Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q2J0J8

- AROE_RHOP2

UniProt

Q2J0J8 - AROE_RHOP2

Protein

Shikimate dehydrogenase

Gene

aroE

Organism
Rhodopseudomonas palustris (strain HaA2)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 68 (01 Oct 2014)
      Sequence version 1 (07 Mar 2006)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    Shikimate + NADP+ = 3-dehydroshikimate + NADPH.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei71 – 711Proton acceptorUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi131 – 1355NADPUniRule annotation

    GO - Molecular functioni

    1. NADP binding Source: InterPro
    2. shikimate 3-dehydrogenase (NADP+) activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. aromatic amino acid family biosynthetic process Source: UniProtKB-HAMAP
    2. chorismate biosynthetic process Source: UniProtKB-UniPathway
    3. shikimate metabolic process Source: InterPro

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Amino-acid biosynthesis, Aromatic amino acid biosynthesis

    Keywords - Ligandi

    NADP

    Enzyme and pathway databases

    BioCyciRPAL316058:GHF1-1320-MONOMER.
    UniPathwayiUPA00053; UER00087.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Shikimate dehydrogenaseUniRule annotation (EC:1.1.1.25UniRule annotation)
    Gene namesi
    Name:aroEUniRule annotation
    Ordered Locus Names:RPB_1302
    OrganismiRhodopseudomonas palustris (strain HaA2)
    Taxonomic identifieri316058 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeRhodopseudomonas
    ProteomesiUP000008809: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 280280Shikimate dehydrogenasePRO_1000021321Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi316058.RPB_1302.

    Structurei

    3D structure databases

    ProteinModelPortaliQ2J0J8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the shikimate dehydrogenase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0169.
    HOGENOMiHOG000237875.
    KOiK00014.
    OMAiTTSVGMH.
    OrthoDBiEOG64R67G.

    Family and domain databases

    Gene3Di3.40.50.720. 1 hit.
    HAMAPiMF_00222. Shikimate_DH_AroE.
    InterProiIPR016040. NAD(P)-bd_dom.
    IPR011342. Shikimate_DH.
    IPR013708. Shikimate_DH-bd_N.
    IPR022893. Shikimate_quinate_DH.
    IPR006151. Shikm_DH/Glu-tRNA_Rdtase.
    [Graphical view]
    PfamiPF01488. Shikimate_DH. 1 hit.
    PF08501. Shikimate_dh_N. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00507. aroE. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q2J0J8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MHPGDGHTAA CLIGWPAAHS RSPLIHHYWL RTLGIPGGYS IESVPPEGFA    50
    EFVLNLRAHG YSGANVTIPH KERALQLTQP DDRARAVGAA NTLYYDGDVL 100
    RSTNTDVEGF IANLDASAPG WDRTPHAVVL GAGGSARAVL FGLLERGIER 150
    IALANRSLER AQALADLFGE RVVPIAWTDA PAALPGAGLL VNTTSLGMKG 200
    QPSLDLDLEP LPSDATVADL VYVPLETELL AEARGRGLRT ADGLGMLLHQ 250
    AVRGFELWFG ARPHVTAELR ALVEADLAAK 280
    Length:280
    Mass (Da):29,776
    Last modified:March 7, 2006 - v1
    Checksum:iC34B059DDD174A25
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000250 Genomic DNA. Translation: ABD06012.1.
    RefSeqiYP_484923.1. NC_007778.1.

    Genome annotation databases

    EnsemblBacteriaiABD06012; ABD06012; RPB_1302.
    GeneIDi3908175.
    KEGGirpb:RPB_1302.
    PATRICi23297165. VBIRhoPal125544_1378.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000250 Genomic DNA. Translation: ABD06012.1 .
    RefSeqi YP_484923.1. NC_007778.1.

    3D structure databases

    ProteinModelPortali Q2J0J8.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 316058.RPB_1302.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABD06012 ; ABD06012 ; RPB_1302 .
    GeneIDi 3908175.
    KEGGi rpb:RPB_1302.
    PATRICi 23297165. VBIRhoPal125544_1378.

    Phylogenomic databases

    eggNOGi COG0169.
    HOGENOMi HOG000237875.
    KOi K00014.
    OMAi TTSVGMH.
    OrthoDBi EOG64R67G.

    Enzyme and pathway databases

    UniPathwayi UPA00053 ; UER00087 .
    BioCyci RPAL316058:GHF1-1320-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.720. 1 hit.
    HAMAPi MF_00222. Shikimate_DH_AroE.
    InterProi IPR016040. NAD(P)-bd_dom.
    IPR011342. Shikimate_DH.
    IPR013708. Shikimate_DH-bd_N.
    IPR022893. Shikimate_quinate_DH.
    IPR006151. Shikm_DH/Glu-tRNA_Rdtase.
    [Graphical view ]
    Pfami PF01488. Shikimate_DH. 1 hit.
    PF08501. Shikimate_dh_N. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00507. aroE. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: HaA2.

    Entry informationi

    Entry nameiAROE_RHOP2
    AccessioniPrimary (citable) accession number: Q2J0J8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: March 7, 2006
    Last modified: October 1, 2014
    This is version 68 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3