ID   Q2J8T2_FRACC            Unreviewed;      1406 AA.
AC   Q2J8T2;
DT   07-MAR-2006, integrated into UniProtKB/TrEMBL.
DT   07-MAR-2006, sequence version 1.
DT   27-MAR-2024, entry version 105.
DE   SubName: Full=Serine/threonine protein kinase {ECO:0000313|EMBL:ABD12310.1};
GN   OrderedLocusNames=Francci3_2952 {ECO:0000313|EMBL:ABD12310.1};
OS   Frankia casuarinae (strain DSM 45818 / CECT 9043 / HFP020203 / CcI3).
OC   Bacteria; Actinomycetota; Actinomycetes; Frankiales; Frankiaceae; Frankia.
OX   NCBI_TaxID=106370 {ECO:0000313|EMBL:ABD12310.1, ECO:0000313|Proteomes:UP000001937};
RN   [1] {ECO:0000313|EMBL:ABD12310.1, ECO:0000313|Proteomes:UP000001937}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45818 / CECT 9043 / CcI3
RC   {ECO:0000313|Proteomes:UP000001937};
RX   PubMed=17151343; DOI=10.1101/gr.5798407;
RA   Normand P., Lapierre P., Tisa L.S., Gogarten J.P., Alloisio N.,
RA   Bagnarol E., Bassi C.A., Berry A.M., Bickhart D.M., Choisne N., Couloux A.,
RA   Cournoyer B., Cruveiller S., Daubin V., Demange N., Francino M.P.,
RA   Goltsman E., Huang Y., Kopp O.R., Labarre L., Lapidus A., Lavire C.,
RA   Marechal J., Martinez M., Mastronunzio J.E., Mullin B.C., Niemann J.,
RA   Pujic P., Rawnsley T., Rouy Z., Schenowitz C., Sellstedt A., Tavares F.,
RA   Tomkins J.P., Vallenet D., Valverde C., Wall L.G., Wang Y., Medigue C.,
RA   Benson D.R.;
RT   "Genome characteristics of facultatively symbiotic Frankia sp. strains
RT   reflect host range and host plant biogeography.";
RL   Genome Res. 17:7-15(2007).
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DR   EMBL; CP000249; ABD12310.1; -; Genomic_DNA.
DR   RefSeq; WP_011437338.1; NZ_JENI01000045.1.
DR   STRING; 106370.Francci3_2952; -.
DR   KEGG; fra:Francci3_2952; -.
DR   eggNOG; COG0515; Bacteria.
DR   HOGENOM; CLU_005315_0_0_11; -.
DR   PhylomeDB; Q2J8T2; -.
DR   Proteomes; UP000001937; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 2.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR011528; NERD.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR017441; Protein_kinase_ATP_BS.
DR   NCBIfam; NF033442; BREX_PglW; 1.
DR   PANTHER; PTHR24349; SERINE/THREONINE-PROTEIN KINASE; 1.
DR   Pfam; PF08378; NERD; 1.
DR   Pfam; PF00069; Pkinase; 2.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 2.
DR   PROSITE; PS50965; NERD; 1.
DR   PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 2.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW   Kinase {ECO:0000313|EMBL:ABD12310.1};
KW   Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001937};
KW   Serine/threonine-protein kinase {ECO:0000313|EMBL:ABD12310.1};
KW   Transferase {ECO:0000313|EMBL:ABD12310.1}.
FT   DOMAIN          12..126
FT                   /note="NERD"
FT                   /evidence="ECO:0000259|PROSITE:PS50965"
FT   DOMAIN          196..478
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
FT   DOMAIN          508..765
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
FT   REGION          354..373
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          976..1007
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        354..372
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        977..993
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         535
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ   SEQUENCE   1406 AA;  153280 MW;  E060AA103DEE8997 CRC64;
     MDDERWTQCT PSEYAWERAA LSYLKAQLPT GDPYRAWANA EFLGSDGSVN EVDLLLVLPA
     GIVVLEIKSW SGVLVGDAGT WRQSHRAPVD NPVIGANRKA RKLKSLLVSR PAMRGRRVPW
     VEGAVFLSDA RLEIRLVPEG RAHVFGRHDQ TQLPSFLDFA RQPGRVDGEL SNALARAVDQ
     AGIRPSQRAR TVGSLRLELP AFQEGVGWQD FLARNQRFPD DRPRRVRIYL ASGVESVHQR
     DQLVRAAERE YLALRGIDYP GIAAPIDFVE HDLGPALVFP HDPELIRLDH FLQEHERELS
     FDDRLALLRV LAETMAYAHR RVLTHRGLSP RCVWVRRRSD RFALQITDWQ TASRGSESTS
     GIPSTTGPAT STGGYVELAD DAAAAYFAPE WSWGTAKGVT LDVFGVGAIA YRIFTGKPPA
     ASSGELSRRL SEHNRLLLAE QVDAVSEELN KLVARATEAD PEQRTRDMAA FLLDLDLVRE
     RLAAIAEEAP VVVDPLEAEA GAELEGGFSV LGRLGRGSTA LALLVERDGG RAVLKVSLDR
     DRDPRLVAEA ETLRTLSEHP GVVQLLSDGV IDVGPRRALL ITSAGERTLA QELRERGRLQ
     PEWLQGWGDD LLEIVQHLQR AGLAHRDIKP DNLGVAERGG RGKKRQLVLF DFSLAKEPLE
     AIEAGTRPYL DPFLGRGERR RWDQAAERYA AAVTLYEMAT ARRPEYGTHG GHPSFVDADV
     AIEPELFDRS YATGLTEFFR RALHRDVRQR FDTAEDMRRA WNAILAEPAS VVPQPPSARI
     SRDTPIGAAG LSRPVLSVFE RLSIDTVGGA LDLSPAQVVW LPGIGTKTRQ QLRADLDRLA
     GQVTSSPAER PTEPTLLDRV AAGLIPRATD RAVAEALLGL GEQGGNAWTS VRDAAKALDR
     EQRTVRQAVA RFERHWLALD GMRELRDTIV KVVESVGGVA SARHCAAALL DFQGSTVEEP
     LRSRLAEAVV RAAIDAELAD DSPRDDTTHD TTHDASGGSE MGGDPRLVYS REPNGILVAA
     GPARAGDGPS TADRLDWASR LGGAADDLAG ADPLPAPARV IETLRAVRAP GDTDPSLIFP
     ERLLDVAMIA SENAAVTPRL EVYPRGLDAG RALRLAAGAL YGRTELTPEQ VAERIIVRFP
     HAGALPGRPE LDALLDAAGV PLCWDDEKKR YVTRRIEVTG LTSLVTSRGT RPRWSTGAGA
     AWTTMGWRRV SDEVLAADDR LTRSLVDGGW LVLSVPPRRL ARAERCLAAQ DVTVVDAEQA
     LLAGMREFCA QHRVQWSIVL AADAADRSSR DWANLSRVAQ AGLAGVRASI EAAGPAVLIT
     NAGVVARYDP ALVVLDELRA SVRMTTETSP VRTVWLLVPW ADVDKQPLLD GGAPVPQFGN
     QGLALSEEWI VRHESRLADG AEGGAA
//