Q2J5C6 (Q2J5C6_FRASC) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
DNA polymerase III, alpha subunit EMBL ABD13516.1
EC=2.7.7.7 EMBL ABD13516.1

Gene names

Ordered Locus Names:

Francci3_4168

Organism

Frankia sp. (strain CcI3) [Complete proteome] [HAMAP] EMBL ABD13516.1

Taxonomic identifier

106370 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Frankineae › Frankiaceae › Frankia

Protein attributes

Sequence length	1249 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). SAAS SAAS004013

Ontologies

Keywords
Biological process	DNA replication SAAS SAAS004013
Cellular component	Cytoplasm SAAS SAAS004013
Molecular function	DNA-directed DNA polymerase SAAS SAAS004013 Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q2J5C6 [UniParc]. Last modified March 7, 2006. Version 1. Checksum: 5F1A635D8EED421F	FASTA	1,249	136,164
	10 20 30 40 50 60 MPTDSFVHLH VHTEYSMLDG AAKTGLLFKE AAKLGMPAVG MTDHGNMFGA YEFYQGAKSA 70 80 90 100 110 120 GVKPIIGIEA YLAPESRHHK RPVLWGERSQ RDVDPAGEGG DVSGGGAYTH MTMLAANAAG 130 140 150 160 170 180 LRNLFRLSSI ASIEGYYRKP RMDHELVSQY SEGIIATTGC PSGEVQTRLR LGQFDKALAA 190 200 210 220 230 240 AATYQEVFGA DNFFLELMDH GLPIERSVRQ GLLDIGDKLG LRPLATNDSH YVTQDQAGSH 250 260 270 280 290 300 EVLLCVGTGK KLDDPTRFKF DGSGYYLKSS EEMRNLWDSE VPGACDSSLL IAERVESYDD 310 320 330 340 350 360 VFKFVDRMPR YPVPAGETQL SWLRKEIDRG LTWRFPAGVP ADVVERVDYE VGVIDKMGFP 370 380 390 400 410 420 AYFLVVADIC KFARDRGIGL GPGRGSATGS MIAYILGITE LNPIEHALIF ERFLNPERIS 430 440 450 460 470 480 PPDIDLDFDE RRRGEVIRYI TEQYGEDRVA QINTFGTIKA KAAIKDSCRV LGYDYALGDK 490 500 510 520 530 540 ISKAMPPDVM GQGIPLAGIF DPNHERYGEA AEVRAQYETD TKVRKVIDTA RGLEGLTRGT 550 560 570 580 590 600 GVHAAGVILC SEPLLDVLPI HRRDNDGAII TGFPFPQCEE MGLLKMDCLG LRNLTVIGDA 610 620 630 640 650 660 IEAVKRNRNV DIDLSTLPLE DAKAFELLAR GDTLGVFQLD GGPMRNLLRL MAPTKFGDIA 670 680 690 700 710 720 AVLALYRPGP MAANSHIEYA DRKNGRKEIL PIHPELAEAL EPILGETYHL VVYQEQVMAI 730 740 750 760 770 780 ARELAGYSLG GADLLRRAMG KKKKEILDKE FARFSAGMKE RGYTDAAVQA LWDVLVPFSG 790 800 810 820 830 840 YGFNKSHTAG YGVVSFWTAY LKANYPAEFM AALLTSVGDD KDKMAVYLAE TRRMGIQVLP 850 860 870 880 890 900 PDVNESDLRF GAVGDSIRFG LGAVRNVGEN VVASIAAARR RKGAYESFAD FLQKVDIGVC 910 920 930 940 950 960 NKRTIDSLIK AGAFDSLGHH RRVLVNVHEN AIDAVIITKR AEAIGQFDLF GDGGAGEEEE 970 980 990 1000 1010 1020 SPGLGLDLDL SGPEWPKKEL LAQERDMLGL YVSSHPLEGA ERALDRHRDT RIVDLAEAND 1030 1040 1050 1060 1070 1080 GTTVQIAGII SKIDRRINKN TAKAWAIVTV EDLDASVEVL FFPQSYEVHS YALATDAVIS 1090 1100 1110 1120 1130 1140 VRGRINEREG SVSLFAQDLT VVDVATHVNG PPVVITLPSH KITPPLVDDL KLVLTTHPGT 1150 1160 1170 1180 1190 1200 TPVHLRLEGP QNTHLLLLEL QVQASSSLLG DLKALLGALL HWAEAGRGGA VSGGRSDGQG 1210 1220 1230 1240 EFGEGSRQPV PEVGIDAQFV VAAADVLHER VPGADDLCGA EAFQAAHRP

References

[1]

"Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography." Normand P., Lapierre P., Tisa L.S., Gogarten J.P., Alloisio N., Bagnarol E., Bassi C.A., Berry A.M., Bickhart D.M., Choisne N., Couloux A., Cournoyer B., Cruveiller S., Daubin V., Demange N., Francino M.P., Goltsman E., Huang Y. , Kopp O.R., Labarre L., Lapidus A., Lavire C., Marechal J., Martinez M., Mastronunzio J.E., Mullin B.C., Niemann J., Pujic P., Rawnsley T., Rouy Z., Schenowitz C., Sellstedt A., Tavares F., Tomkins J.P., Vallenet D., Valverde C., Wall L.G., Wang Y., Medigue C., Benson D.R. Genome Res. 17:7-15(2007) [PubMed: 17151343] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000249 Genomic DNA. Translation: ABD13516.1.
RefSeq	YP_483245.1. NC_007777.1.
3D structure databases
ProteinModelPortal	Q2J5C6.
ModBase	Search...
Protein-protein interaction databases
STRING	Q2J5C6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3907133.
GenomeReviews	Gene locus Francci3_4168 in contig CP000249_GR.
KEGG	fra:Francci3_4168.
PATRIC	21931852. VBIFraSp10456_4525.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0587.
HOGENOM	HBG734490.
OMA	RVLQMPY.
PhylomeDB	Q2J5C6.
ProtClustDB	PRK05673.
Family and domain databases
InterPro	IPR011708. DNA_pol3_alpha. IPR004365. NA-bd_OB_tRNA-helicase. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR016195. Pol/histidinol_Pase-like. IPR004805. PolC_alpha. [Graphical view]
KO	K02337.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
SUPFAM	SSF89550. PHP-like. 1 hit.
TIGRFAMs	TIGR00594. Polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q2J5C6_FRASC

Accession

Primary (citable) accession number: Q2J5C6

Entry history

Integrated into UniProtKB/TrEMBL:	March 7, 2006
Last sequence update:	March 7, 2006
Last modified:	December 14, 2011
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)