Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q2JT08 (GLGB_SYNJA) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
1,4-alpha-glucan branching enzyme GlgB

EC=2.4.1.18
Alternative name(s):
1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase
Alpha-(1->4)-glucan branching enzyme
Glycogen branching enzyme
Short name=BE
Gene names
Name:glgB
Ordered Locus Names:CYA_2062
OrganismSynechococcus sp. (strain JA-3-3Ab) (Cyanobacteria bacterium Yellowstone A-Prime) [Complete proteome] [HAMAP]
Taxonomic identifier321327 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechococcus

Protein attributes

Sequence length770 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position By similarity. HAMAP-Rule MF_00685

Catalytic activity

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain. HAMAP-Rule MF_00685

Pathway

Glycan biosynthesis; glycogen biosynthesis. HAMAP-Rule MF_00685

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00685

Sequence similarities

Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 7707701,4-alpha-glucan branching enzyme GlgB HAMAP-Rule MF_00685
PRO_0000260709

Sites

Active site4371Nucleophile By similarity
Active site4881Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
Q2JT08 [UniParc].

Last modified March 7, 2006. Version 1.
Checksum: 007E7EAF14CBEF91

FASTA77089,561
        10         20         30         40         50         60 
MGFLLSAEQV LQFVTNQWQD PYAVLGPQQI EQGETSFWLV RALVPNAKQV WLVERATGQA 

        70         80         90        100        110        120 
YPMQPLHPET LFELCFAPGT PVPDYFLRAQ RVWDPEGQHL EEWEDPYRFP LEKVNHIGEL 

       130        140        150        160        170        180 
DRYLFNEGNH HRIYEKLGAH PISVDGVQGV HFAVWAPNAR NVSVIGDFNH WDGRQHQMKR 

       190        200        210        220        230        240 
LGESGIWAVF IPGVGPGAVY KYEVKTAWGD IYEKSDPYGF QQEVRPKTGS IVADLHTYTW 

       250        260        270        280        290        300 
HDQEWLEKRA ATDPLRSPIS VYEVHLGSWM HASTEDPPAD GHLVPVEQKP NTRFLTYREL 

       310        320        330        340        350        360 
ADKLIPYVKE LGFTHIELLP VAEHPFDGSW GYQVIGYYAV TSRYGSPQDF MYFVDRAHQE 

       370        380        390        400        410        420 
GIGVIVDWVP GHFPKDGHGL AFFDGTHLYE YADPRKGEHK GWGTLVFNYG RNEVRNYLIA 

       430        440        450        460        470        480 
NALFWFDKYH IDGLRVDAVA SMLYLDYDRK EWIPNCYGGR EHLEAIDFFR QLNTLIFKYY 

       490        500        510        520        530        540 
PGVLSIAEES TAWPMVTWPT HVGGLGFNLK WNMGWMHDML NYFRMDPWFR QFHHNLVTFS 

       550        560        570        580        590        600 
LMYAFSENYM LAFSHDEVVH GKSHMLGKMP GDLWHKFASL RALYGYMFTH PGKKTLFMSM 

       610        620        630        640        650        660 
EFGQWNEWNV WADLDWELLQ YEPHAKLRHY VATLNQLLRS QPALYTQDTK PEGFRWIDCS 

       670        680        690        700        710        720 
DHRGIISFIR YGEDPREWLV VVCNFTPVVW PNYRIGVPQR GFYRELLNSD AVEFWGSGVG 

       730        740        750        760        770 
NLGGKWTDDW PYHNLPYSLE LCLPPLSTLV LKWQPPQLAE DSGENKAMLE 

« Hide

References

[1]"Population level functional diversity in a microbial community revealed by comparative genomic and metagenomic analyses."
Bhaya D., Grossman A.R., Steunou A.-S., Khuri N., Cohan F.M., Hamamura N., Melendrez M.C., Bateson M.M., Ward D.M., Heidelberg J.F.
ISME J. 1:703-713(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: JA-3-3Ab.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000239 Genomic DNA. Translation: ABD00202.1.
RefSeqYP_475465.1. NC_007775.1.

3D structure databases

ProteinModelPortalQ2JT08.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING321327.CYA_2062.

Protein family/group databases

CAZyCBM48. Carbohydrate-Binding Module Family 48.
GH13. Glycoside Hydrolase Family 13.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABD00202; ABD00202; CYA_2062.
GeneID3899245.
KEGGcya:CYA_2062.
PATRIC23812402. VBISynSp90045_2036.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0296.
HOGENOMHOG000283037.
KOK00700.
OMAAKLLFMG.
OrthoDBEOG6JX7GT.

Enzyme and pathway databases

BioCycSSP321327:GHFX-2054-MONOMER.
UniPathwayUPA00164.

Family and domain databases

Gene3D2.60.40.10. 2 hits.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
HAMAPMF_00685. GlgB.
InterProIPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERPTHR10357. PTHR10357. 1 hit.
PfamPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view]
PIRSFPIRSF000463. GlgB. 1 hit.
SUPFAMSSF51445. SSF51445. 1 hit.
SSF81296. SSF81296. 2 hits.
TIGRFAMsTIGR01515. branching_enzym. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLGB_SYNJA
AccessionPrimary (citable) accession number: Q2JT08
Entry history
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: March 7, 2006
Last modified: June 11, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries