Q2JFE2 (GLMM_FRASC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase
EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	Francci3_0616

Organism

Frankia sp. (strain CcI3) [Complete proteome] [HAMAP]

Taxonomic identifier

106370 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Frankineae › Frankiaceae › Frankia

Protein attributes

Sequence length	455 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554_B
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554_B
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554_B
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554_B
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoglucosamine mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 455	455	Phosphoglucosamine mutase HAMAP MF_01554_B		PRO_0000301318
Sites
	Active site	108	1	Phosphoserine intermediate By similarity
	Metal binding	108	1	Magnesium; via phosphate group By similarity
	Metal binding	246	1	Magnesium By similarity
	Metal binding	248	1	Magnesium By similarity
	Metal binding	250	1	Magnesium By similarity
Amino acid modifications
	Modified residue	108	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q2JFE2 [UniParc]. Last modified March 7, 2006. Version 1. Checksum: 4A546637B9F1D0AC	FASTA	455	46,587
	10 20 30 40 50 60 MVRLFGTDGV RGVANIDLTA EQALSLASAA VEVLAGPNRT SGPSGRGKPV VVVGRDTRPS 70 80 90 100 110 120 GEFLEAAVVA GLAASGADVA RIGVAPTPAV AHAVAASGAM FGVMLSASHN PMPDNGIKLF 130 140 150 160 170 180 AAGGLKLPDE VEDAIERRMA LPPSRRPVGA DVGRVRDEPV LLDRYAAHLL ATLPVPLDGL 190 200 210 220 230 240 RVVVDCAQGA ASTLAPRVLR AAGADVVALH ADGDGIAIND GSGATHLDSL RAAVVAHGAD 250 260 270 280 290 300 VGIAHDGDAD RCLAVDATGE VVDGDQILAM CALALAERGE LVDDTVVVTV MSNLGFHHAM 310 320 330 340 350 360 REAGITVVTT PVGDRYVLET MRAGGYVLGG EQSGHVVFLD HATTGDGLLT ALRILGRVAE 370 380 390 400 410 420 TGQPLGELTK AMTRLPQVLV NVRGVDRTQV DTNEELLRAV ALAKAELGDE GRVLLRSSGT 430 440 450 EPLVRVMVEA GTDAAARAVA QRLAAVVRTA LPPAR

References

[1]

"Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography." Normand P., Lapierre P., Tisa L.S., Gogarten J.P., Alloisio N., Bagnarol E., Bassi C.A., Berry A.M., Bickhart D.M., Choisne N., Couloux A., Cournoyer B., Cruveiller S., Daubin V., Demange N., Francino M.P., Goltsman E., Huang Y. , Kopp O.R., Labarre L., Lapidus A., Lavire C., Marechal J., Martinez M., Mastronunzio J.E., Mullin B.C., Niemann J., Pujic P., Rawnsley T., Rouy Z., Schenowitz C., Sellstedt A., Tavares F., Tomkins J.P., Vallenet D., Valverde C., Wall L.G., Wang Y., Medigue C., Benson D.R. Genome Res. 17:7-15(2007) [PubMed: 17151343] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CcI3.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000249 Genomic DNA. Translation: ABD10000.1.
RefSeq	YP_479729.1. NC_007777.1.
3D structure databases
ProteinModelPortal	Q2JFE2.
ModBase	Search...
Protein-protein interaction databases
STRING	Q2JFE2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3903484.
GenomeReviews	Gene locus Francci3_0616 in contig CP000249_GR.
KEGG	fra:Francci3_0616.
PATRIC	21924100. VBIFraSp10456_0675.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1109.
HOGENOM	HBG644964.
OMA	LENTIPE.
PhylomeDB	Q2JFE2.
ProtClustDB	PRK14318.
Enzyme and pathway databases
BioCyc	FSP106370:FRANCCI3_0616-MONOMER.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
KO	K03431.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
TIGRFAMs	TIGR01455. GlmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_FRASC

Accession

Primary (citable) accession number: Q2JFE2

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	March 7, 2006
Last modified:	January 25, 2012
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program