Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q2J0A5

- MASZ_RHOP2

UniProt

Q2J0A5 - MASZ_RHOP2

Protein

Malate synthase G

Gene

glcB

Organism
Rhodopseudomonas palustris (strain HaA2)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 57 (01 Oct 2014)
      Sequence version 1 (07 Mar 2006)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.UniRule annotation

    Catalytic activityi

    Acetyl-CoA + H2O + glyoxylate = (S)-malate + CoA.UniRule annotation

    Cofactori

    Magnesium.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei117 – 1171Acetyl-CoA; via carbonyl oxygenUniRule annotation
    Binding sitei273 – 2731Acetyl-CoAUniRule annotation
    Binding sitei310 – 3101Acetyl-CoAUniRule annotation
    Active sitei337 – 3371Proton acceptorUniRule annotation
    Binding sitei337 – 3371GlyoxylateUniRule annotation
    Metal bindingi429 – 4291MagnesiumUniRule annotation
    Binding sitei429 – 4291GlyoxylateUniRule annotation
    Metal bindingi457 – 4571MagnesiumUniRule annotation
    Binding sitei538 – 5381Acetyl-CoA; via carbonyl oxygenUniRule annotation
    Active sitei628 – 6281Proton donorUniRule annotation

    GO - Molecular functioni

    1. malate synthase activity Source: UniProtKB-HAMAP
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. glyoxylate cycle Source: UniProtKB-HAMAP
    2. tricarboxylic acid cycle Source: UniProtKB-KW

    Keywords - Molecular functioni

    Transferase

    Keywords - Biological processi

    Glyoxylate bypass, Tricarboxylic acid cycle

    Keywords - Ligandi

    Magnesium, Metal-binding

    Enzyme and pathway databases

    BioCyciRPAL316058:GHF1-1413-MONOMER.
    UniPathwayiUPA00703; UER00720.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Malate synthase GUniRule annotation (EC:2.3.3.9UniRule annotation)
    Gene namesi
    Name:glcBUniRule annotation
    Ordered Locus Names:RPB_1395
    OrganismiRhodopseudomonas palustris (strain HaA2)
    Taxonomic identifieri316058 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeRhodopseudomonas
    ProteomesiUP000008809: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 724724Malate synthase GPRO_1000056923Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei614 – 6141Cysteine sulfenic acid (-SOH)UniRule annotation

    Keywords - PTMi

    Oxidation

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi316058.RPB_1395.

    Structurei

    3D structure databases

    ProteinModelPortaliQ2J0A5.
    SMRiQ2J0A5. Positions 2-717.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni124 – 1252Acetyl-CoA bindingUniRule annotation
    Regioni454 – 4574Glyoxylate bindingUniRule annotation

    Sequence similaritiesi

    Belongs to the malate synthase family. GlcB subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2225.
    HOGENOMiHOG000220740.
    KOiK01638.
    OMAiSQFIENE.
    OrthoDBiEOG6HJ286.

    Family and domain databases

    Gene3Di2.170.170.11. 2 hits.
    HAMAPiMF_00641. Malate_synth_G.
    InterProiIPR011076. Malate_synth-like.
    IPR023310. Malate_synth_G_beta_sub_dom.
    IPR001465. Malate_synthase.
    IPR006253. Malate_synthG.
    [Graphical view]
    PfamiPF01274. Malate_synthase. 1 hit.
    [Graphical view]
    SUPFAMiSSF51645. SSF51645. 1 hit.
    TIGRFAMsiTIGR01345. malate_syn_G. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q2J0A5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNRIDAHGLK IAPVLFDFIA KEAAPKTGVA PDAFWAGLAA IVRDLTPKTV    50
    ALLQHRDGLQ AKIDAWHLAN KGKKQDMAAY TAFLKEIGYL LPEPPTVAVE 100
    TANVDDEIGK LCGPQLVVPL SNARYALNAA NARWGSLYDA FYGTDAIPQE 150
    ASQAKGYDKA RGDKVIAKAK AFLDQAAPLV AGSHSDVTAY SVIAGQLSAK 200
    LKSGNATGLK TPRQFAGYLG DAASPSAVLL VNNGLHIEIK IDRANTIGKD 250
    DAAGVADLVI ESAVSTILDM EDSVAAVDAE DKVLIYRNTL GLMDGTLSAD 300
    FDKGGKTVTR ALNGDRTYTG PDGKDVTLHG RSLLLMRNVG HHMWTDAVLD 350
    SNGDEIPEGF LDAAVSGLLA IHDLKALGKT RNSRTGSVYI VKPKMHGPDE 400
    VALTCELFGR VEQMLGLKEN TLKVGIMDEE RRTTVNLKAC IQNASKRIVF 450
    INTGFLDRTG DEIHTSMEAG PMIRKNEMKA QPWIKAYEDW NVDTGLIDGL 500
    PGHAQIGKGM WAAPDKMADM LTQKIGHPQA GATTAWVPSP TAATLHALHY 550
    HQVDVLARQQ ELKTGGPRAK LEDILTIPVS QSNWAPDDVR QEIDNNCQGI 600
    LGYVVRWIDQ GVGCSKVPDI HDVGLMEDRA TLRISSQHLA NWLHHGVVTK 650
    EQVLESLKRM AAVVDKQNAG DPLYRPMAPD FDGVAFEAAC DLIFKGREQP 700
    NGYTEFILHI RRREAKAAHL QDLT 724
    Length:724
    Mass (Da):78,443
    Last modified:March 7, 2006 - v1
    Checksum:i2D5D28519CD7EE0A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000250 Genomic DNA. Translation: ABD06105.1.
    RefSeqiYP_485016.1. NC_007778.1.

    Genome annotation databases

    EnsemblBacteriaiABD06105; ABD06105; RPB_1395.
    GeneIDi3908345.
    KEGGirpb:RPB_1395.
    PATRICi23297357. VBIRhoPal125544_1474.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000250 Genomic DNA. Translation: ABD06105.1 .
    RefSeqi YP_485016.1. NC_007778.1.

    3D structure databases

    ProteinModelPortali Q2J0A5.
    SMRi Q2J0A5. Positions 2-717.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 316058.RPB_1395.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABD06105 ; ABD06105 ; RPB_1395 .
    GeneIDi 3908345.
    KEGGi rpb:RPB_1395.
    PATRICi 23297357. VBIRhoPal125544_1474.

    Phylogenomic databases

    eggNOGi COG2225.
    HOGENOMi HOG000220740.
    KOi K01638.
    OMAi SQFIENE.
    OrthoDBi EOG6HJ286.

    Enzyme and pathway databases

    UniPathwayi UPA00703 ; UER00720 .
    BioCyci RPAL316058:GHF1-1413-MONOMER.

    Family and domain databases

    Gene3Di 2.170.170.11. 2 hits.
    HAMAPi MF_00641. Malate_synth_G.
    InterProi IPR011076. Malate_synth-like.
    IPR023310. Malate_synth_G_beta_sub_dom.
    IPR001465. Malate_synthase.
    IPR006253. Malate_synthG.
    [Graphical view ]
    Pfami PF01274. Malate_synthase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51645. SSF51645. 1 hit.
    TIGRFAMsi TIGR01345. malate_syn_G. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: HaA2.

    Entry informationi

    Entry nameiMASZ_RHOP2
    AccessioniPrimary (citable) accession number: Q2J0A5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: March 7, 2006
    Last modified: October 1, 2014
    This is version 57 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3