ID   Q2JUX2_SYNJA            Unreviewed;       293 AA.
AC   Q2JUX2;
DT   07-MAR-2006, integrated into UniProtKB/TrEMBL.
DT   07-MAR-2006, sequence version 1.
DT   03-NOV-2009, entry version 31.
DE   SubName: Full=Dihydrodipicolinate reductase;
DE            EC=1.3.1.26;
GN   Name=dapB; OrderedLocusNames=CYA_1305;
OS   Synechococcus sp. (strain JA-3-3Ab) (Cyanobacteria bacterium
OS   Yellowstone A-Prime).
OC   Bacteria; Cyanobacteria; Chroococcales; Synechococcus.
OX   NCBI_TaxID=321327;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=18059494; DOI=10.1038/ismej.2007.46;
RA   Bhaya D., Grossman A.R., Steunou A.-S., Khuri N., Cohan F.M.,
RA   Hamamura N., Melendrez M.C., Bateson M.M., Ward D.M., Heidelberg J.F.;
RT   "Population level functional diversity in a microbial community
RT   revealed by comparative genomic and metagenomic analyses.";
RL   ISME J. 1:703-713(2007).
CC   -!- CATALYTIC ACTIVITY: 2,3,4,5-tetrahydrodipicolinate + NAD(P)(+) =
CC       2,3-dihydrodipicolinate + NAD(P)H.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-lysine biosynthesis via DAP
CC       pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 4/4.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
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DR   EMBL; CP000239; ABC99485.1; -; Genomic_DNA.
DR   RefSeq; YP_474748.1; -.
DR   STRING; Q2JUX2; -.
DR   GeneID; 3899474; -.
DR   GenomeReviews; CP000239_GR; CYA_1305.
DR   KEGG; cya:CYA_1305; -.
DR   TIGR; CYA_1305; -.
DR   HOGENOM; Q2JUX2; -.
DR   OMA; TCIKTAE; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005488; F:binding; IEA:InterPro.
DR   GO; GO:0008839; F:dihydrodipicolinate reductase activity; IEA:EC.
DR   GO; GO:0019877; P:diaminopimelate biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   InterPro; IPR000846; DapB.
DR   InterPro; IPR011770; Dihydrodipicolinate_Rdtase.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   PANTHER; PTHR20836; DapB_bac/pln; 1.
DR   Pfam; PF05173; DapB_C; 1.
DR   Pfam; PF01113; DapB_N; 1.
DR   ProDom; PD004105; DapB; 1.
DR   TIGRFAMs; TIGR00036; dapB; 1.
DR   PROSITE; PS01298; DAPB; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis; Complete proteome; Cytoplasm;
KW   Diaminopimelate biosynthesis; Lysine biosynthesis; NADP;
KW   Oxidoreductase.
SQ   SEQUENCE   293 AA;  31218 MW;  AD4282444CE33E5D CRC64;
     MTTAVEQKRR EEGAAIGEGT AASEPIPVLV VGALGKMGRE VVRAVAQTPD MKLVGAVARS
     QLGSDIGEVL GLGSLGVEIT DDLAGQLLRL SQRSARGVMV DFTHPRSVYE NVRSAIAFGV
     RPVVGTTGLT PEQVERLRDL ADKSGVGCLI APNFAIGMIL LQQMALQAAQ YFDHVEIVEL
     HHNRKVDAPS GTALQTAQRL GQLGKAFNPP EVEEKELIPG SRGGIPGPNI PIHSVRLPGL
     IAHQEVIFGG MGQTLTLRHD ITDRMAFMPG VILGIRKVLQ LKGLVYGLEQ VLS
//