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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Frankia casuarinae (strain DSM 45818 / CECT 9043 / CcI3)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgi)
  3. Pyrophosphate--fructose 6-phosphate 1-phosphotransferase (pfp), ATP-dependent 6-phosphofructokinase (pfkA)
  4. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei363Proton donorUniRule annotation1
Active sitei394UniRule annotation1
Active sitei522UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processGluconeogenesis, Glycolysis

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:Francci3_0045
OrganismiFrankia casuarinae (strain DSM 45818 / CECT 9043 / CcI3)
Taxonomic identifieri106370 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaFrankialesFrankiaceaeFrankia
Proteomesi
  • UP000001937 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002526221 – 556Glucose-6-phosphate isomeraseAdd BLAST556

Interactioni

Protein-protein interaction databases

STRINGi106370.Francci3_0045.

Structurei

3D structure databases

ProteinModelPortaliQ2JH03.
SMRiQ2JH03.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107QP8. Bacteria.
COG0166. LUCA.
HOGENOMiHOG000261370.
KOiK01810.
OMAiTNSQHAF.
OrthoDBiPOG091H04C3.

Family and domain databases

CDDicd05015. SIS_PGI_1. 1 hit.
cd05016. SIS_PGI_2. 1 hit.
Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase. 1 hit.
InterProiView protein in InterPro
IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
IPR035476. SIS_PGI_1.
IPR035482. SIS_PGI_2.
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiView protein in Pfam
PF00342. PGI. 1 hit.
PRINTSiPR00662. G6PISOMERASE.
PROSITEiView protein in PROSITE
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2JH03-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTTEPAAPV APLDITATEE WAALTTHLRE ISEVSLRDLF AADPRRGETF
60 70 80 90 100
AAEADGLYLD YSKNRLTART VELLTALARR AGLADRIEAM FRGERINVTE
110 120 130 140 150
NRPVLHVALR APAGTRIEVD GVDVVPDVHR VLDAMSQFAD RVRSGDWLGA
160 170 180 190 200
TGERIRTVVN IGIGGSDLGP AMAYDALRDY ADRSIEVRFV SNVDPTDIWE
210 220 230 240 250
ATADLDPAST LFIVSSKTFT TLETISNARA ARSWLTGLLG EDAVSRHFVA
260 270 280 290 300
VSTNAEKVAE FGIDTVNMFE FWDWVGGRYS VDCAIGLSLM IAIGPPNFRE
310 320 330 340 350
FLAGFAAMDT HFRTAPFERN LPVLLGLIGL WYRDFFGTAT HAVLPYSHYL
360 370 380 390 400
GRFPAYLQQL DMESNGKSVD LTGRPVSTPT GPIVWGTPGT NGQHAYYQLL
410 420 430 440 450
HQGTTIVPAD FIGFVRPNHP GVGTADGAGV DQHALLLANF LAQTEALAFG
460 470 480 490 500
RTAAEVAAEG VTPDLVAHRT FPGNRPSNTL LAQKLTPFAL GQLIALYEHK
510 520 530 540 550
VFTQGVIWGI NSFDQWGVEL GKVLAGRIIP ELGSEQEPEL GHDSSTNALI

KRLRAG
Length:556
Mass (Da):60,424
Last modified:March 7, 2006 - v1
Checksum:i38F6F4CD01D177A1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000249 Genomic DNA. Translation: ABD09439.1.
RefSeqiWP_011434521.1. NC_007777.1.

Genome annotation databases

EnsemblBacteriaiABD09439; ABD09439; Francci3_0045.
GeneIDi32155082.
KEGGifra:Francci3_0045.

Similar proteinsi

Entry informationi

Entry nameiG6PI_FRACC
AccessioniPrimary (citable) accession number: Q2JH03
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: March 7, 2006
Last modified: August 30, 2017
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families