Q2JN73 (Q2JN73_SYNJB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Ornithine carbamoyltransferase HAMAP-Rule MF_01109
Short name=OTCase HAMAP-Rule MF_01109
EC=2.1.3.3 HAMAP-Rule MF_01109

Gene names

Name:	argF HAMAP-Rule MF_01109
Ordered Locus Names:	CYB_0821

Organism

Synechococcus sp. (strain JA-2-3B'a(2-13)) (Cyanobacteria bacterium Yellowstone B-Prime) [Complete proteome] [HAMAP] EMBL ABD01802.1

Taxonomic identifier

321332 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Cyanobacteria › Oscillatoriophycideae › Chroococcales › Synechococcus

Protein attributes

Sequence length	314 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Carbamoyl phosphate + L-ornithine = phosphate + L-citrulline. HAMAP-Rule MF_01109 SAAS SAAS002292
Pathway	Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 1/3. HAMAP-Rule MF_01109
Subcellular location	Cytoplasm By similarity SAAS SAAS002292 HAMAP-Rule MF_01109.
Sequence similarities	Belongs to the ATCase/OTCase family. HAMAP-Rule MF_01109 RuleBase RU003634

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Arginine biosynthesis HAMAP-Rule MF_01109
Cellular component	Cytoplasm SAAS SAAS002292 HAMAP-Rule MF_01109
Molecular function	Transferase SAAS SAAS002292 HAMAP-Rule MF_01109 RuleBase RU003634 EMBL ABD01802.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	arginine biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	amino acid binding Inferred from electronic annotation. Source: InterPro ornithine carbamoyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Region	60 – 64	5	Carbamoyl phosphate binding By similarity HAMAP-Rule MF_01109
	Region	270 – 273	4	Ornithine binding By similarity HAMAP-Rule MF_01109
Sites
	Binding site	111	1	Carbamoyl phosphate By similarity HAMAP-Rule MF_01109
	Binding site	138	1	Carbamoyl phosphate By similarity HAMAP-Rule MF_01109
	Site	39	1	Important for structural integrity By similarity HAMAP-Rule MF_01109
	Site	151	1	Important for structural integrity By similarity HAMAP-Rule MF_01109

Sequences

	Sequence		Length	Mass (Da)
	Q2JN73 [UniParc]. Last modified March 7, 2006. Version 1. Checksum: CE261C85C0F9C929	FASTA	314	33,959
	10 20 30 40 50 60 MAGSKIAGSI NLAGRDLLKL SDLTPAELSA LLAQAAELKR DPYRVELRGR VLGLLFQKAS 70 80 90 100 110 120 TRTRASFTAA MAQCGGSTLD LVPTVMQVSR GEPLQDTARV LSRYLDVIAI RTYDQKELET 130 140 150 160 170 180 FAEYADVPVI NALTDQFHPC QVLADLLTIQ ENFGQLAGLT LAYCGDGNNV AHSLLLGCAM 190 200 210 220 230 240 SGIHIRVATP PGYEPDAAVV EQARTLAQGS QVLVLQDPQE AVSGSQVVYT DVWASMGQEA 250 260 270 280 290 300 EAEARKATFL PYQVNAELLQ RADPQAIVLH CLPAHREEEI TTEVLEGSQS RVWDQAENRL 310 HVQKALLIQV LGAG

References

[1]

"Population level functional diversity in a microbial community revealed by comparative genomic and metagenomic analyses." Bhaya D., Grossman A.R., Steunou A.-S., Khuri N., Cohan F.M., Hamamura N., Melendrez M.C., Bateson M.M., Ward D.M., Heidelberg J.F. ISME J. 1:703-713(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: JA-2-3B'a(2-13).

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000240 Genomic DNA. Translation: ABD01802.1.
RefSeq	YP_477065.1. NC_007776.1.
3D structure databases
ProteinModelPortal	Q2JN73.
SMR	Q2JN73. Positions 14-313.
ModBase	Search...
Protein-protein interaction databases
STRING	321332.CYB_0821.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABD01802; ABD01802; CYB_0821.
GeneID	3902336.
KEGG	cyb:CYB_0821.
PATRIC	23803940. VBISynSp29577_0828.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0078.
HOGENOM	HOG000022686.
KO	K00611.
OMA	KHLLSIK.
ProtClustDB	PRK00779.
Enzyme and pathway databases
UniPathway	UPA00068; UER00112.
Family and domain databases
HAMAP	MF_01109. OTCase.
InterPro	IPR006132. Asp/Orn_carbamoyltranf_P-bd. IPR006130. Asp/Orn_carbamoylTrfase. IPR006131. Asp_carbamoyltransf_Asp/Orn-bd. IPR002292. Orn/put_carbamltrans. IPR024904. Orn_carbamltrans. [Graphical view]
Pfam	PF00185. OTCace. 1 hit. PF02729. OTCace_N. 1 hit. [Graphical view]
PRINTS	PR00100. AOTCASE. PR00102. OTCASE.
SUPFAM	SSF53671. Asp/Orn_carbamoyltranf. 1 hit.
TIGRFAMs	TIGR00658. orni_carb_tr. 1 hit.
PROSITE	PS00097. CARBAMOYLTRANSFERASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q2JN73_SYNJB

Accession

Primary (citable) accession number: Q2JN73

Entry history

Integrated into UniProtKB/TrEMBL:	March 7, 2006
Last sequence update:	March 7, 2006
Last modified:	May 1, 2013
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)