Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q2JCH8 (PGK_FRASC) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:pgk
Ordered Locus Names:Francci3_1638
OrganismFrankia sp. (strain CcI3) [Complete proteome] [HAMAP]
Taxonomic identifier106370 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesFrankineaeFrankiaceaeFrankia

Protein attributes

Sequence length400 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 400400Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_1000192831

Regions

Nucleotide binding356 – 3594ATP By similarity
Region19 – 213Substrate binding By similarity
Region61 – 644Substrate binding By similarity

Sites

Binding site381Substrate By similarity
Binding site1241Substrate By similarity
Binding site1611Substrate By similarity
Binding site2111ATP By similarity
Binding site2991ATP; via carbonyl oxygen By similarity
Binding site3301ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q2JCH8 [UniParc].

Last modified March 7, 2006. Version 1.
Checksum: E4B3ECCF60800422

FASTA40040,900
        10         20         30         40         50         60 
MRTIDDLQVA GHRVLVRSDL NVPLDRSGDT PRITDDGRVR ASVPTISALL DRGARVVVSS 

        70         80         90        100        110        120 
HLGRPKGEPD PKYSLEPVAG RLAELLGRPV AFAGDGSGDI AGAHAREVVA GLGDGEVALL 

       130        140        150        160        170        180 
ENLRFAAGET SKDAAIRAAF ADELSALAEF YVGDAFGAVH RAHASVADVP KRLPHAAGRL 

       190        200        210        220        230        240 
VLTELEVLRR LSSDPARPYS VVLGGSKVSD KLGVIRALLP KVDALLVGGG MCFTFLAALG 

       250        260        270        280        290        300 
HGVGGSLLET EMIETCKELL AEGGERIVLP TDVVVADRFA ADADTAVVAA DAIPAGWLGL 

       310        320        330        340        350        360 
DIGPASTELF AARLAGAATV FWNGPMGVFE LAPFAAGTRG VAEAVAAGKG FSVVGGGDSA 

       370        380        390        400 
AAVRTLGIPE DAFSHISTGG GASLEYLEGK TLPGLAALDV 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000249 Genomic DNA. Translation: ABD11014.1.
RefSeqYP_480743.1. NC_007777.1.

3D structure databases

ProteinModelPortalQ2JCH8.
SMRQ2JCH8. Positions 1-399.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING106370.Francci3_1638.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABD11014; ABD11014; Francci3_1638.
GeneID3905917.
KEGGfra:Francci3_1638.
PATRIC21926308. VBIFraSp10456_1767.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0126.
HOGENOMHOG000227108.
KOK00927.
OMADMIFDIG.
OrthoDBEOG64N9Z0.
ProtClustDBPRK00073.

Enzyme and pathway databases

BioCycFSP106370:GI1F-1670-MONOMER.
UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
PROSITEPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGK_FRASC
AccessionPrimary (citable) accession number: Q2JCH8
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: March 7, 2006
Last modified: February 19, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways