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Reviewed, UniProtKB/Swiss-Prot Q2JUC0 (CYSC_SYNJA)

Last modified June 16, 2009. Version 19. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Adenylyl-sulfate kinase
    EC=2.7.1.25
Alternative name(s):
    APS kinase
    Adenosine-5'-phosphosulfate kinase
    ATP adenosine-5'-phosphosulfate 3'-phosphotransferase
Gene names
Name: cysC
Ordered Locus Names: CYA_1535
OrganismSynechococcus sp. (strain JA-3-3Ab) (Cyanobacteria bacterium Yellowstone A-Prime) [Complete proteome] [HAMAP]
Taxonomic identifier321327 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaChroococcalesSynechococcus

Protein attributes

Sequence length176 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Catalyzes the synthesis of activated sulfate. HAMAP MF_00065

Catalytic activity

ATP + adenylyl sulfate = ADP + 3'-phosphoadenylyl sulfate. HAMAP MF_00065

Pathway

Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 2/3. HAMAP MF_00065

Sequence similarities

Belongs to the APS kinase family.

Ontologies

Keywords
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   PTMPhosphoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processsulfate assimilation

Inferred from electronic annotation. Source: HAMAP

   Molecular functionATP binding

Inferred from electronic annotation. Source: HAMAP

adenylylsulfate kinase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 176176Adenylyl-sulfate kinase HAMAP MF_00065
PRO_1000057446

Regions

Nucleotide binding12 – 198ATP By similarity

Sites

Active site861Phosphoserine intermediate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q2JUC0-1 [UniParc].

Last modified March 7, 2006. Version 1.
Checksum: E58C17C071C70786

FASTA17619,629
        10         20         30         40         50         60 
MGRRGVTVWF TGLSGAGKTT LSCGVAQQLQ ALGLPVEVLD GDLVRQHLSK ELGFSRADRD 

        70         80         90        100        110        120 
ENVRRIGFVA EMLTRHGVIV LVSAISPYRA TRQEVRQQIG NFIEVFVDAP LEVCEQRDVK 

       130        140        150        160        170 
GLYRKARAGL IRHFTGIDDP YEPPEYPEVV CKTAEQSISE CIDLVMQSLR SHGYLQ 

« Hide

References

[1]"Population level functional diversity in a microbial community revealed by comparative genomic and metagenomic analyses."
Bhaya D., Grossman A.R., Steunou A.-S., Khuri N., Cohan F.M., Hamamura N., Melendrez M.C., Bateson M.M., Ward D.M., Heidelberg J.F.
ISME J. 1:703-713(2007) [PubMed: 18059494] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

CP000239 Genomic DNA. Translation: ABC99700.1.
RefSeqYP_474963.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID3897141.
GenomeReviewsGene locus CYA_1535 in contig CP000239_GR.
KEGGcya:CYA_1535.
TIGRCYA_1535.

Phylogenomic databases

HOGENOMQ2JUC0.
OMAQ2JUC0. IITITAF.

Family and domain databases

HAMAPMF_00065.
[Tree]
InterProIPR002891. APS_kinase_C.
[Graphical view]
PfamPF01583. APS_kinase. 1 hit.
[Graphical view]
ProDomPD002350. APS_kinase. 1 hit.
[Graphical view] [Entries sharing at least one domain]
TIGRFAMsTIGR00455. apsK. 1 hit.
ProtoNetSearch...

Entry information

Entry nameCYSC_SYNJA
AccessionPrimary (citable) accession number: Q2JUC0
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: March 7, 2006
Last modified: June 16, 2009
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents