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Protein
Submitted name:

Sensor histidine kinase

Gene

CYB_2465

Organism
Synechococcus sp. (strain JA-2-3B'a(2-13)) (Cyanobacteria bacterium Yellowstone B-Prime)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei138 – 1381Phycocyanobilin chromophore 1 (covalent)Combined sources
Binding sitei138 – 1381Phycocyanobilin chromophore 2 (covalent)Combined sources
Binding sitei138 – 1381Phycocyanobilin chromophore 3 (covalent)Combined sources
Binding sitei138 – 1381Phycocyanobilin chromophore 4 (covalent)Combined sources
Binding sitei138 – 1381Phycocyanobilin chromophore 5 (covalent)Combined sources

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseSAAS annotationImported, Photoreceptor proteinUniRule annotation, Receptor, Transferase

Keywords - Biological processi

Sensory transduction

Keywords - Ligandi

Chromophore

Enzyme and pathway databases

BioCyciSSP321332:GH1B-2465-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Sensor histidine kinaseImported
Gene namesi
Ordered Locus Names:CYB_2465Imported
OrganismiSynechococcus sp. (strain JA-2-3B'a(2-13)) (Cyanobacteria bacterium Yellowstone B-Prime)Imported
Taxonomic identifieri321332 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechococcus
Proteomesi
  • UP000001938 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi321332.CYB_2465.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2K2NNMR-A31-200[»]
2KLINMR-A31-200[»]
2KOINMR-A31-200[»]
2LB5NMR-A1-200[»]
2LB9NMR-A1-200[»]
ProteinModelPortaliQ2JIZ5.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ2JIZ5.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini30 – 190161PHYTOCHROME_2InterPro annotationAdd
BLAST
Domaini605 – 821217Histidine kinaseInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili397 – 42428Sequence analysisAdd
BLAST

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG4108K25. Bacteria.
ENOG410XNUV. LUCA.
HOGENOMiHOG000127720.
OMAiLINRITH.
OrthoDBiEOG69GZGV.

Family and domain databases

Gene3Di1.10.287.130. 1 hit.
3.30.450.40. 2 hits.
3.30.565.10. 1 hit.
InterProiIPR003018. GAF.
IPR029016. GAF_dom-like.
IPR003594. HATPase_C.
IPR005467. His_kinase_dom.
IPR003661. HisK_dim/P.
IPR016132. Phyto_chromo_attachment.
IPR013515. Phytochrome_cen-reg.
IPR004358. Sig_transdc_His_kin-like_C.
[Graphical view]
PfamiPF01590. GAF. 2 hits.
PF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
PF00360. PHY. 1 hit.
[Graphical view]
PRINTSiPR00344. BCTRLSENSOR.
SMARTiSM00065. GAF. 3 hits.
SM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
[Graphical view]
SUPFAMiSSF47384. SSF47384. 1 hit.
SSF55781. SSF55781. 3 hits.
SSF55874. SSF55874. 1 hit.
PROSITEiPS50109. HIS_KIN. 1 hit.
PS50046. PHYTOCHROME_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2JIZ5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDTETWAAAA RPSRDALINR ITHQIRQSLE LDQILRATVE EVRAFLGTDR
60 70 80 90 100
VKVYRFDPEG HGTVVAEARG GERLPSLLGL TFPAGDIPEE ARRLFRLAQV
110 120 130 140 150
RVIVDVEAQS RSISQPESWG LSARVPLGEP LQRPVDPCHV HYLKSMGVAS
160 170 180 190 200
SLVVPLMHHQ ELWGLLVSHH AEPRPYSQEE LQVVQLLADQ VSIAIAQAEL
210 220 230 240 250
LEQARQKAQQ ERLINQIAAL VYSPLHPETT LTTVLEQLAA GLQGIGARLR
260 270 280 290 300
IHFMGADTLC CHGVQPPASY DTWLQEQLGR AGGAGGWVKM WSLSHLEKWP
310 320 330 340 350
ELQEQMKQTP IRGLLVAQLA WNDQPVGWLS VFRGAVYQET HWAGYRWFTQ
360 370 380 390 400
GDPRQELPLI SFAAWRELKI DEPKAWSAAE QELMSRVGVH LALSITQNQL
410 420 430 440 450
YRQLQTLNAR LEQEVQERTA ALQRSLAMDA LLQRVTDQVR SSLEEAQILR
460 470 480 490 500
AVVQELALGL PIQGCDLCLY DWASGQATVR YEYTSALPPA GGITLTLADY
510 520 530 540 550
PDLYRHLQGG QAVQFCHLPG QGWIPRREGL TLLVCPLRDD QGVLGDLWLA
560 570 580 590 600
KPAAKCFDEL EVQVVQQVAD HCAIAIRQAR LYQASVQQIG ELERLNRLKD
610 620 630 640 650
DFLSTVSHEL RTPITNMRMA IQLLKTARAP QKREQYLKIL EQECEREAEL
660 670 680 690 700
VNDLLDLQRL EQGSKTLHLE EVPLATWLPS VLEPFLQRAQ VNQQRLQWQI
710 720 730 740 750
APNVGKVLTD QGGLERVVQE LVNNACKYTP PGCSIWVTAQ RPGPQQVEIR
760 770 780 790 800
VINEGVEISP AEQERIFEKF YRIPSGDPWK RGGTGLGLAL VKQWMQRLGG
810 820 830
SVSVESSQGK TCFTLVLPQG SLPVQTSPLA HNCA
Length:834
Mass (Da):93,467
Last modified:March 7, 2006 - v1
Checksum:i8F8CC15B9F47EC7B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000240 Genomic DNA. Translation: ABD03399.1.
RefSeqiWP_011434028.1. NC_007776.1.

Genome annotation databases

EnsemblBacteriaiABD03399; ABD03399; CYB_2465.
KEGGicyb:CYB_2465.
PATRICi23807278. VBISynSp29577_2464.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000240 Genomic DNA. Translation: ABD03399.1.
RefSeqiWP_011434028.1. NC_007776.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2K2NNMR-A31-200[»]
2KLINMR-A31-200[»]
2KOINMR-A31-200[»]
2LB5NMR-A1-200[»]
2LB9NMR-A1-200[»]
ProteinModelPortaliQ2JIZ5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi321332.CYB_2465.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABD03399; ABD03399; CYB_2465.
KEGGicyb:CYB_2465.
PATRICi23807278. VBISynSp29577_2464.

Phylogenomic databases

eggNOGiENOG4108K25. Bacteria.
ENOG410XNUV. LUCA.
HOGENOMiHOG000127720.
OMAiLINRITH.
OrthoDBiEOG69GZGV.

Enzyme and pathway databases

BioCyciSSP321332:GH1B-2465-MONOMER.

Miscellaneous databases

EvolutionaryTraceiQ2JIZ5.

Family and domain databases

Gene3Di1.10.287.130. 1 hit.
3.30.450.40. 2 hits.
3.30.565.10. 1 hit.
InterProiIPR003018. GAF.
IPR029016. GAF_dom-like.
IPR003594. HATPase_C.
IPR005467. His_kinase_dom.
IPR003661. HisK_dim/P.
IPR016132. Phyto_chromo_attachment.
IPR013515. Phytochrome_cen-reg.
IPR004358. Sig_transdc_His_kin-like_C.
[Graphical view]
PfamiPF01590. GAF. 2 hits.
PF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
PF00360. PHY. 1 hit.
[Graphical view]
PRINTSiPR00344. BCTRLSENSOR.
SMARTiSM00065. GAF. 3 hits.
SM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
[Graphical view]
SUPFAMiSSF47384. SSF47384. 1 hit.
SSF55781. SSF55781. 3 hits.
SSF55874. SSF55874. 1 hit.
PROSITEiPS50109. HIS_KIN. 1 hit.
PS50046. PHYTOCHROME_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Population level functional diversity in a microbial community revealed by comparative genomic and metagenomic analyses."
    Bhaya D., Grossman A.R., Steunou A.S., Khuri N., Cohan F.M., Hamamura N., Melendrez M.C., Bateson M.M., Ward D.M., Heidelberg J.F.
    ISME J. 1:703-713(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JA-2-3B'a(2-13)Imported.
  2. "Solution structure of a cyanobacterial phytochrome GAF domain in the red-light-absorbing ground state."
    Cornilescu G., Ulijasz A.T., Cornilescu C.C., Markley J.L., Vierstra R.D.
    J. Mol. Biol. 383:403-413(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: STRUCTURE BY NMR OF 1-200 IN COMPLEX WITH PHYCOCYANOBILIN CHROMOPHORE.
  3. "Structural basis for the photoconversion of a phytochrome to the activated Pfr form."
    Ulijasz A.T., Cornilescu G., Cornilescu C.C., Zhang J., Rivera M., Markley J.L., Vierstra R.D.
    Nature 463:250-254(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: STRUCTURE BY NMR OF 1-200 IN COMPLEX WITH PHYCOCYANOBILIN CHROMOPHORE.

Entry informationi

Entry nameiQ2JIZ5_SYNJB
AccessioniPrimary (citable) accession number: Q2JIZ5
Entry historyi
Integrated into UniProtKB/TrEMBL: March 7, 2006
Last sequence update: March 7, 2006
Last modified: July 6, 2016
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.