Q2J6H0 (Q2J6H0_FRASC) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
3-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210
EC=2.5.1.19 HAMAP MF_00210

Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase HAMAP MF_00210

Gene names

Name:	aroA HAMAP MF_00210
Ordered Locus Names:	Francci3_3771

Organism

Frankia sp. (strain CcI3) [Complete proteome] [HAMAP] EMBL ABD13122.1

Taxonomic identifier

106370 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Frankineae › Frankiaceae › Frankia

Protein attributes

Sequence length	446 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210
Subunit structure	Monomer By similarity. HAMAP MF_00210
Subcellular location	Cytoplasm By similarity HAMAP MF_00210.
Sequence similarities	Belongs to the EPSP synthase family. HAMAP MF_00210

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis HAMAP MF_00210
Cellular component	Cytoplasm HAMAP MF_00210
Molecular function	Transferase HAMAP MF_00210 EMBL ABD13122.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3-phosphoshikimate 1-carboxyvinyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q2J6H0 [UniParc]. Last modified March 7, 2006. Version 1. Checksum: 4D60ED303246CBA6	FASTA	446	46,292
	10 20 30 40 50 60 MVSILTGSEA TGTQSDPWPA PLARQPVEAV VAVPGSKSGT NRALVLAALA NGTSRLRGAL 70 80 90 100 110 120 RSRDTLLMAG VLRTLGIEVS TEGPDWVVHG HPTPSAAPTA RAECGNAGTV ARFTPALATL 130 140 150 160 170 180 TRGDVVFDGD ARMRERPLTP LLGALRELGA EIDGDRMPFT VHGRGRLRGG EVIVDASHSS 190 200 210 220 230 240 QLVSGLLLAS PHYDTGVTVV HRGSRLPSAP YLDMTVADLR AAGATVEVDA VCSPAAGPVA 250 260 270 280 290 300 DTRRWRVEPG RPTAADRTIE PDMNSAAAFL AAAVATGGRV MISDWPESTE QPGRLLPDLL 310 320 330 340 350 360 VAMGGTARRT SAGLEITGAG AVHGIDVDLS DFGEAAPILT ALAVLADSPS RLRGIAHLRL 370 380 390 400 410 420 QETDRLAALA LELGRLGARI TVADDGLAIS PAPLHGARLD PHADHRLAMA YAVVGLVVPG 430 440 IVIDDIATTG KTVPDFPEMW TAMLDQ

References

[1]

"Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography." Normand P., Lapierre P., Tisa L.S., Gogarten J.P., Alloisio N., Bagnarol E., Bassi C.A., Berry A.M., Bickhart D.M., Choisne N., Couloux A., Cournoyer B., Cruveiller S., Daubin V., Demange N., Francino M.P., Goltsman E., Huang Y. , Kopp O.R., Labarre L., Lapidus A., Lavire C., Marechal J., Martinez M., Mastronunzio J.E., Mullin B.C., Niemann J., Pujic P., Rawnsley T., Rouy Z., Schenowitz C., Sellstedt A., Tavares F., Tomkins J.P., Vallenet D., Valverde C., Wall L.G., Wang Y., Medigue C., Benson D.R. Genome Res. 17:7-15(2007) [PubMed: 17151343] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000249 Genomic DNA. Translation: ABD13122.1.
RefSeq	YP_482851.1. NC_007777.1.
3D structure databases
ProteinModelPortal	Q2J6H0.
ModBase	Search...
Protein-protein interaction databases
STRING	Q2J6H0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3906055.
GenomeReviews	Gene locus Francci3_3771 in contig CP000249_GR.
KEGG	fra:Francci3_3771.
PATRIC	21931004. VBIFraSp10456_4106.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0128.
HOGENOM	HBG646626.
OMA	HRMATAG.
PhylomeDB	Q2J6H0.
ProtClustDB	PRK02427.
Family and domain databases
HAMAP	MF_00210. EPSP_synth. [Tree]
InterPro	IPR001986. Enolpyruvate_Tfrase_dom. IPR006264. EPSP_synthase. IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b. [Graphical view]
Gene3D	G3DSA:3.65.10.10. EPSP_synthase. 2 hits.
KO	K00800.
Pfam	PF00275. EPSP_synthase. 1 hit. [Graphical view]
PIRSF	PIRSF000505. EPSPS. 1 hit.
SUPFAM	SSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMs	TIGR01356. AroA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q2J6H0_FRASC

Accession

Primary (citable) accession number: Q2J6H0

Entry history

Integrated into UniProtKB/TrEMBL:	March 7, 2006
Last sequence update:	March 7, 2006
Last modified:	December 14, 2011
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)