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Q2JRE8 (Q2JRE8_SYNJA) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase HAMAP MF_01840
Short name=Mg-protoporphyrin IX monomethyl ester oxidative cyclase HAMAP MF_01840
EC=1.14.13.81 HAMAP MF_01840
Gene names
Name:acsF HAMAP MF_01840
Ordered Locus Names:CYA_2703
OrganismSynechococcus sp. (strain JA-3-3Ab) (Cyanobacteria bacterium Yellowstone A-Prime) [Complete proteome] [HAMAP]
Taxonomic identifier321327 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Chroococcales › Synechococcus

Protein attributes

Sequence length363 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) By similarity. HAMAP MF_01840

Catalytic activity

131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = 131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + 2 H2O. HAMAP MF_01840

131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = divinylprotochlorophyllide + NADP+ + 2 H2O. HAMAP MF_01840

Magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = 131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O. HAMAP MF_01840

Cofactor

Iron By similarity. HAMAP MF_01840

Pathway

Porphyrin biosynthesis; chlorophyll biosynthesis (light-independent). HAMAP MF_01840

Sequence similarities

Belongs to the AcsF family. HAMAP MF_01840

Sequences

Sequence LengthMass (Da)Tools
Q2JRE8 [UniParc].

Last modified March 7, 2006. Version 1.
Checksum: ECD73C94D37B26CF

FASTA36342,922
        10         20         30         40         50         60 
MSSTLRAAQT QARVPTETIL TPRFYTTDFE AIGKMGLGDR EADFRAILEE FRADYNRHHF 

        70         80         90        100        110        120 
VRGEEFNQDW ESRLDPEARR LFVEFLERSC TAEFSGFLLY KELSRRLKET NPVLAECFAL 

       130        140        150        160        170        180 
MSRDEARHAG FLNRAMGDFN MAFDLGFLTK HKSYTYFAPR FIFYATYLSE KIGYWRYILI 

       190        200        210        220        230        240 
YRHLEAHPEN RVYPIFNFFK NWCQDENRHG DFFALMLLSQ PRLLEGWVAE LWCRFFLLSV 

       250        260        270        280        290        300 
FATMYLNDVG ERPGFYRLLG LDPHTYDMEV IYKTNREAAK VFPVVLDVEN PEFVRRLQKC 

       310        320        330        340        350        360 
VANNAKLREI ARGAGPFKSL RKLPLYLNNA YQFLRLFLLK PRKAGFYLWE QPEPRFEGTA 


VSA

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References

[1]"Population level functional diversity in a microbial community revealed by comparative genomic and metagenomic analyses."
Bhaya D., Grossman A.R., Steunou A.-S., Khuri N., Cohan F.M., Hamamura N., Melendrez M.C., Bateson M.M., Ward D.M., Heidelberg J.F.
ISME J. 1:703-713(2007) [PubMed: 18059494] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: JA-3-3Ab.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000239 Genomic DNA. Translation: ABD00811.1.
RefSeqYP_476074.1. NC_007775.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ2JRE8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3899354.
GenomeReviewsGene locus CYA_2703 in contig CP000239_GR.
KEGGcya:CYA_2703.
PATRIC23813666. VBISynSp90045_2658.
TIGRCYA_2703.

Phylogenomic databases

eggNOGNOG10633.
HOGENOMHBG284843.
OMAHGDFFDA.
PhylomeDBQ2JRE8.
ProtClustDBPRK13654.

Enzyme and pathway databases

BioCycSSP321327:CYA_2703-MONOMER.

Family and domain databases

HAMAPMF_01840. AcsF.
[Tree]
InterProIPR008434. AcsF.
IPR012347. Ferritin-rel.
IPR009078. Ferritin/RR-like.
IPR003251. Rubrerythrin.
[Graphical view]
Gene3DG3DSA:1.20.1260.10. Ferritin_rel. 1 hit.
KOK04035.
PfamPF02915. Rubrerythrin. 1 hit.
[Graphical view]
SUPFAMSSF47240. Ferritin/RR_like. 1 hit.
TIGRFAMsTIGR02029. AcsF. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ2JRE8_SYNJA
AccessionPrimary (citable) accession number: Q2JRE8
Entry history
Integrated into UniProtKB/TrEMBL: March 7, 2006
Last sequence update: March 7, 2006
Last modified: January 25, 2012
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info