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Q2J0J8

- AROE_RHOP2

UniProt

Q2J0J8 - AROE_RHOP2

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Protein

Shikimate dehydrogenase

Gene

aroE

Organism
Rhodopseudomonas palustris (strain HaA2)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

Shikimate + NADP+ = 3-dehydroshikimate + NADPH.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei71 – 711Proton acceptorUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi131 – 1355NADPUniRule annotation

GO - Molecular functioni

  1. NADP binding Source: InterPro
  2. shikimate 3-dehydrogenase (NADP+) activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. aromatic amino acid family biosynthetic process Source: UniProtKB-HAMAP
  2. chorismate biosynthetic process Source: UniProtKB-UniPathway
  3. shikimate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis

Keywords - Ligandi

NADP

Enzyme and pathway databases

BioCyciRPAL316058:GHF1-1320-MONOMER.
UniPathwayiUPA00053; UER00087.

Names & Taxonomyi

Protein namesi
Recommended name:
Shikimate dehydrogenaseUniRule annotation (EC:1.1.1.25UniRule annotation)
Gene namesi
Name:aroEUniRule annotation
Ordered Locus Names:RPB_1302
OrganismiRhodopseudomonas palustris (strain HaA2)
Taxonomic identifieri316058 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeRhodopseudomonas
ProteomesiUP000008809: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 280280Shikimate dehydrogenasePRO_1000021321Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi316058.RPB_1302.

Structurei

3D structure databases

ProteinModelPortaliQ2J0J8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the shikimate dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0169.
HOGENOMiHOG000237875.
KOiK00014.
OMAiTTSVGMH.
OrthoDBiEOG64R67G.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
HAMAPiMF_00222. Shikimate_DH_AroE.
InterProiIPR016040. NAD(P)-bd_dom.
IPR011342. Shikimate_DH.
IPR013708. Shikimate_DH-bd_N.
IPR022893. Shikimate_quinate_DH.
IPR006151. Shikm_DH/Glu-tRNA_Rdtase.
[Graphical view]
PfamiPF01488. Shikimate_DH. 1 hit.
PF08501. Shikimate_dh_N. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00507. aroE. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2J0J8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MHPGDGHTAA CLIGWPAAHS RSPLIHHYWL RTLGIPGGYS IESVPPEGFA
60 70 80 90 100
EFVLNLRAHG YSGANVTIPH KERALQLTQP DDRARAVGAA NTLYYDGDVL
110 120 130 140 150
RSTNTDVEGF IANLDASAPG WDRTPHAVVL GAGGSARAVL FGLLERGIER
160 170 180 190 200
IALANRSLER AQALADLFGE RVVPIAWTDA PAALPGAGLL VNTTSLGMKG
210 220 230 240 250
QPSLDLDLEP LPSDATVADL VYVPLETELL AEARGRGLRT ADGLGMLLHQ
260 270 280
AVRGFELWFG ARPHVTAELR ALVEADLAAK
Length:280
Mass (Da):29,776
Last modified:March 7, 2006 - v1
Checksum:iC34B059DDD174A25
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000250 Genomic DNA. Translation: ABD06012.1.
RefSeqiYP_484923.1. NC_007778.1.

Genome annotation databases

EnsemblBacteriaiABD06012; ABD06012; RPB_1302.
GeneIDi3908175.
KEGGirpb:RPB_1302.
PATRICi23297165. VBIRhoPal125544_1378.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000250 Genomic DNA. Translation: ABD06012.1 .
RefSeqi YP_484923.1. NC_007778.1.

3D structure databases

ProteinModelPortali Q2J0J8.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 316058.RPB_1302.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABD06012 ; ABD06012 ; RPB_1302 .
GeneIDi 3908175.
KEGGi rpb:RPB_1302.
PATRICi 23297165. VBIRhoPal125544_1378.

Phylogenomic databases

eggNOGi COG0169.
HOGENOMi HOG000237875.
KOi K00014.
OMAi TTSVGMH.
OrthoDBi EOG64R67G.

Enzyme and pathway databases

UniPathwayi UPA00053 ; UER00087 .
BioCyci RPAL316058:GHF1-1320-MONOMER.

Family and domain databases

Gene3Di 3.40.50.720. 1 hit.
HAMAPi MF_00222. Shikimate_DH_AroE.
InterProi IPR016040. NAD(P)-bd_dom.
IPR011342. Shikimate_DH.
IPR013708. Shikimate_DH-bd_N.
IPR022893. Shikimate_quinate_DH.
IPR006151. Shikm_DH/Glu-tRNA_Rdtase.
[Graphical view ]
Pfami PF01488. Shikimate_DH. 1 hit.
PF08501. Shikimate_dh_N. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00507. aroE. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HaA2.

Entry informationi

Entry nameiAROE_RHOP2
AccessioniPrimary (citable) accession number: Q2J0J8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: March 7, 2006
Last modified: October 1, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3