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Protein

Sec-independent protein translocase protein TatC

Gene

tatC

Organism
Frankia sp. (strain CcI3)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein transport, Translocation, Transport

Enzyme and pathway databases

BioCyciFSP106370:GI1F-2640-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Sec-independent protein translocase protein TatCUniRule annotation
Gene namesi
Name:tatCUniRule annotation
Ordered Locus Names:Francci3_2606
OrganismiFrankia sp. (strain CcI3)
Taxonomic identifieri106370 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaFrankialesFrankiaceaeFrankia
Proteomesi
  • UP000001937 Componenti: Chromosome

Subcellular locationi

  • Cell membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei42 – 6221HelicalUniRule annotationAdd
BLAST
Transmembranei107 – 12721HelicalUniRule annotationAdd
BLAST
Transmembranei139 – 15921HelicalUniRule annotationAdd
BLAST
Transmembranei160 – 18021HelicalUniRule annotationAdd
BLAST
Transmembranei194 – 21421HelicalUniRule annotationAdd
BLAST
Transmembranei225 – 24521HelicalUniRule annotationAdd
BLAST
Transmembranei246 – 26621HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 364364Sec-independent protein translocase protein TatCPRO_0000412865Add
BLAST

Interactioni

Subunit structurei

The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.UniRule annotation

Protein-protein interaction databases

STRINGi106370.Francci3_2606.

Family & Domainsi

Sequence similaritiesi

Belongs to the TatC family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105DCX. Bacteria.
COG0805. LUCA.
HOGENOMiHOG000245380.
KOiK03118.
OMAiTMIATQV.
OrthoDBiPOG091H02DA.

Family and domain databases

HAMAPiMF_00902. TatC. 1 hit.
InterProiIPR002033. TatC.
[Graphical view]
PANTHERiPTHR30371:SF0. PTHR30371:SF0. 1 hit.
PfamiPF00902. TatC. 1 hit.
[Graphical view]
PRINTSiPR01840. TATCFAMILY.
TIGRFAMsiTIGR00945. tatC. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2J9S4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPGLPTPRRL VASVNYRRTR TVEDSRMPLT EHLRELRNRV AIALLAFAIA
60 70 80 90 100
GVVCFIFEPR IFDWLKAPYC DLPASKRFSP DGLAANDCTL YFFGILDAFT
110 120 130 140 150
IRLKISMIAA VVVSSPVWLY QLWSFITPGL HRHERRWSLT FVGVSLVLFA
160 170 180 190 200
TGAVFAYLTL STGLGLLLGF GGNGLVSVLD GNRYLSYVQA MLLIFGLSFE
210 220 230 240 250
VPLLVMMLNL AGIVSTAKLR SWRRPEIFLV FVFAAVVTPS QDPFTMLALG
260 270 280 290 300
LPMVLLYEVA LIIGWLNDRR VARRGDTSPY ADLDDDETSP LDFDDAPPRP
310 320 330 340 350
AASAGPAATA TSPGTANPPG TANPPGTANP VGTANPVGTG SSTPVGAGTA
360
PVSPSTDVTH GDIT
Length:364
Mass (Da):39,153
Last modified:March 7, 2006 - v1
Checksum:i167A6AD20CB0F52F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000249 Genomic DNA. Translation: ABD11968.1.
RefSeqiWP_011437003.1. NC_007777.1.

Genome annotation databases

EnsemblBacteriaiABD11968; ABD11968; Francci3_2606.
KEGGifra:Francci3_2606.
PATRICi21928444. VBIFraSp10456_2836.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000249 Genomic DNA. Translation: ABD11968.1.
RefSeqiWP_011437003.1. NC_007777.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi106370.Francci3_2606.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABD11968; ABD11968; Francci3_2606.
KEGGifra:Francci3_2606.
PATRICi21928444. VBIFraSp10456_2836.

Phylogenomic databases

eggNOGiENOG4105DCX. Bacteria.
COG0805. LUCA.
HOGENOMiHOG000245380.
KOiK03118.
OMAiTMIATQV.
OrthoDBiPOG091H02DA.

Enzyme and pathway databases

BioCyciFSP106370:GI1F-2640-MONOMER.

Family and domain databases

HAMAPiMF_00902. TatC. 1 hit.
InterProiIPR002033. TatC.
[Graphical view]
PANTHERiPTHR30371:SF0. PTHR30371:SF0. 1 hit.
PfamiPF00902. TatC. 1 hit.
[Graphical view]
PRINTSiPR01840. TATCFAMILY.
TIGRFAMsiTIGR00945. tatC. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiTATC_FRASC
AccessioniPrimary (citable) accession number: Q2J9S4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 21, 2011
Last sequence update: March 7, 2006
Last modified: September 7, 2016
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.