Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase 2

Gene

mshB2

Organism
Frankia sp. (strain CcI3)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.UniRule annotation

Catalytic activityi

1-O-(2-acetamido-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol + H2O = 1-O-(2-amino-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol + acetate.UniRule annotation

Cofactori

Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi25 – 251ZincUniRule annotation
Metal bindingi28 – 281ZincUniRule annotation
Metal bindingi161 – 1611ZincUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

BioCyciFSP106370:GI1F-3915-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase 2UniRule annotation (EC:3.5.1.103UniRule annotation)
Short name:
GlcNAc-Ins deacetylase 2UniRule annotation
Alternative name(s):
N-acetyl-1-D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase 2
Gene namesi
Name:mshB2UniRule annotation
Ordered Locus Names:Francci3_3864
OrganismiFrankia sp. (strain CcI3)
Taxonomic identifieri106370 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaFrankialesFrankiaceaeFrankia
Proteomesi
  • UP000001937 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 3143141D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase 2PRO_0000400186Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi106370.Francci3_3864.

Structurei

3D structure databases

ProteinModelPortaliQ2J678.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MshB deacetylase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108KZ5. Bacteria.
COG2120. LUCA.
HOGENOMiHOG000241173.
KOiK15525.
OMAiCAGDEAD.
OrthoDBiEOG6NSGK1.

Family and domain databases

Gene3Di3.40.50.10320. 1 hit.
HAMAPiMF_01696. MshB.
InterProiIPR003737. GlcNAc_PI_deacetylase-related.
IPR024078. LmbE-like_dom.
IPR017810. Mycothiol_biosynthesis_MshB.
[Graphical view]
PANTHERiPTHR12993. PTHR12993. 1 hit.
PfamiPF02585. PIG-L. 1 hit.
[Graphical view]
SUPFAMiSSF102588. SSF102588. 1 hit.
TIGRFAMsiTIGR03445. mycothiol_MshB. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2J678-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTATPSSPS TAPLPTRRAM FVHAHPDDEV ISTGIALASY AASPDTHVTL
60 70 80 90 100
VTCTLGEEGE VLVPELIHLR ADRGDQLGGY RIGELAGACA ALGITDQRFL
110 120 130 140 150
GGPGRWRDSG MIGTPANDHP RCLWRADLDE AAAELVRIVR EVRPQVLVSY
160 170 180 190 200
DARGGYGHPD HIRAHELTRR AFTDAADPSF APQAGSVWQV AKRYETALAR
210 220 230 240 250
SSAVAGFEYF RDSAAESNPF AGLTSVDELG VTLVDDADIT TELSAPHFFE
260 270 280 290 300
AKIAAMRSHR TQMSVDGFFF ALADGIGQRA WSVEHFVLAE GARGPGDGPD
310
GRERDLFAGL VCEP
Length:314
Mass (Da):33,683
Last modified:March 7, 2006 - v1
Checksum:i31FEA7F02FA6A784
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000249 Genomic DNA. Translation: ABD13214.1.

Genome annotation databases

EnsemblBacteriaiABD13214; ABD13214; Francci3_3864.
KEGGifra:Francci3_3864.
PATRICi21931206. VBIFraSp10456_4206.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000249 Genomic DNA. Translation: ABD13214.1.

3D structure databases

ProteinModelPortaliQ2J678.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi106370.Francci3_3864.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABD13214; ABD13214; Francci3_3864.
KEGGifra:Francci3_3864.
PATRICi21931206. VBIFraSp10456_4206.

Phylogenomic databases

eggNOGiENOG4108KZ5. Bacteria.
COG2120. LUCA.
HOGENOMiHOG000241173.
KOiK15525.
OMAiCAGDEAD.
OrthoDBiEOG6NSGK1.

Enzyme and pathway databases

BioCyciFSP106370:GI1F-3915-MONOMER.

Family and domain databases

Gene3Di3.40.50.10320. 1 hit.
HAMAPiMF_01696. MshB.
InterProiIPR003737. GlcNAc_PI_deacetylase-related.
IPR024078. LmbE-like_dom.
IPR017810. Mycothiol_biosynthesis_MshB.
[Graphical view]
PANTHERiPTHR12993. PTHR12993. 1 hit.
PfamiPF02585. PIG-L. 1 hit.
[Graphical view]
SUPFAMiSSF102588. SSF102588. 1 hit.
TIGRFAMsiTIGR03445. mycothiol_MshB. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CcI3.

Entry informationi

Entry nameiMSHB2_FRASC
AccessioniPrimary (citable) accession number: Q2J678
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 2, 2010
Last sequence update: March 7, 2006
Last modified: December 9, 2015
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.