Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Catalase-peroxidase

Gene

katG

Organism
Rhodopseudomonas palustris (strain HaA2)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.UniRule annotation

Catalytic activityi

Donor + H2O2 = oxidized donor + 2 H2O.UniRule annotation
2 H2O2 = O2 + 2 H2O.UniRule annotation

Cofactori

heme bUniRule annotationNote: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei94 – 941Transition state stabilizerUniRule annotation
Active sitei98 – 981Proton acceptorUniRule annotation
Metal bindingi260 – 2601Iron (heme axial ligand)UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase, Peroxidase

Keywords - Biological processi

Hydrogen peroxide

Keywords - Ligandi

Heme, Iron, Metal-binding

Enzyme and pathway databases

BioCyciRPAL316058:GHF1-619-MONOMER.

Protein family/group databases

PeroxiBasei3652. RpCP01_HaA2.

Names & Taxonomyi

Protein namesi
Recommended name:
Catalase-peroxidaseUniRule annotation (EC:1.11.1.21UniRule annotation)
Short name:
CPUniRule annotation
Alternative name(s):
Peroxidase/catalaseUniRule annotation
Gene namesi
Name:katGUniRule annotation
Ordered Locus Names:RPB_0610
OrganismiRhodopseudomonas palustris (strain HaA2)
Taxonomic identifieri316058 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeRhodopseudomonas
Proteomesi
  • UP000008809 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 732732Catalase-peroxidasePRO_0000354896Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Cross-linki97 ↔ 219Tryptophyl-tyrosyl-methioninium (Trp-Tyr) (with M-245)UniRule annotation
Cross-linki219 ↔ 245Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with W-97)UniRule annotation

Post-translational modificationi

The covalent Trp-Tyr-Met adduct is important for the catalase, but not the peroxidase activity of the enzyme.UniRule annotation

Interactioni

Subunit structurei

Homodimer or homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi316058.RPB_0610.

Family & Domainsi

Sequence similaritiesi

Belongs to the peroxidase family. Peroxidase/catalase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C1X. Bacteria.
COG0376. LUCA.
HOGENOMiHOG000218110.
KOiK03782.
OMAiYGATTMG.
OrthoDBiPOG091H05R1.

Family and domain databases

HAMAPiMF_01961. Catal_peroxid. 1 hit.
InterProiIPR000763. Catalase_peroxidase.
IPR010255. Haem_peroxidase.
IPR002016. Haem_peroxidase_pln/fun/bac.
IPR019794. Peroxidases_AS.
IPR019793. Peroxidases_heam-ligand_BS.
[Graphical view]
PfamiPF00141. peroxidase. 2 hits.
[Graphical view]
PRINTSiPR00460. BPEROXIDASE.
PR00458. PEROXIDASE.
SUPFAMiSSF48113. SSF48113. 2 hits.
TIGRFAMsiTIGR00198. cat_per_HPI. 1 hit.
PROSITEiPS00435. PEROXIDASE_1. 1 hit.
PS00436. PEROXIDASE_2. 1 hit.
PS50873. PEROXIDASE_4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2J2I9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDAKTDDKDG GKCPFPHGGG RGRRNSDWWP EHLDISLLHR NSTLSDPMGK
60 70 80 90 100
GFDYAREFES LDLDAVIKDL HALMTDSQDW WPADFGHYGG LMVRMAWHSA
110 120 130 140 150
GTYRTTDGRG GAGAGQQRFA PLNSWPDNAN LDKARRLLWP IKQKYGNKIS
160 170 180 190 200
WADLYVLTGN VALESMGFKT FGFAGGRADT WEPEELFWGP EGSWLGDERY
210 220 230 240 250
SGERELSDPL GAVQMGLIYV NPEGPNGNPD PVAAAKDIRE TFARMAMNDE
260 270 280 290 300
ETVALIAGGH TFGKTHGAGD PSLIGAEPEG GALEDQGLGW KSSFGTGFGA
310 320 330 340 350
DAITGGPEVI WTQTPTQWSN HFFENLFGFE WELDKSPAGA KQWKAKGAEA
360 370 380 390 400
NIPDPFDPTK KRLPTMLTTD LSLRFDPAYE KISRRFLENP DQFADAFARA
410 420 430 440 450
WFKLTHRDMG PKVRYRGKLV PKEDLIWQDP IPPVDHELVG DKDIAALKAK
460 470 480 490 500
ILGSGLSVSQ LVSAAFASAS TYRHSDKRGG ANGARIRFAP QKDWEVNQPS
510 520 530 540 550
DLAQVLSKLE AIQKEFNGAQ TDGKKVSLAD LIVLGGCAAV EKAAKDAGTD
560 570 580 590 600
IQVPFTPGRM DALEEQTDAD SFKVLEPRAD GFRNFIGKRK QYMSPEESLV
610 620 630 640 650
DRAQLLNLTA PEMTALLGGL RVLGGNVGHT THGVFTERPE KLTNDFFVNL
660 670 680 690 700
LDMKTAWSPS ATTEVVYEGR DRKTGELRWT GTRVDLIFGS HSQLRALAEV
710 720 730
YAQSDAQPKF ARDFVAAWTK VMNADRFDIV AK
Length:732
Mass (Da):80,663
Last modified:March 7, 2006 - v1
Checksum:i8C58B74ED4DCC0EB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000250 Genomic DNA. Translation: ABD05321.1.
RefSeqiWP_011439511.1. NC_007778.1.

Genome annotation databases

EnsemblBacteriaiABD05321; ABD05321; RPB_0610.
KEGGirpb:RPB_0610.
PATRICi23295683. VBIRhoPal125544_0642.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000250 Genomic DNA. Translation: ABD05321.1.
RefSeqiWP_011439511.1. NC_007778.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi316058.RPB_0610.

Protein family/group databases

PeroxiBasei3652. RpCP01_HaA2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABD05321; ABD05321; RPB_0610.
KEGGirpb:RPB_0610.
PATRICi23295683. VBIRhoPal125544_0642.

Phylogenomic databases

eggNOGiENOG4105C1X. Bacteria.
COG0376. LUCA.
HOGENOMiHOG000218110.
KOiK03782.
OMAiYGATTMG.
OrthoDBiPOG091H05R1.

Enzyme and pathway databases

BioCyciRPAL316058:GHF1-619-MONOMER.

Family and domain databases

HAMAPiMF_01961. Catal_peroxid. 1 hit.
InterProiIPR000763. Catalase_peroxidase.
IPR010255. Haem_peroxidase.
IPR002016. Haem_peroxidase_pln/fun/bac.
IPR019794. Peroxidases_AS.
IPR019793. Peroxidases_heam-ligand_BS.
[Graphical view]
PfamiPF00141. peroxidase. 2 hits.
[Graphical view]
PRINTSiPR00460. BPEROXIDASE.
PR00458. PEROXIDASE.
SUPFAMiSSF48113. SSF48113. 2 hits.
TIGRFAMsiTIGR00198. cat_per_HPI. 1 hit.
PROSITEiPS00435. PEROXIDASE_1. 1 hit.
PS00436. PEROXIDASE_2. 1 hit.
PS50873. PEROXIDASE_4. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiKATG_RHOP2
AccessioniPrimary (citable) accession number: Q2J2I9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 25, 2008
Last sequence update: March 7, 2006
Last modified: September 7, 2016
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.