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Protein

Urease subunit beta

Gene

ureB

Organism
Frankia sp. (strain CcI3)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Urea + H2O = CO2 + 2 NH3.UniRule annotation

Pathwayi: urea degradation

This protein is involved in step 1 of the subpathway that synthesizes CO(2) and NH(3) from urea (urease route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Urease subunit alpha (ureC), Urease subunit beta (ureB), Urease subunit gamma (ureA)
This subpathway is part of the pathway urea degradation, which is itself part of Nitrogen metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes CO(2) and NH(3) from urea (urease route), the pathway urea degradation and in Nitrogen metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

UniPathwayiUPA00258; UER00370.

Names & Taxonomyi

Protein namesi
Recommended name:
Urease subunit betaUniRule annotation (EC:3.5.1.5UniRule annotation)
Alternative name(s):
Urea amidohydrolase subunit betaUniRule annotation
Gene namesi
Name:ureBUniRule annotation
Ordered Locus Names:Francci3_0833
OrganismiFrankia sp. (strain CcI3)
Taxonomic identifieri106370 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaFrankialesFrankiaceaeFrankia
Proteomesi
  • UP000001937 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002398921 – 126Urease subunit betaAdd BLAST126

Interactioni

Subunit structurei

Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.UniRule annotation

Protein-protein interaction databases

STRINGi106370.Francci3_0833.

Structurei

3D structure databases

ProteinModelPortaliQ2JES5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the urease beta subunit family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105KI2. Bacteria.
COG0832. LUCA.
HOGENOMiHOG000077770.
KOiK01429.
OMAiREVYGFQ.
OrthoDBiPOG091H08S9.

Family and domain databases

CDDicd00407. Urease_beta. 1 hit.
Gene3Di2.10.150.10. 1 hit.
HAMAPiMF_01954. Urease_beta. 1 hit.
InterProiIPR002019. Urease_beta.
[Graphical view]
PfamiPF00699. Urease_beta. 1 hit.
[Graphical view]
SUPFAMiSSF51278. SSF51278. 1 hit.
TIGRFAMsiTIGR00192. urease_beta. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2JES5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIPGEILTGD DPVEINAGRP VRTVLVRNMG DRPVQVGSHY HFAAANPALD
60 70 80 90 100
FDRASAWGHR LAVPAGTAVR FEPGVEREIE LVPLAGARVV PGLRPESAGP
110 120
LDAASGTRIA DTATIEDISG FQGEGS
Length:126
Mass (Da):13,178
Last modified:March 7, 2006 - v1
Checksum:iCDFF38AB6A0B6024
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000249 Genomic DNA. Translation: ABD10217.1.
RefSeqiWP_011435286.1. NC_007777.1.

Genome annotation databases

EnsemblBacteriaiABD10217; ABD10217; Francci3_0833.
KEGGifra:Francci3_0833.
PATRICi21924578. VBIFraSp10456_0915.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000249 Genomic DNA. Translation: ABD10217.1.
RefSeqiWP_011435286.1. NC_007777.1.

3D structure databases

ProteinModelPortaliQ2JES5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi106370.Francci3_0833.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABD10217; ABD10217; Francci3_0833.
KEGGifra:Francci3_0833.
PATRICi21924578. VBIFraSp10456_0915.

Phylogenomic databases

eggNOGiENOG4105KI2. Bacteria.
COG0832. LUCA.
HOGENOMiHOG000077770.
KOiK01429.
OMAiREVYGFQ.
OrthoDBiPOG091H08S9.

Enzyme and pathway databases

UniPathwayiUPA00258; UER00370.

Family and domain databases

CDDicd00407. Urease_beta. 1 hit.
Gene3Di2.10.150.10. 1 hit.
HAMAPiMF_01954. Urease_beta. 1 hit.
InterProiIPR002019. Urease_beta.
[Graphical view]
PfamiPF00699. Urease_beta. 1 hit.
[Graphical view]
SUPFAMiSSF51278. SSF51278. 1 hit.
TIGRFAMsiTIGR00192. urease_beta. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiURE2_FRASC
AccessioniPrimary (citable) accession number: Q2JES5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 13, 2006
Last sequence update: March 7, 2006
Last modified: November 2, 2016
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.