Q2JVD1 (Q2JVD1_SYNJA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphoadenosine phosphosulfate reductase HAMAP MF_00063
EC=1.8.4.8 HAMAP MF_00063

Alternative name(s):
3'-phosphoadenylylsulfate reductase HAMAP MF_00063
PAPS reductase, thioredoxin dependent HAMAP MF_00063
PAPS sulfotransferase HAMAP MF_00063
PAdoPS reductase HAMAP MF_00063

Gene names

Name:	cysH HAMAP MF_00063
Ordered Locus Names:	CYA_1123

Organism

Synechococcus sp. (strain JA-3-3Ab) (Cyanobacteria bacterium Yellowstone A-Prime) [Complete proteome] [HAMAP]

Taxonomic identifier

321327 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechococcus

Protein attributes

Sequence length	248 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Reduction of activated sulfate into sulfite By similarity. HAMAP MF_00063 SAAS SAAS002500
Catalytic activity	Adenosine 3',5'-bisphosphate + sulfite + thioredoxin disulfide = 3'-phosphoadenylyl sulfate + thioredoxin. HAMAP MF_00063 SAAS SAAS002500
Pathway	Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 3/3. HAMAP MF_00063 SAAS SAAS002500
Subcellular location	Cytoplasm By similarity HAMAP MF_00063 SAAS SAAS002500.
Sequence similarities	Belongs to the PAPS reductase family. CysH subfamily. HAMAP MF_00063

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_00063 SAAS SAAS002500
Molecular function	Oxidoreductase HAMAP MF_00063 SAAS SAAS002500 EMBL ABC99312.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	phosphoadenylyl-sulfate reductase (thioredoxin) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q2JVD1 [UniParc]. Last modified March 7, 2006. Version 1. Checksum: 05494355D14D2AD7	FASTA	248	28,008
	10 20 30 40 50 60 MTATLSSSGH WELAAQALRE QYQPQVASLS ERFEPLSASD LLAWAVAEFG DGLVLACSFG 70 80 90 100 110 120 PEDLVLIDLL TAIRPQVRAF FLDTDFHFPE TLQLQQQVLA RYPHLQLEIF KPLLTPEEQA 130 140 150 160 170 180 AQYEPELYRT NPDLCCSLRK VEPLNRALAN CTTWITGMRR EQSPTRADIG KVQWDGKRNR 190 200 210 220 230 240 LKLNPLADWT NGQVWKYILD HGIPYNPLHD RNYPSIGCIH CTAPVEPGAD PRSGRWKGTA KTECGLHT

References

[1]

"Population level functional diversity in a microbial community revealed by comparative genomic and metagenomic analyses." Bhaya D., Grossman A.R., Steunou A.-S., Khuri N., Cohan F.M., Hamamura N., Melendrez M.C., Bateson M.M., Ward D.M., Heidelberg J.F. ISME J. 1:703-713(2007) [PubMed: 18059494] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: JA-3-3Ab.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000239 Genomic DNA. Translation: ABC99312.1.
RefSeq	YP_474575.1. NC_007775.1.
3D structure databases
ProteinModelPortal	Q2JVD1.
ModBase	Search...
Protein-protein interaction databases
STRING	Q2JVD1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3898397.
GenomeReviews	Gene locus CYA_1123 in contig CP000239_GR.
KEGG	cya:CYA_1123.
PATRIC	23810517. VBISynSp90045_1113.
TIGR	CYA_1123.
Phylogenomic databases
eggNOG	COG0175.
HOGENOM	HBG758022.
OMA	FEETLAY.
PhylomeDB	Q2JVD1.
ProtClustDB	CLSK423129.
Enzyme and pathway databases
BioCyc	SSP321327:CYA_1123-MONOMER.
Family and domain databases
HAMAP	MF_00063. CysH. [Tree]
InterPro	IPR004511. PAPS/APS_Rdtase. IPR002500. PAPS_reduct. IPR014729. Rossmann-like_a/b/a_fold. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
KO	K00390.
Pfam	PF01507. PAPS_reduct. 1 hit. [Graphical view]
PIRSF	PIRSF000857. PAPS_reductase. 1 hit.
TIGRFAMs	TIGR00434. CysH. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q2JVD1_SYNJA

Accession

Primary (citable) accession number: Q2JVD1

Entry history

Integrated into UniProtKB/TrEMBL:	March 7, 2006
Last sequence update:	March 7, 2006
Last modified:	January 25, 2012
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)