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Q2JDB8 (Q2JDB8_FRASC) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Malto-oligosyltrehalose trehalohydrolase PIRNR PIRNR006337
Short name=MTHase PIRNR PIRNR006337
EC=3.2.1.141 PIRNR PIRNR006337
Alternative name(s):
4-alpha-D-((1->4)-alpha-D-glucano)trehalose trehalohydrolase PIRNR PIRNR006337
Maltooligosyl trehalose trehalohydrolase PIRNR PIRNR006337
Gene names
Ordered Locus Names:Francci3_1347
OrganismFrankia sp. (strain CcI3) [Complete proteome] [HAMAP] EMBL ABD10724.1
Taxonomic identifier106370 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Frankineae › Frankiaceae › Frankia

Protein attributes

Sequence length593 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Hydrolysis of (1->4)-alpha-D-glucosidic linkage in 4-alpha-D-((1->4)-alpha-D-glucanosyl)(n) trehalose to yield trehalose and (1->4)-alpha-D-glucan. PIRNR PIRNR006337

Pathway

Glycan biosynthesis; trehalose biosynthesis. PIRNR PIRNR006337

Subcellular location

Cytoplasm By similarity PIRSR PIRSR006337-1.

Sequence similarities

Belongs to the glycosyl hydrolase 13 family. PIRNR PIRNR006337

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2521Nucleophile By similarity PIRSR PIRSR006337-1
Active site2891Proton donor By similarity PIRSR PIRSR006337-1
Site3841Transition state stabilizer By similarity PIRSR PIRSR006337-3

Sequences

Sequence LengthMass (Da)Tools
Q2JDB8 [UniParc].

Last modified March 7, 2006. Version 1.
Checksum: 2750DBB49AC7922B

FASTA59364,651
        10         20         30         40         50         60 
MSTLRLWAPE AKTVSLVVAG SAGDSTHEMT AGKRGWWWVN VPSAKHGTDY AFLLDDGSEE 

        70         80         90        100        110        120 
LPDPRSAWQP GPLGVHGRSR LVDHSTFPWT DGTWRGIALA GSVLYELHVG TFTPEGTFDA 

       130        140        150        160        170        180 
AIGKLDHLVE LGIDAIELLP VNAFPGRHGW GYDGVGLFAV HEPYGGPDGL KRFVDAAHAR 

       190        200        210        220        230        240 
GLGVIMDVVY NHLGPDGNYL GRFGPYFTDR YSTPWGPAVN LDAPGSDEVR TFIIDSALSW 

       250        260        270        280        290        300 
LRDYHCDGLR LDAVHAFQDS RALHLLEEIA EAVHRLGAQL RRPLFAVAES DLNDPKLVAA 

       310        320        330        340        350        360 
PEAGGYGLDG QWCDDIHHAL WATLSGERQG YYGDFGSIST LAHALTSGFV HDGGYSTFRG 

       370        380        390        400        410        420 
RSHGRPIPPT TPAYRFVTFL QNHDQIGNRA AGDRASATLS DGLLRIGAAL LLTSAVTPML 

       430        440        450        460        470        480 
FMGEEWGART PWQYFTDHTA PGLGDAVREG RRAEFAAHGW EPQDVPDPQD PATFQQSKLD 

       490        500        510        520        530        540 
WSEPGREGHS DLLDWHRRLI ALRRRLPALT DPAWSSVACT FDEEARWLVV RRGDVAIVVN 

       550        560        570        580        590 
LAAERQAVPL DGVPFDAPAA SAHGFTYMPG RVELDGESVV IIRLLPPVEP TAG

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000249 Genomic DNA. Translation: ABD10724.1.
RefSeqYP_480453.1. NC_007777.1.

3D structure databases

ProteinModelPortalQ2JDB8.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ2JDB8.

Protein family/group databases

CAZyCBM48. Carbohydrate-Binding Module Family 48.
GH13. Glycoside Hydrolase Family 13.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3906560.
GenomeReviewsGene locus Francci3_1347 in contig CP000249_GR.
KEGGfra:Francci3_1347.
PATRIC21925678. VBIFraSp10456_1458.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0296.
HOGENOMHBG367595.
OMAEGFVYQG.
PhylomeDBQ2JDB8.
ProtClustDBCLSK948123.

Family and domain databases

InterProIPR015902. Alpha_amylase.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_subgr_catalytic.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR022567. Maltooligo_trehalose_bac_C.
IPR012768. Trehalose_TreZ.
[Graphical view]
Gene3DG3DSA:3.20.20.80. Glyco_hydro_cat. 2 hits.
G3DSA:2.60.40.10. Ig-like_fold. 1 hit.
KOK01236.
PANTHERPTHR10357. Alpha_amylase. 1 hit.
PTHR10357:SF21. PTHR10357:SF21. 1 hit.
PfamPF00128. Alpha-amylase. 1 hit.
PF02922. CBM_48. 1 hit.
PF11941. DUF3459. 1 hit.
[Graphical view]
PIRSFPIRSF006337. Trehalose_TreZ. 1 hit.
SUPFAMSSF51445. Glyco_hydro_cat. 1 hit.
SSF81296. Ig_E-set. 1 hit.
TIGRFAMsTIGR02402. Trehalose_TreZ. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ2JDB8_FRASC
AccessionPrimary (citable) accession number: Q2JDB8
Entry history
Integrated into UniProtKB/TrEMBL: March 7, 2006
Last sequence update: March 7, 2006
Last modified: December 14, 2011
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info