosphosulfolactate phosphatase activity Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 242	242	Probable 2-phosphosulfolactate phosphatase HAMAP MF_00490		PRO_1000014469

Sequences

	Sequence		Length	Mass (Da)
	Q2JWJ9-1 [UniParc]. Last modified March 7, 2006. Version 1. Checksum: 234B7FD4973ABE1D	FASTA	242	25,943
	10 20 30 40 50 60 MQLFHFHTPE QVPPAGIPAC AVAIDVLRAT TTIAAALAAG AEAVEVFADL QSLQAASRSW 70 80 90 100 110 120 PASKRLLAGE RGGKTVTGFD LGNSPREYTP ERVRDQRIFM STTNGTRTLQ RLERIPVVIT 130 140 150 160 170 180 AALVNLGAVV EFLRRGAFAE VWLVGSGWEG AFALEDTACA GAVLHRLGCS WEQLGNDEAV 190 200 210 220 230 240 AALALYQTWQ DNLLGLLRRS SHGQRLLAIS PENDSDLAYC AKLDRLSVVP QQVQPGVLAL AG

References

[1]

"Population level functional diversity in a microbial community revealed by comparative genomic and metagenomic analyses." Bhaya D., Grossman A.R., Steunou A.-S., Khuri N., Cohan F.M., Hamamura N., Melendrez M.C., Bateson M.M., Ward D.M., Heidelberg J.F. ISME J. 1:703-713(2007) [PubMed: 18059494] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000239 Genomic DNA. Translation: ABC98864.1.
RefSeq	YP_474127.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3897287.
GenomeReviews	Gene locus CYA_0651 in contig CP000239_GR.
KEGG	cya:CYA_0651.
TIGR	CYA_0651.
Phylogenomic databases
HOGENOM	Q2JWJ9.
OMA	Q2JWJ9. ATTTIAW.
Family and domain databases
HAMAP	MF_00490. [Tree]
InterPro	IPR005238. 2-PSlactate_phosphatase. [Graphical view]
Gene3D	G3DSA:3.90.1560.10. 2-PSlactate_phosphatase. 1 hit.
Pfam	PF04029. 2-ph_phosp. 1 hit. [Graphical view]
TIGRFAMs	TIGR00298. 2-ph_phosphatase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

COMB_SYNJA

Accession

Primary (citable) accession number: Q2JWJ9

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	March 7, 2006
Last modified:	May 5, 2009
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)