ID   Q2JQG2_SYNJA            Unreviewed;       643 AA.
AC   Q2JQG2;
DT   07-MAR-2006, integrated into UniProtKB/TrEMBL.
DT   07-MAR-2006, sequence version 1.
DT   27-MAR-2024, entry version 82.
DE   SubName: Full=Serine/threonine protein kinase {ECO:0000313|EMBL:ABD00286.1};
DE            EC=2.7.11.1 {ECO:0000313|EMBL:ABD00286.1};
GN   OrderedLocusNames=CYA_2146 {ECO:0000313|EMBL:ABD00286.1};
OS   Synechococcus sp. (strain JA-3-3Ab) (Cyanobacteria bacterium Yellowstone
OS   A-Prime).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Synechococcales; Synechococcaceae;
OC   Synechococcus.
OX   NCBI_TaxID=321327 {ECO:0000313|EMBL:ABD00286.1, ECO:0000313|Proteomes:UP000008818};
RN   [1] {ECO:0000313|EMBL:ABD00286.1, ECO:0000313|Proteomes:UP000008818}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JA-3-3Ab {ECO:0000313|EMBL:ABD00286.1,
RC   ECO:0000313|Proteomes:UP000008818};
RX   PubMed=18059494; DOI=10.1038/ismej.2007.46;
RA   Bhaya D., Grossman A.R., Steunou A.S., Khuri N., Cohan F.M., Hamamura N.,
RA   Melendrez M.C., Bateson M.M., Ward D.M., Heidelberg J.F.;
RT   "Population level functional diversity in a microbial community revealed by
RT   comparative genomic and metagenomic analyses.";
RL   ISME J. 1:703-713(2007).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC         [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC         COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC         Evidence={ECO:0000256|ARBA:ARBA00001433};
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC         threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC         Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC         EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
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DR   EMBL; CP000239; ABD00286.1; -; Genomic_DNA.
DR   RefSeq; WP_011430960.1; NC_007775.1.
DR   AlphaFoldDB; Q2JQG2; -.
DR   STRING; 321327.CYA_2146; -.
DR   KEGG; cya:CYA_2146; -.
DR   eggNOG; COG0515; Bacteria.
DR   HOGENOM; CLU_445333_0_0_3; -.
DR   Proteomes; UP000008818; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0106310; F:protein serine kinase activity; IEA:RHEA.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   GO; GO:0010506; P:regulation of autophagy; IEA:InterPro.
DR   CDD; cd14014; STKc_PknB_like; 1.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR045269; Atg1-like.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR008271; Ser/Thr_kinase_AS.
DR   PANTHER; PTHR24348:SF22; NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE; 1.
DR   PANTHER; PTHR24348; SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED; 1.
DR   Pfam; PF00069; Pkinase; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000313|EMBL:ABD00286.1};
KW   Serine/threonine-protein kinase {ECO:0000313|EMBL:ABD00286.1};
KW   Transferase {ECO:0000313|EMBL:ABD00286.1}.
FT   DOMAIN          21..274
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
SQ   SEQUENCE   643 AA;  71485 MW;  44B46E7F221E16C0 CRC64;
     MDSPGAVSRR TRTTKSIHDS YQILGLAGQG QYGRVFCARP RHGGDLVALK ELPAERFPTP
     NLLRELRYLL TLNHPNITRC YALEHAREGR YLVLEYCEGG TLRELIDQVE RGLWLPVKQV
     LGFVDQILAG LDHAHRQGVI HCDVKPENIL LKPTPQGWQL KLTDFGIARH PQPAPGEISA
     TGSPAYMAPE RFYGQFSPAS DLYAVGIILL ELLTGRRPFS GSPSQLMHAH LNQPFVCPEG
     IPAPLQELLE ITLRKLPLRR FRTAAQMRSA LATFAREWQE PAGCWVGPRL SRRSPPGLQV
     WDLPDPGFVG EGGRESLPEQ KFCICEDPSG SRSPLLLRVT PQRLEWLDLQ TLASGAPPLA
     CFSLAEPLQQ VLPLPSFPEA LAFSKSNLLH LSPARVRTLL SFAEDWRATW LAERQELVWA
     TAKEIGAVQW LPAGPTVAQP FPEFHCYFRW PWQVPTGSLL RLLALSEHLV LLAGLGRQWV
     EMTVLPYPAA WPPQTGSQPL RYRLPLDPRG RVLSLGERLL FAGGDGGGQG CCPHLCSVQV
     NPLRLRRWFL KGWPLQMAKA PWGVLLLCRE GEEFSSLWLY SEGGYPLAQV AVPVGSEVLQ
     VGQRGLVWLQ VPKAGKPQQF QLWQLDLNQL PANGHAAEGV ALG
//