Q2JP62 (Q2JP62_SYNJB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphoadenosine phosphosulfate reductase HAMAP MF_00063
EC=1.8.4.8 HAMAP MF_00063

Alternative name(s):
3'-phosphoadenylylsulfate reductase HAMAP MF_00063
PAPS reductase, thioredoxin dependent HAMAP MF_00063
PAPS sulfotransferase HAMAP MF_00063
PAdoPS reductase HAMAP MF_00063

Gene names

Name:	cysH HAMAP MF_00063
Ordered Locus Names:	CYB_0438

Organism

Synechococcus sp. (strain JA-2-3B'a(2-13)) (Cyanobacteria bacterium Yellowstone B-Prime) [Complete proteome] [HAMAP]

Taxonomic identifier

321332 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechococcus

Protein attributes

Sequence length	248 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Reduction of activated sulfate into sulfite By similarity. HAMAP MF_00063 SAAS SAAS002500
Catalytic activity	Adenosine 3',5'-bisphosphate + sulfite + thioredoxin disulfide = 3'-phosphoadenylyl sulfate + thioredoxin. HAMAP MF_00063 SAAS SAAS002500
Pathway	Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 3/3. HAMAP MF_00063 SAAS SAAS002500
Subcellular location	Cytoplasm By similarity HAMAP MF_00063 SAAS SAAS002500.
Sequence similarities	Belongs to the PAPS reductase family. CysH subfamily. HAMAP MF_00063

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_00063 SAAS SAAS002500
Molecular function	Oxidoreductase HAMAP MF_00063 SAAS SAAS002500 EMBL ABD01433.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	phosphoadenylyl-sulfate reductase (thioredoxin) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q2JP62 [UniParc]. Last modified March 7, 2006. Version 1. Checksum: FE42396F5E7CA39E	FASTA	248	28,078
	10 20 30 40 50 60 MTASLSPSSR WELAAQALRE QYQPQVASLS ERFEPLSASD LLTWAVEEFG DGLVLACSFG 70 80 90 100 110 120 PEDLVLIDLL TAINPRVRAF FLDTDFHFPE TLQLREQVLA RYPHLQLQIF KPLLTPEEQA 130 140 150 160 170 180 AQYGPELYRS NPDLCCNIRK VEPLNRALAG CTTWITGMRR EQSPTRADIG KVQWDGKRNR 190 200 210 220 230 240 LKLNPLADWT NGQVWKYILD HGIPYNPLHD RHYPSIGCLH CTAPVEPGAD PRSGRWKGTS KTECGLHT

References

[1]

"Population level functional diversity in a microbial community revealed by comparative genomic and metagenomic analyses." Bhaya D., Grossman A.R., Steunou A.-S., Khuri N., Cohan F.M., Hamamura N., Melendrez M.C., Bateson M.M., Ward D.M., Heidelberg J.F. ISME J. 1:703-713(2007) [PubMed: 18059494] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: JA-2-3B'a(2-13).

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000240 Genomic DNA. Translation: ABD01433.1.
RefSeq	YP_476696.1. NC_007776.1.
3D structure databases
ProteinModelPortal	Q2JP62.
ModBase	Search...
Protein-protein interaction databases
STRING	Q2JP62.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3900516.
GenomeReviews	Gene locus CYB_0438 in contig CP000240_GR.
KEGG	cyb:CYB_0438.
PATRIC	23803166. VBISynSp29577_0448.
TIGR	CYB_0438.
Phylogenomic databases
eggNOG	COG0175.
HOGENOM	HBG758022.
OMA	QVKSYID.
PhylomeDB	Q2JP62.
ProtClustDB	CLSK423129.
Enzyme and pathway databases
BioCyc	SSP321332:CYB_0438-MONOMER.
Family and domain databases
HAMAP	MF_00063. CysH. [Tree]
InterPro	IPR004511. PAPS/APS_Rdtase. IPR002500. PAPS_reduct. IPR014729. Rossmann-like_a/b/a_fold. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
KO	K00390.
Pfam	PF01507. PAPS_reduct. 1 hit. [Graphical view]
PIRSF	PIRSF000857. PAPS_reductase. 1 hit.
TIGRFAMs	TIGR00434. CysH. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q2JP62_SYNJB

Accession

Primary (citable) accession number: Q2JP62

Entry history

Integrated into UniProtKB/TrEMBL:	March 7, 2006
Last sequence update:	March 7, 2006
Last modified:	January 25, 2012
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)