Q2IZZ7 (DADA_RHOP2) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
D-amino acid dehydrogenase small subunit
EC=1.4.99.1

Gene names

Name:	dadA
Ordered Locus Names:	RPB_1503

Organism

Rhodopseudomonas palustris (strain HaA2) [Complete proteome] [HAMAP]

Taxonomic identifier

316058 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Rhodopseudomonas

Protein attributes

Sequence length	425 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Oxidative deamination of D-amino acids By similarity. HAMAP MF_01202
Catalytic activity	A D-amino acid + H2O + acceptor = a 2-oxo acid + NH3 + reduced acceptor. HAMAP MF_01202
Cofactor	FAD By similarity. HAMAP MF_01202
Pathway	Amino-acid degradation; D-alanine degradation; NH(3) and pyruvate from D-alanine: step 1/1. HAMAP MF_01202
Subunit structure	Heterodimer of a small and a large subunit By similarity.
Sequence similarities	Belongs to the DadA oxidoreductase family.

Ontologies

Keywords
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	D-amino-acid dehydrogenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 425	425	D-amino acid dehydrogenase small subunit HAMAP MF_01202		PRO_1000066110
Regions
	Nucleotide binding	3 – 17	15	FAD Potential

Sequences

	Sequence		Length	Mass (Da)
	Q2IZZ7 [UniParc]. Last modified March 7, 2006. Version 1. Checksum: BF8AE83D241135A4	FASTA	425	45,886
	10 20 30 40 50 60 MKVLVMGAGV IGVTTAYYLA KAGFEVTVID RQPGPGLETS FANAGEVSPG YSSPWAGPGV 70 80 90 100 110 120 PRKAIQWILD RHGPLVVRPQ IDPAMWRWVV QMLRNCTASR YALNKSRMVG IAEYSRDCLR 130 140 150 160 170 180 ALRADIGITY DERSQGTLQL FRKQSQLDAI GGDVEILRQY NVPFEVLDRA GCIRAEPGLA 190 200 210 220 230 240 AVQNSFVGGL RLVDDETGDC HLFTQRLEAA AAALGVNFVY ETTIRSIDAQ GGAVAGVTTD 250 260 270 280 290 300 KGRFVADRYV MALGSFSPLL LRPLGIDIPV YPVKGYSITV PIVDEPASPR STVMDESYKV 310 320 330 340 350 360 AITRLGDRIR VGGTAEIGDY QPRLRPNRRV TLDRSLTDLF PGAGDLSQAT FWSGLRPMTP 370 380 390 400 410 420 DGPPIIGPTR LANLHLNTGH GTLGWTMACG AARVAVDQLR SVEPEIDARA LSLSRYQSGA ASLGA

References

[1]

"Complete sequence of Rhodopseudomonas palustris HaA2." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Pelletier D.A. , Kyrpides N., Anderson I., Oda Y., Harwood C.S., Richardson P. Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: HaA2.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000250 Genomic DNA. Translation: ABD06213.1.
RefSeq	YP_485124.1. NC_007778.1.
3D structure databases
ProteinModelPortal	Q2IZZ7.
ModBase	Search...
Protein-protein interaction databases
STRING	Q2IZZ7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3908416.
GenomeReviews	Gene locus RPB_1503 in contig CP000250_GR.
KEGG	rpb:RPB_1503.
PATRIC	23297585. VBIRhoPal125544_1587.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0665.
HOGENOM	HBG729204.
OMA	VDRQPAV.
ProtClustDB	PRK00711.
Enzyme and pathway databases
BioCyc	RPAL316058:RPB_1503-MONOMER.
Family and domain databases
HAMAP	MF_01202. DadA. [Tree]
InterPro	IPR023080. D-aa_DH_ssu_DadA. IPR006076. FAD-dep_OxRdtase. [Graphical view]
KO	K00285.
Pfam	PF01266. DAO. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DADA_RHOP2

Accession

Primary (citable) accession number: Q2IZZ7

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	March 7, 2006
Last modified:	January 25, 2012
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program